L773:1651 226X
Sökning: L773:1651 226X > (1990-1994) > Estrogen and proges...
LIBRIS Formathandbok (Information om MARC21)
| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03744naa a2200433 4500 | |
| 001 | oai:lup.lub.lu.se:ef5544a2-292c-4b25-b1e1-bd7c4c55130c | |
| 003 | SwePub | |
| 008 | 181219s1990 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://lup.lub.lu.se/record/ef5544a2-292c-4b25-b1e1-bd7c4c55130c2 URI |
| 024 | 7 | a https://doi.org/10.3109/028418690091265322 DOI |
| 040 | a (SwePub)lu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a art2 swepub-publicationtype |
| 072 | 7 | a ref2 swepub-contenttype |
| 100 | 1 | a Fernö, M.u Skåne University Hospital4 aut0 (Swepub:lu)onk-mfe |
| 245 | 1 0 | a Estrogen and progesterone receptor analyses in more than 4000 human breast cancer samples : A study with special reference to age at diagnosis and stability of analyses |
| 264 | c 2009-07-08 | |
| 264 | 1 | b Informa UK Limited,c 1990 |
| 520 | a Estrogen (ER) and progesterone receptors (PgR) were measured in the same laboratory in more than 4000 breast cancer biopsy samples obtained from 15 different hospitals during ten years. ER was measured with isoelectric focusing and PgR with the dextran-coated charcoal method and Scatchard analysis. The distribution pattern for both ER and PgR was during this time period and for the different hospitals rather similar indicating a good stability of the analytical methods. ER concentration was positively correlated with patient age, with a higher percentage of positive samples and higher concentrations in patients ≥50 years of age compared with patients <50 years. PgR concentration increased with age for patients under 50 years, but a considerable reduction of PgR concentration and of the proportion of positive samples was seen in patients between 50 and 59 years of age. Above this age the PgR concentration again increased with increasing age. The PgR/ER ratio and the proportion of ER- PgR+ samples were higher in patients under 50 years compared to older patients. ER and PgR values decreased during tamoxifen treatment, during pregnancy and after preoperative radiotherapy. Wet weight, DNA and protein were compared as reference parameters for the expression of ER and PgR concentrations. Strong correlations were obtained suggesting that similar information can be obtained with either of these reference parameters. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
| 653 | a Age | |
| 653 | a Breast cancer | |
| 653 | a Estrogen receptor | |
| 653 | a Progesterone receptor | |
| 653 | a Stability of analyses | |
| 700 | 1 | a Borg, Åu Skåne University Hospital4 aut0 (Swepub:lu)onk-abo |
| 700 | 1 | a Johansson, U.u Skåne University Hospital4 aut0 (Swepub:lu)onk-ujo |
| 700 | 1 | a Norgren, A.u Skåne University Hospital4 aut |
| 700 | 1 | a Olsson, H.u Lund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital4 aut0 (Swepub:lu)onk-hol |
| 700 | 1 | a Rydén, S.u Skåne University Hospital4 aut |
| 700 | 1 | a Sellberg, G.u Skåne University Hospital4 aut0 (Swepub:lu)onk-gse |
| 710 | 2 | a Skåne University Hospitalb Tumörmikromiljö4 org |
| 710 | 2 | a Southern Swedish Breast Cancer Study Group |
| 773 | 0 | t Acta Oncologicad : Informa UK Limitedg 29:2, s. 129-135q 29:2<129-135x 0284-186Xx 1651-226X |
| 856 | 4 | u http://dx.doi.org/10.3109/02841869009126532y FULLTEXT |
| 856 | 4 8 | u https://lup.lub.lu.se/record/ef5544a2-292c-4b25-b1e1-bd7c4c55130c |
| 856 | 4 8 | u https://doi.org/10.3109/02841869009126532 |
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- Fernö, M.
- Borg, Å
- Johansson, U.
- Norgren, A.
- Olsson, H.
- Rydén, S.
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- Sellberg, G.
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- Lunds universitet
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