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Dropout from exercise trials among cancer survivors—An individual patient data meta-analysis from the POLARIS study

Western, Benedikte (author)
University of Agder, Kristiansand, Norway,Univ Agder, Dept Sport Sci & Phys Educ, Kristiansand, Norway.
Ivarsson, Andreas, 1984- (author)
Högskolan i Halmstad,Akademin för hälsa och välfärd,Halmstad Univ, Ctr Res Welf Hlth & Sport, Halmstad, Sweden.
Vistad, Ingvild (author)
University of Bergen, Bergen, Norway; Sørlandet Hospital, Kristiansand, Norway; Faculty of Medicine, Oslo, Norway,Univ Bergen, Dept Clin Sci, Bergen, Norway.;Sorlandet Hosp, Dept Obstet & Gynecol, Kristiansand, Norway.;Univ Oslo, Fac Med, Oslo, Norway.
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Demmelmaier, Ingrid, 1960- (author)
Uppsala universitet,Folkhälsa, arbetsliv och rehabilitering,Univ Agder, Dept Sport Sci & Phys Educ, Kristiansand, Norway
Aaronson, Neil K. (author)
Netherlands Cancer Institute, Amsterdam, Netherlands,Netherlands Canc Inst, Div Psychosocial Res & Epidemiol, Amsterdam, Netherlands.
Radcliffe, Gillian (author)
Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom,Guys & St Thomas NHS Fdn Trust, Lane Fox Resp Serv, London, England.
van Beurden, Marc (author)
Netherlands Cancer Institute, Amsterdam, Netherlands; Antoni van Leeuwenhoek Hospital, Amsterdam, Netherlands,Antoni van Leeuwenhoek Hosp, Netherlands Canc Inst, Amsterdam, Netherlands.
Bohus, Martin (author)
Central Institute of Mental Health, Mannheim, Germany; University Of Heidelberg, Heidelberg, Germany; University of Antwerp, Antwerpen, Belgium,Cent Inst Mental Hlth, Inst Psychiat & Psychosomat Psychotherapy, Mannheim, Germany.;Heidelberg Univ, Heidelberg, Germany.;Univ Antwerp, Fac Hlth Sci, Antwerp, Belgium.
Courneya, Kerry S. (author)
University of Alberta, Edmonton, Canada,Univ Alberta, Fac Kinesiol Sport & Recreat, Edmonton, AB, Canada.
Daley, Amanda J. (author)
Loughborough University, Loughborough, United Kingdom,Loughborough Univ, Ctr Lifestyle Med & Behav CLiMB, Sch Sport Exercise & Hlth Sci, Loughborough, England.
Galvão, Daniel A. (author)
Edith Cowan University, Perth, Australia,Edith Cowan Univ, Exercise Med Res Inst, Joondalup, WA, Australia.
Garrod, Rachel (author)
King's College London, London, United Kingdom,Kings Coll London, Dept Resp Med, London, England.
Goedendorp, Martine M. (author)
University of Groningen, Groningen, Netherlands; University Medical Center Groningen, Groningen, Netherlands,Univ Groningen, Dept Psychol, Groningen, Netherlands.;Univ Groningen, Univ Med Ctr Groningen, Dept Hlth Psychol, Groningen, Netherlands.
Griffith, Kathleen A. (author)
George Washington University, Washington, D.C., United States,George Washington Univ, Washington, DC USA.
van Harten, Wim H. (author)
Netherlands Cancer Institute, Amsterdam, Netherlands; University of Twente, Enschede, Netherlands,Netherlands Canc Inst, Div Psychosocial Res & Epidemiol, Amsterdam, Netherlands.;Univ Twente, Enschede, Netherlands.
Hayes, Sandi C. (author)
Queensland University of Technology, Brisbane, Australia,Queensland Univ Technol, Sch Publ Hlth, Inst Hlth & Biomed Innovat, Kelvin Grove, Qld, Australia.
Herrero-Roman, Fernando (author)
Fundación Giafys Cancer, Miranda de Ebro, Spain
Hiensch, Anouk E. (author)
University Medical Center Utrecht, Utrecht, Netherlands,Univ Utrecht, Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands.
Irwin, Melinda L. (author)
Yale University, New Haven, United States,Yale Sch Publ Hlth, New Haven, CT USA.
James, Erica (author)
The University of Newcastle, Newcastle, New South Wales, Australia,Univ Newcastle, Sch Med & Publ Hlth, Callaghan, NSW, Australia.
Kenkhuis, Marlou Floor (author)
Radboud University Medical Center, Nijmegen, Netherlands,Radboud Univ Nijmegen, Med Ctr, Dept Med Biosci, Nijmegen, Netherlands.
Kersten, Marie José (author)
