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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005488naa a2200481 4500
001oai:DiVA.org:uu-485646
003SwePub
008221006s2022 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:149999543
009oai:DiVA.org:liu-186814
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4856462 URI
0247 a https://doi.org/10.1245/s10434-022-11922-52 DOI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1499995432 URI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1868142 URI
040 a (SwePub)uud (SwePub)kid (SwePub)liu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Hayami, Masaruu Karolinska Univ Hosp, Dept Upper Abdominal Surg, Ctr Digest Dis, Stockholm, Sweden.;Japanese Fdn Canc Res, Canc Inst Hosp, Dept Surg Gastroenterol, Gastroenterol Ctr, Tokyo, Japan.4 aut
2451 0a Population-Based Cohort Study from a Prospective National Registry :b Better Long-Term Survival in Esophageal Cancer After Minimally Invasive Compared with Open Transthoracic Esophagectomy
264 c 2022-06-25
264 1b Springer Nature,c 2022
338 a print2 rdacarrier
520 a Background Recent research indicates long-term survival benefits of minimally invasive esophagectomy (MIE) compared with open esophagectomy (OE) for patients with esophageal and gastroesophageal junction (GEJ) cancers, but there is a need for more population-based studies. Methods We conducted a prospective population-based nationwide cohort study including all patients in Sweden diagnosed with esophageal or junctional cancer who underwent a transthoracic esophagectomy with intrathoracic anastomosis. Data were collected from the Swedish National Register for Esophageal and Gastric Cancer in 2006-2019. Patients were grouped into OE and MIE including hybrid MIE (HMIE) and totally MIE (TMIE). Overall survival and short-term postoperative outcomes were compared using Cox regression and logistic regression models, respectively. All models were adjusted for age, sex, American Society of Anesthesiologists (ASA) score, clinical T and N stage, neoadjuvant therapy, year of surgery, and hospital volume. Results Among 1404 patients, 998 (71.1%) underwent OE and 406 (28.9%) underwent MIE. Compared with OE, overall survival was better following MIE (hazard ratio [HR] 0.72, 95% confidence interval [CI] 0.55-0.94), TMIE (HR 0.67, 95% CI 0.47-0.94), and possibly also after HMIE (HR 0.76, 95% CI 0.56-1.02). MIE was associated with shorter operation time, less intraoperative bleeding, higher number of resected lymph nodes, and shorter hospital stay compared with OE. MIE was also associated with fewer overall complications (odds ratio [OR] 0.70, 95% CI 0.47-1.03) as well as non-surgical complications (OR 0.64, 95% CI 0.40-1.00). Conclusions MIE seems to offer better survival and similar or improved short-term postoperative outcomes in esophageal and GEJ cancers compared with OE in this unselected population-based cohort.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng
7001 a Ndegwa, Nelsonu Karolinska Inst, Div Surg, Dept Clin Sci Intervent & Technol CLINTEC, Stockholm, Sweden.;Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden.4 aut
7001 a Lindblad, Matsu Karolinska Institutet,Karolinska Univ Hosp, Sweden; Karolinska Inst, Sweden4 aut
7001 a Linder, Gustavu Uppsala universitet,Gastrointestinalkirurgi,Uppsala Univ, Sweden4 aut0 (Swepub:uu)gulin499
7001 a Hedberg, Jakob,d 1972-u Uppsala universitet,Gastrointestinalkirurgi,Uppsala Univ, Sweden4 aut0 (Swepub:uu)jakhe890
7001 a Edholm, Davidu Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Kirurgiska kliniken US4 aut0 (Swepub:liu)daved38
7001 a Johansson, Janu Karolinska Institutet,Skane Univ Hosp, Sweden4 aut
7001 a Lagergren, Jesperu Karolinska Univ Hosp, Karolinska Inst, Dept Mol Med & Surg, Upper Gastrointestinal Surg, Stockholm, Sweden.;Kings Coll London, Sch Canc & Pharmaceut Sci, London, England.4 aut
7001 a Lundell, Larsu Karolinska Inst, Div Surg, Dept Clin Sci Intervent & Technol CLINTEC, Stockholm, Sweden.;Odense Univ Hosp, Dept Surg, Odense, Denmark.4 aut
7001 a Nilsson, Magnusu Karolinska Institutet,Karolinska Univ Hosp, Sweden; Karolinska Inst, Sweden4 aut
7001 a Rouvelas, Ioannisu Karolinska Institutet,Karolinska Univ Hosp, Sweden; Karolinska Inst, Sweden4 aut
7102 a Karolinska Univ Hosp, Dept Upper Abdominal Surg, Ctr Digest Dis, Stockholm, Sweden.;Japanese Fdn Canc Res, Canc Inst Hosp, Dept Surg Gastroenterol, Gastroenterol Ctr, Tokyo, Japan.b Karolinska Inst, Div Surg, Dept Clin Sci Intervent & Technol CLINTEC, Stockholm, Sweden.;Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden.4 org
7730 t Annals of Surgical Oncologyd : Springer Natureg 29:9, s. 5609-5621q 29:9<5609-5621x 1068-9265x 1534-4681
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-485646
8564 8u https://doi.org/10.1245/s10434-022-11922-5
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:149999543
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-186814

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