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Acetabular dysplasi...
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Riedstra, N. S.Erasmus University Medical Center
(författare)
Acetabular dysplasia and the risk of developing hip osteoarthritis at 2,5,8, and 10 years follow-up in a prospective nationwide cohort study (CHECK).
- Artikel/kapitelEngelska2023
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Nummerbeteckningar
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LIBRIS-ID:oai:lup.lub.lu.se:c8c87563-603a-4851-8493-d718c70ae7fc
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https://lup.lub.lu.se/record/c8c87563-603a-4851-8493-d718c70ae7fcURI
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https://doi.org/10.1016/j.semarthrit.2023.152194DOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:art swepub-publicationtype
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Ämneskategori:ref swepub-contenttype
Anmärkningar
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Objective: To assess the relationship between acetabular dysplasia (AD) and the risk of incident and end-stage radiographic hip osteoarthritis (RHOA) over 2,5,8 and 10 years. Design: Individuals (n = 1002) aged between 45 and 65 from the prospective Cohort Hip and Cohort Knee (CHECK) were studied. Anteroposterior pelvic radiographs were obtained at baseline and 2,5,8, and 10-years follow-up. False profile radiographs were obtained at baseline. AD was defined as a lateral center edge angle, an anterior center edge angle, or both <25° at baseline. The risk of developing RHOA was determined at each follow-up moment. Incident RHOA was defined by Kellgren & Lawrence (KL) grade ≥2 or total hip replacement (THR), end-stage RHOA by a KL grade ≥3 or THR. Associations were expressed in odds ratios (OR) using logistic regression with generalized estimating equations. Results: AD was associated with the development of incident RHOA at 2 years follow-up (OR 2.46, 95% CI 1.00–6.04), 5 years follow-up (OR 2.28, 95% CI 1.20–4.31), and 8 years follow-up (OR 1.86, 95%CI 1.22–2.83). AD was only associated with end-stage RHOA at 5 years follow-up (OR 3.75, 95% CI 1.02–13.77). No statistically significant associations were observed between AD and RHOA at 10-years follow-up. Conclusion: Baseline AD in individuals between 45 and 65 years is associated with an increased risk of developing RHOA within 2- and 5 years. However, this association seems to weaken after 8 years and disappears after 10 years.
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Biuppslag (personer, institutioner, konferenser, titlar ...)
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Vinge, R.Lund University,Lunds universitet,Ortopedi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Lund OsteoArthritis Division - Höftsjukdomar från vaggan till protesen,Forskargrupper vid Lunds universitet,Orthopaedics (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund OsteoArthritis Division - Hip diseases from the cradle to the prosthesis,Lund University Research Groups(Swepub:lu)re0861le
(författare)
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Herfkens, J.Erasmus University Medical Center
(författare)
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Eygendaal, D.Erasmus University Medical Center
(författare)
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Bierma-Zeinstra, S. M.A.Erasmus University Medical Center
(författare)
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Runhaar, J.Erasmus University Medical Center
(författare)
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van Buuren, M. M.A.Erasmus University Medical Center
(författare)
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Agricola, R.Erasmus University Medical Center
(författare)
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Erasmus University Medical CenterOrtopedi, Lund
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Seminars in Arthritis and Rheumatism: Elsevier BV600049-0172
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