L773:1438 4221
Sökning: L773:1438 4221 > Signal transduction...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 02560naa a2200397 4500 | |
| 001 | oai:DiVA.org:umu-165897 | |
| 003 | SwePub | |
| 008 | 191216s2001 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1658972 URI |
| 024 | 7 | a https://doi.org/10.1078/1438-4221-001342 DOI |
| 040 | a (SwePub)umu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Popp, A4 aut |
| 245 | 1 0 | a Signal transduction pathways induced by virulence factors of Neisseria gonorrhoeae |
| 264 | 1 | b Elsevier BV,c 2001 |
| 338 | a print2 rdacarrier | |
| 520 | a The obligate human pathogen Neisseria gonorrhoeae infects a variety of human tissues. In recent years, several host cell receptors for the major bacterial adhesins have been identified. While the knowledge of the molecular mechanism of colonisation has helped to understand special aspects of the infection, like the explicit tropism of gonococci for human tissues, the long-term consequences of engaging these receptors are still unknown. A variety of signalling pathways initiated by the activated receptors and by bacterial proteins transferred to the infected cell have been defined which include lipid second messenger, protein kinases, proteases and GTPases. These pathways control important steps of the infection, such as tight adhesion and invasion, the induction of cytokine release, and apoptosis. The detailed knowledge of bacteria-induced signalling pathways could allow the design of new therapeutic approaches which might be advantageous over the classical antibiotics therapy. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Cell- och molekylärbiologi0 (SwePub)301082 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Cell and Molecular Biology0 (SwePub)301082 hsv//eng |
| 653 | a Bacterial Adhesion | |
| 653 | a Bacterial Proteins/*metabolism | |
| 653 | a Cell Line | |
| 653 | a Epithelial Cells/microbiology | |
| 653 | a Gonorrhea/*microbiology | |
| 653 | a Humans | |
| 653 | a Neisseria gonorrhoeae/*pathogenicity | |
| 653 | a *Signal Transduction | |
| 653 | a Virulence | |
| 700 | 1 | a Billker, Oliver4 aut |
| 700 | 1 | a Rudel, T4 aut |
| 773 | 0 | t International Journal of Medical Microbiologyd : Elsevier BVg 291:4, s. 307-314q 291:4<307-314x 1438-4221x 1618-0607 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-165897 |
| 856 | 4 8 | u https://doi.org/10.1078/1438-4221-00134 |
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