L773:0903 4641 OR L773:1600 0463
Search: L773:0903 4641 OR L773:1600 0463 > (2005-2009) > The contact/kinin a...
- 6 of 132
- Previous record
- Next record
- To hitlist
The contact/kinin and complement systems in vasculitis.
-
- Karpman, Diana (author)
- Lund University,Lunds universitet,Pediatrik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Pediatrisk nefrologi,Forskargrupper vid Lunds universitet,Paediatrics (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Pediatric Nephrology,Lund University Research Groups
-
- Kahn, Robin (author)
- Lund University,Lunds universitet,Pediatrik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Paediatrics (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine
- (creator_code:org_t)
- Wiley, 2009
- 2009
- English.
- In: APMIS Acta Pathologica, Microbiologica et Immunologica Scandinavica. Supplementum. - : Wiley. - 0903-465X. ; 117, s. 48-54
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- Vasculitides are a group of conditions with marked inflammation in and around vessel walls and vascular leakage. These conditions may involve the presence of auto-antibodies such as ANCA or may be mediated by other autoimmune or pathogenic mechanisms. Regardless of the primary trigger, vasculitides entail activation of the complement system as well as the contact/kinin system. In vivo and in vitro data support the involvement of these systems showing activation of the alternative, classical and lectin complement pathways as well as release of bradykinin at sites of vascular inflammation. This short review will summarize some of the data regarding the participation of these systems and the interplay between the complement and kinin systems as well as their interaction with the endothelium and neutrophils. Although these systems do not play a primary role in induction of vasculitis, the peptides released contribute to inflammation and vascular leakage and may thus be identified as potential therapeutic targets.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
Publication and Content Type
- art (subject category)
- ref (subject category)
Find in a library
- APMIS Acta Pathologica, Microbiologica et Immunologica Scandinavica. Supplementu... (Search for host publication in LIBRIS)
To the university's database
- 6 of 132
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Karpman, Diana
- Kahn, Robin
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Clinical Medicin ...
- and Pediatrics
- Articles in the publication
- APMIS Acta Patho ...
- APMIS
- By the university
- Lund University
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