Amsterdam University Medical Center, Amsterdam, Netherlands,Univ Amsterdam, Med Ctr, Canc Ctr Amsterdam, Dept Hematol, Amsterdam, Netherlands.;LYMMCARE, Amsterdam, Netherlands.
Knoop, Hans (author)
University of Amsterdam, Amsterdam, Netherlands,Univ Amsterdam, Dept Med Psychol, Amsterdam UMC, Amsterdam, Netherlands.
Lucia, Alejandro (author)
European University of Madrid, Madrid, Spain,European Univ, Madrid, Spain.
May, Anne M. (author)
University Medical Center Utrecht, Utrecht, Netherlands,Univ Utrecht, Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands.
McConnachie, Alex (author)
University of Glasgow, Glasgow, United Kingdom,Univ Glasgow, Sch Hlth & Wellbeing, Glasgow, Scotland.
van Mechelen, Willem (author)
Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; University Of Queensland, Brisbane, Australia; University of Cape Town, Cape Town, South Africa; University College Dublin, Dublin, Ireland,Univ Amsterdam, Amsterdam Univ Med Ctr, Dept Publ & Occupat Hlth, Amsterdam, Netherlands.;Univ Queensland, Fac Hlth & Behav Sci, Sch Human Movement & Nutr Sci, Brisbane, Australia.;Univ Cape Town, Fac Hlth Sci, Dept Human Biol, Cape Town, South Africa.;Univ Coll Dublin, UCD Sch Publ Hlth Physiotherapy & Sports Sci, Dublin, Ireland.
Mutrie, Nanette (author)
University of Edinburgh, Edinburgh, United Kingdom,Univ Edinburgh, Phys Act Hlth Res Ctr, Edinburgh, Scotland.
Newton, Robert U. (author)
Edith Cowan University, Perth, Australia,Edith Cowan Univ, Exercise Med Res Inst, Joondalup, WA, Australia.
Nollet, Frans (author)
University of Amsterdam, Amsterdam, Netherlands; Amsterdam Movement Sciences, Amsterdam, Netherlands,Amsterdam UMC Locat Univ Amsterdam, Dept Rehabil Med, Amsterdam, Netherlands.;Amsterdam Movement Sci Rehabil & Dev, Amsterdam, Netherlands.
Oldenburg, Hester S. (author)
Netherlands Cancer Institute, Amsterdam, Netherlands; Antoni van Leeuwenhoek Hospital, Amsterdam, Netherlands,Antoni van Leeuwenhoek Hosp, Netherlands Canc Inst, Amsterdam, Netherlands.
Plotnikoff, Ron (author)
The University of Newcastle, Newcastle, New South Wales, Australia,Univ Newcastle, Prior Res Ctr Phys Act & Nutr, Callaghan, NSW, Australia.
Schmidt, Martina E. (author)
German Cancer Research Center, Heidelberg, Germany,German Canc Res Ctr, Div Phys Act Prevent & Canc, Heidelberg, Germany.;Natl Ctr Tumor Dis NCT, Heidelberg, Germany.
Schmitz, Katie H. (author)
University of Pittsburgh, Pittsburgh, United States,Univ Pittsburgh, Pittsburgh, PA USA.
Schulz, Karl Heinz (author)
University Medical Center Hamburg-Eppendorf, University of Hamburg, Hamburg, Germany,Univ Med Ctr Hamburg Eppendorf, Competence Ctr Sports and Exercise Med Athleticum, Hamburg, Germany.;Univ Med Ctr Hamburg Eppendorf, Inst Med Psychol, Hamburg, Germany.
Short, Camille E. (author)
University of Melbourne, Melbourne, Australia,Univ Melbourne, Melbourne Ctr Behav Change, Melbourne Sch Psychol Sci, Melbourne, Australia.;Univ Melbourne, Melbourne Sch Hlth Sci, Canc & Exercise Recovery Res Grp CanRex, Melbourne, Vic, Australia.
Sonke, Gabe S. (author)
Antoni van Leeuwenhoek Hospital, Amsterdam, Netherlands,Antoni van Leeuwenhoek Hosp, Netherlands Canc Inst, Amsterdam, Netherlands.
Steindorf, Karen (author)
German Cancer Research Center, Heidelberg, Germany,German Canc Res Ctr, Div Phys Act Prevent & Canc, Heidelberg, Germany.;Natl Ctr Tumor Dis NCT, Heidelberg, Germany.
Stuiver, Martijn M. (author)
Netherlands Cancer Institute, Amsterdam, Netherlands,Netherlands Canc Inst, Div Psychosocial Res & Epidemiol, Amsterdam, Netherlands.
Taaffe, Dennis R. (author)
Edith Cowan University, Perth, Australia,Edith Cowan Univ, Exercise Med Res Inst, Joondalup, WA, Australia.
Thorsen, Lene (author)
Oslo University Hospital, Oslo, Norway; Oslo University Hospital, Oslo, Norway,Oslo Univ Hosp, Dept Oncol, Div Canc Med, Natl Advisory Unit Late Effects Canc Treatment, Oslo, Norway.;Oslo Univ Hosp, Dept Clin Serv, Div Canc Med, Oslo, Norway.
Velthuis, Miranda J. (author)
