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European Associatio...
European Association of Neuro-Oncology (EANO) guidelines for treatment of primary central nervous system lymphoma (PCNSL)
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- Hoang-Xuan, Khê (författare)
- APHP, Department of Neurology, Groupe Hospitalier Pitié-Salpêtrière; Sorbonne Université; IHU; ICM. Paris, France
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- Deckert, Martina (författare)
- Institute of Neuropathology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany
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- Ferreri, Andrés J M (författare)
- Lymphoma Unit, IRCCS San Raffaele Scientific Institute, Milano, Italy
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- Furtner, Julia (författare)
- Department of Biomedical and Imaging Image-guided Therapy Medical University of Vienna, Vienna, Austria
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- Gallego Perez-Larraya, Jaime (författare)
- Health Research Institute of Navarra (IdiSNA), Program in Solid Tumors, Foundation for the Applied Medical Research, Department of Neurology, Clinica Universidad de Navarra, Pamplona, Navarra, Spain
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- Henriksson, Roger (författare)
- Umeå universitet,Onkologi
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- Hottinger, Andreas F. (författare)
- Department of Oncology and Clinical Neurosciences, CHUV University Hospital Lausanne and University of Lausanne
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- Kasenda, Benjamin (författare)
- Department of Hematology/Oncology and Palliative Care, Klinikum Stuttgart, Stuttgart, Germany
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- Lefranc, Florence (författare)
- Department of Neurosurgery, Hôpital Erasme, Université Libre de Bruxelles, Belgium
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- Lossos, Alexander (författare)
- Head, Leslie and Michael Gaffin Center for Neuro-Oncology; Department of Oncology and Neurology; Hadassah-Hebrew University Medical Center; Jerusalem, Israel
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- McBain, Catherine (författare)
- Department of Clinical Oncology, The Christie NHS FT; Manchester; United Kingdom
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- Preusser, Matthias (författare)
- Division of Oncology, Department of Medicine I, Medical University of Vienna, Vienna, Austria
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- Roth, Patrick (författare)
- Department of Neurology & Brain Tumor Center, University Hospital and University of Zurich, Zurich, Switzerland
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- Rudà, Roberta (författare)
- Department of Neurology, Castelfranco Veneto/Treviso Hospital, Italy; Division of Neuro-Oncology, Department of Neuroscience, University of Turin, City of Health and Science University Hospital, Turin, Italy
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- Schlegel, Uwe (författare)
- Universitätsklinikum Knappschaftskrankenhaus Bochum GmbH, Germany
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- Soffietti, Riccardo (författare)
- Division of Neuro-Oncology, Department of Neuroscience, University of Turin, City of Health and Science University Hospital, Turin, Italy
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- Soussain, Carole (författare)
- Department of Hematology, Institut Curie, Site Saint-Cloud, PSL Research University, Paris, France
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- Taphoorn, Martin J B (författare)
- Department of Neurology, Leiden University Medical Center and Department of Neurology, Haaglanden Medical Center The Hague, Netherlands
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- Touitou, Valérie (författare)
- APHP, Department of Ophtalmology, Groupe Hospitalier Pitié-Salpêtrière; Sorbonne Université. Paris, France
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- Weller, Michael (författare)
- Department of Neurology & Brain Tumor Center, University Hospital and University of Zurich, Zurich, Switzerland
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- Bromberg, Jacoline E C (författare)
- Department of Neuro-Oncology, Erasmus MC University Medical Center Cancer Institute, Netherlands
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APHP, Department of Neurology, Groupe Hospitalier Pitié-Salpêtrière; Sorbonne Université; IHU; ICM Paris, France Institute of Neuropathology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany (creator_code:org_t)
- 2022-08-12
- 2023
- Engelska.
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Ingår i: Neuro-Oncology. - : Oxford University Press. - 1522-8517 .- 1523-5866. ; 25:1, s. 37-53
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- The management of primary central nervous system (PCNSL) is one of the most controversial topics in neuro-oncology because of the complexity of the disease and the limited number of controlled studies available. In 2021, given recent advances and the publication of practice-changing randomized trials, the European Association of Neuro-Oncology (EANO) created a multidisciplinary task force to update the previously published evidence-based guidelines for immunocompetent adult patients with PCNSL and added a section on immunosuppressed patients. The guideline provides consensus considerations and recommendations for the treatment of PCNSL, including intraocular manifestations and specific management of the elderly. The main changes from the previous guideline include strengthened evidence for the consolidation with ASCT in first-line treatment, prospectively assessed chemotherapy combinations for both young and elderly patients, clarification of the role of rituximab even though the data remain inconclusive, of the role of new agents, and the incorporation of immunosuppressed patients and primary ocular lymphoma. The guideline should aid the clinicians in everyday practice and decision making and serve as a basis for future research in the field.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- chemotherapy
- immunotherapy
- primary CNS lymphoma
- radiotherapy
- treatment
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Hoang-Xuan, Khê
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Deckert, Martina
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Ferreri, Andrés ...
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Furtner, Julia
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Gallego Perez-La ...
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Henriksson, Roge ...
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Hottinger, Andre ...
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Kasenda, Benjami ...
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Lefranc, Florenc ...
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Lossos, Alexande ...
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McBain, Catherin ...
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Preusser, Matthi ...
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Roth, Patrick
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Rudà, Roberta
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Schlegel, Uwe
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Soffietti, Ricca ...
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Soussain, Carole
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Taphoorn, Martin ...
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Touitou, Valérie
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Weller, Michael
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Bromberg, Jacoli ...
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