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Longer colonic tran...
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Bohlin, JohanSkåne University Hospital,Lund University
(författare)
Longer colonic transit time is associated with laxative and drug use, Lifestyle factors and symptoms of constipation
- Artikel/kapitelEngelska2018
Förlag, utgivningsår, omfång ...
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2018-10-22
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SAGE Publications,2018
Nummerbeteckningar
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LIBRIS-ID:oai:lup.lub.lu.se:dcf4779f-c011-423c-93de-4be3650a6b6e
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https://lup.lub.lu.se/record/dcf4779f-c011-423c-93de-4be3650a6b6eURI
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https://doi.org/10.1177/2058460118807232DOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:art swepub-publicationtype
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Ämneskategori:ref swepub-contenttype
Anmärkningar
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Background Gastrointestinal symptoms and changes in colonic transit time (CTT) are common in the population. Purpose To evaluate consecutive patients who had been examined for CTT, along with completion of a diary about laxative and drug use, lifestyle factors, and gastrointestinal symptoms, to identify possible associations with longer or prolonged CTT. Material and Methods A total of 610 consecutive patients had undergone the radiopaque marker method with an abdominal X-ray for clinical purposes. The patients had completed a diary regarding medical treatment, lifestyle factors, stool habits, and their perceived constipation and abdominal pain during the examination period. The associations between CTT and laxative use, lifestyle factors, stool habits, and symptoms were calculated by logistic regression. Results Women had longer CTT (2.5 [1.6–3.9] vs. 1.7 [1.1–3.0] days, P < 0.001), lower weekly stool frequency (6 [3–10] vs. 8 [5–12], P = 0.001), and perceived more constipation (P = 0.025) and abdominal pain (P = 0.001) than men. High coffee consumption (P = 0.045), bulk-forming (P = 0.007) and osmotic (P = 0.001) laxatives, and lower stool frequency, shaped stool, and perceived constipation (P for trend < 0.001) were associated with longer CTT. In total, 382 patients (63%) were treated with drugs affecting motility. In the 228 patients without drug treatment, longer CTT was associated with female sex and smoking, and lower frequency of symptoms and prolonged CTT were observed compared to patients using drugs. Tea, alcohol, and abdominal pain did not associate with CTT. Conclusions Female sex, coffee, smoking, drug use, infrequent stools, shaped stool, and perception of constipation are associated with longer or prolonged CTT.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Dahlin, ErikSkåne University Hospital,Lund University
(författare)
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Dreja, JuliaLund University,Skåne University Hospital
(författare)
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Roth, BodilLund University,Lunds universitet,Gastroenterologi,Forskargrupper vid Lunds universitet,Klinisk koagulationsmedicin, Malmö,Gastroenterology,Lund University Research Groups,Clinical Coagulation, Malmö,Skåne University Hospital(Swepub:lu)medf-bro
(författare)
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Ekberg, OlleLund University,Lunds universitet,Diagnostisk radiologi, Malmö,Forskargrupper vid Lunds universitet,Radiology Diagnostics, Malmö,Lund University Research Groups,Skåne University Hospital(Swepub:lu)ront-oek
(författare)
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Ohlsson, BodilLund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups,Skåne University Hospital(Swepub:lu)kir-boh
(författare)
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Skåne University HospitalLund University
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Acta Radiologica Open: SAGE Publications7:102058-4601
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