Zinc transporter 7 is located in the cis-Golgi apparatus of mouse choroid epithelial cells.

Chi, Zhi-Hong (author)

Wang, Xin (author)

Wang, Zhan-You (author)

Gao, Hui-Ling (author)

Dahlström, Annica, 1941 (author): Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för medicinsk kemi och cellbiologi,Institute of Biomedicine, Department of Medical Biochemistry and Cell Biology

Huang, Liping (author)

(creator_code:org_t)

Ovid Technologies (Wolters Kluwer Health), 2006
2006
English.
In: Neuroreport. - : Ovid Technologies (Wolters Kluwer Health). - 0959-4965. ; 17:17, s. 1807-11

Related links:: https://gup.ub.gu.se...; show more...; https://doi.org/10.1...; show less...

Abstract Subject headings

The cellular localization of zinc transporter 7 protein in the mouse choroid plexus was examined in this study. Zinc transporter 7 immunoreactive cells were detected in the third, lateral, and fourth ventricles of CD-1 mouse brain. Distinct zinc transporter 7 immunoreactivity was concentrated in the perinuclear regions of the positive cells. The results from zinc autometallography showed that zinc-positive grains were also predominantly located in the perinuclear areas. Ultrastructural localization showed that zinc transporter 7 immunostaining was predominantly present in the membrane and cisternae of the cis-Golgi networks and some vesicle compartments. The results support the notion that zinc transporter 7 may participate in the transport of the cytoplasmic zinc into the Golgi apparatus, and may be involved in local packaging of zinc-binding proteins in the mouse choroid plexus.

By the author/editor: Chi, Zhi-Hong; Wang, Xin; Wang, Zhan-You; Gao, Hui-Ling; Dahlström, Annic ...; Huang, Liping

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