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Sökning: WFRF:(Christensen Jane) > (2020-2024) > Comprehensive cardi...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003931naa a2200409 4500
001oai:gup.ub.gu.se/305707
003SwePub
008240528s2022 | |||||||||||000 ||eng|
0247 a https://gup.ub.gu.se/publication/3057072 URI
0247 a https://doi.org/10.1093/eurjcn/zvab0472 DOI
040 a (SwePub)gu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Rasmussen, Trine Bernholdt4 aut
2451 0a Comprehensive cardiac rehabilitation for patients following infective endocarditis: results of the randomized CopenHeartIE trial.
264 c 2021-06-05
264 1b Oxford University Press (OUP),c 2022
520 a Infective endocarditis is a complex and highly mortal disease requiring lengthy treatment. Physical and mental deconditioning is common. Nonetheless, rehabilitation is virtually unexplored in this population. The aim of this trial was therefore to investigate the effects of cardiac rehabilitation in patients following endocarditis.In a randomized trial, adults with left-sided or cardiac device endocarditis were randomized 1:1 to 12 weeks of physical exercise training and five psycho-educational consultations (cardiac rehabilitation) vs. usual care without rehabilitation (control). Primary outcome was mental health measured by SF-36 Mental Component Summary (MCS) at 6 months. Secondary outcome was physical capacity measured by peak oxygen uptake (VO2) at 4 months. Exploratory outcomes were investigated. Low inclusion rate resulted in trial termination before reaching the target sample size. A total of 117 participants (mean age: 60years, 81% male) were randomized to cardiac rehabilitation (n=58) or to control (n=59). Mental health and physical capacity at baseline were generally poor (MCS: 38.9-42.2 points, VO2 peak: 16.1-16.6mL/kg/min). Cardiac rehabilitation compared with control showed no effect on mental health (MCS: 44.6 points vs. 48.8 points, P=0.41) or physical capacity (VO2 peak: 19.9mL/kg/min vs. 18.0mL/kg/min, P=0.09). Effects favouring the intervention were identified in exploratory outcomes including general fatigue (P=0.005), and physical capacity as maximal power (W) (P=0.005). Adherence to the intervention was 28%.Results indicate no effect of cardiac rehabilitation in patients following endocarditis; however, lack of statistical power and poor adherence render findings inconclusive. Valuable insight into patients' capabilities and safety was gained, and further investigations into rehabilitation needs and modes of delivery in this high-need population should be a future priority.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskap0 (SwePub)3032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciences0 (SwePub)3032 hsv//eng
7001 a Zwisler, Ann-Dorthe4 aut
7001 a Risom, Signe Stelling4 aut
7001 a Sibilitz, Kirstine Lærum4 aut
7001 a Christensen, Jan4 aut
7001 a Bundgaard, Henning4 aut
7001 a Moons, Philip,d 1968u Gothenburg University,Göteborgs universitet,Institutionen för vårdvetenskap och hälsa,Institute of Health and Care Sciences4 aut0 (Swepub:gu)xmooph
7001 a Thygesen, Lau Caspar4 aut
7001 a Lindschou, Jane4 aut
7001 a Norekvål, Tone Merete4 aut
7001 a Berg, Selina Kikkenborg4 aut
7102 a Göteborgs universitetb Institutionen för vårdvetenskap och hälsa4 org
7730 t European journal of cardiovascular nursing : journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiologyd : Oxford University Press (OUP)g 21:3, s. 261-270q 21:3<261-270x 1873-1953
7730 t European Journal of Cardiovascular Nursingd : Oxford University Press (OUP)g 21:3, s. 261-270q 21:3<261-270x 1474-5151
8564 8u https://gup.ub.gu.se/publication/305707
8564 8u https://doi.org/10.1093/eurjcn/zvab047

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