Netherlands Comprehensive Cancer Organisation (IKNL), Utrecht, Netherlands,Netherlands Comprehens Canc Org IKNL, Utrecht, Netherlands.
Wenzel, Jennifer (author)
Johns Hopkins University School of Medicine, Baltimore, United States,Sidney Kimmel Comprehens Canc Ctr, Johns Hopkins Sch Nursing, Johns Hopkins Sch Med, Baltimore, MD USA.
Winters-Stone, Kerri M. (author)
Oregon Health and Science University, Portland, United States,Oregon Hlth & Sci Univ, Knight Canc Inst, Portland, OR USA.
Wiskemann, Joachim (author)
German Cancer Research Center, Heidelberg, Germany,Natl Ctr Tumor Dis NCT Heidelberg, Dept Med Oncol, Heidelberg, Germany.;Heidelberg Univ Clin, Heidelberg, Germany.
Berntsen, Sveinung (author)
University of Agder, Kristiansand, Norway,Univ Agder, Dept Sport Sci & Phys Educ, Kristiansand, Norway.
Buffart, Laurien M. (author)
Radboud University Medical Center, Nijmegen, Netherlands,Radboudumc, Dept Physiol, Nijmegen, Netherlands.
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University of Agder, Kristiansand, Norway Univ Agder, Dept Sport Sci & Phys Educ, Kristiansand, Norway (creator_code:org_t)
Chichester, West Sussex : Wiley-Blackwell Publishing Inc. 2024
2024
English.
In: Scandinavian Journal of Medicine and Science in Sports. - Chichester, West Sussex : Wiley-Blackwell Publishing Inc.. - 0905-7188 .- 1600-0838. ; 34:2, s. 1-10
Related links:
https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
https://urn.kb.se/re...
https://doi.org/10.1...
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  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Introduction: The number of randomized controlled trials (RCTs) investigating the effects of exercise among cancer survivors has increased in recent years; however, participants dropping out of the trials are rarely described. The objective of the present study was to assess which combinations of participant and exercise program characteristics were associated with dropout from the exercise arms of RCTs among cancer survivors. Methods: This study used data collected in the Predicting OptimaL cAncer RehabIlitation and Supportive care (POLARIS) study, an international database of RCTs investigating the effects of exercise among cancer survivors. Thirty-four exercise trials, with a total of 2467 patients without metastatic disease randomized to an exercise arm were included. Harmonized studies included a pre and a posttest, and participants were classified as dropouts when missing all assessments at the post-intervention test. Subgroups were identified with a conditional inference tree. Results: Overall, 9.6% of the participants dropped out. Five subgroups were identified in the conditional inference tree based on four significant associations with dropout. Most dropout was observed for participants with BMI >28.4 kg/m2, performing supervised resistance or unsupervised mixed exercise (19.8% dropout) or had low-medium education and performed aerobic or supervised mixed exercise (13.5%). The lowest dropout was found for participants with BMI >28.4 kg/m2 and high education performing aerobic or supervised mixed exercise (5.1%), and participants with BMI ≤28.4 kg/m2 exercising during (5.2%) or post (9.5%) treatment. Conclusions: There are several systematic differences between cancer survivors completing and dropping out from exercise trials, possibly affecting the external validity of exercise effects. © 2024 The Authors. Scandinavian Journal of Medicine & Science In Sports published by John Wiley & Sons Ltd.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Idrottsvetenskap (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Sport and Fitness Sciences (hsv//eng)

Keyword

cancer
decision tree
exercise oncology
individual patient data meta-analysis
M4HP
M4HP

Publication and Content Type

ref (subject category)
art (subject category)

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