Sökning: WFRF:(Jack T.) > (2015-2019) > Global, regional, a...
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001 | oai:DiVA.org:miun-27325 | |
003 | SwePub | |
008 | 160323s2015 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:du-21318 | |
009 | oai:DiVA.org:uu-264732 | |
009 | oai:gup.ub.gu.se/248985 | |
009 | oai:prod.swepub.kib.ki.se:132606693 | |
009 | oai:lup.lub.lu.se:090be269-3fc1-422b-bac9-de195a8de4a4 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-273252 URI |
024 | 7 | a https://doi.org/10.1016/S0140-6736(15)00128-22 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:du-213182 URI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2647322 URI |
024 | 7 | a https://gup.ub.gu.se/publication/2489852 URI |
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024 | 7 | a https://lup.lub.lu.se/record/090be269-3fc1-422b-bac9-de195a8de4a42 URI |
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041 | a engb eng | |
042 | 9 SwePub | |
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100 | 1 | a Forouzanfar, Mohammad Hu Karolinska Institutet,University of Washington, Seattle4 aut |
245 | 1 0 | a Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013 :b a systematic analysis for the Global Burden of Disease Study 2013. |
264 | 1 | c 2015 |
338 | a electronic2 rdacarrier | |
520 | a BACKGROUND: The Global Burden of Disease, Injuries, and Risk Factor study 2013 (GBD 2013) is the first of a series of annual updates of the GBD. Risk factor quantification, particularly of modifiable risk factors, can help to identify emerging threats to population health and opportunities for prevention. The GBD 2013 provides a timely opportunity to update the comparative risk assessment with new data for exposure, relative risks, and evidence on the appropriate counterfactual risk distribution.METHODS: Attributable deaths, years of life lost, years lived with disability, and disability-adjusted life-years (DALYs) have been estimated for 79 risks or clusters of risks using the GBD 2010 methods. Risk-outcome pairs meeting explicit evidence criteria were assessed for 188 countries for the period 1990-2013 by age and sex using three inputs: risk exposure, relative risks, and the theoretical minimum risk exposure level (TMREL). Risks are organised into a hierarchy with blocks of behavioural, environmental and occupational, and metabolic risks at the first level of the hierarchy. The next level in the hierarchy includes nine clusters of related risks and two individual risks, with more detail provided at levels 3 and 4 of the hierarchy. Compared with GBD 2010, six new risk factors have been added: handwashing practices, occupational exposure to trichloroethylene, childhood wasting, childhood stunting, unsafe sex, and low glomerular filtration rate. For most risks, data for exposure were synthesised with a Bayesian meta-regression method, DisMod-MR 2.0, or spatial-temporal Gaussian process regression. Relative risks were based on meta-regressions of published cohort and intervention studies. Attributable burden for clusters of risks and all risks combined took into account evidence on the mediation of some risks such as high body-mass index (BMI) through other risks such as high systolic blood pressure and high cholesterol.FINDINGS: All risks combined account for 57·2% (95% uncertainty interval [UI] 55·8-58·5) of deaths and 41·6% (40·1-43·0) of DALYs. Risks quantified account for 87·9% (86·5-89·3) of cardiovascular disease DALYs, ranging to a low of 0% for neonatal disorders and neglected tropical diseases and malaria. In terms of global DALYs in 2013, six risks or clusters of risks each caused more than 5% of DALYs: dietary risks accounting for 11·3 million deaths and 241·4 million DALYs, high systolic blood pressure for 10·4 million deaths and 208·1 million DALYs, child and maternal malnutrition for 1·7 million deaths and 176·9 million DALYs, tobacco smoke for 6·1 million deaths and 143·5 million DALYs, air pollution for 5·5 million deaths and 141·5 million DALYs, and high BMI for 4·4 million deaths and 134·0 million DALYs. Risk factor patterns vary across regions and countries and with time. In sub-Saharan Africa, the leading risk factors are child and maternal malnutrition, unsafe sex, and unsafe water, sanitation, and handwashing. In women, in nearly all countries in the Americas, north Africa, and the Middle East, and in many other high-income countries, high BMI is the leading risk factor, with high systolic blood pressure as the leading risk in most of Central and Eastern Europe and south and east Asia. For men, high systolic blood pressure or tobacco use are the leading risks in nearly all high-income countries, in north Africa and the Middle East, Europe, and Asia. For men and women, unsafe sex is the leading risk in a corridor from Kenya to South Africa.INTERPRETATION: Behavioural, environmental and occupational, and metabolic risks can explain half of global mortality and more than one-third of global DALYs providing many opportunities for prevention. Of the larger risks, the attributable burden of high BMI has increased in the past 23 years. In view of the prominence of behavioural risk factors, behavioural and social science research on interventions for these risks should be strengthened. Many prevention and primary care policy options are available now to act on key risks.FUNDING: Bill & Melinda Gates Foundation. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskap0 (SwePub)3032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciences0 (SwePub)3032 hsv//eng |
653 | a Hälsa och välfärd | |
653 | a Environmental Exposure | |
653 | a adverse effects | |
653 | a Female | |
653 | a Global Health | |
653 | a statistics & numerical data | |
653 | a trends | |
653 | a Health Behavior | |
653 | a Humans | |
653 | a Male | |
653 | a Metabolic Diseases | |
653 | a epidemiology | |
653 | a Nutritional Status | |
653 | a Occupational Diseases | |
653 | a Occupational Exposure | |
653 | a Risk Assessment | |
653 | a methods | |
653 | a Risk Factors | |
653 | a Sanitation | |
653 | a tobacco smoke | |
653 | a trichloroethylene | |
653 | a Africa south of the Sahara | |
653 | a Bayes theorem | |
653 | a body mass | |
653 | a cardiovascular disease | |
653 | a Central European | |
653 | a comparative study | |
653 | a disability | |
653 | a disability adjusted life years | |
653 | a East Asian | |
653 | a Eastern Europe | |
653 | a environmental exposure | |
653 | a female | |
653 | a glomerulus filtration rate | |
653 | a hand washing | |
653 | a human | |
653 | a hypercholesterolemia | |
653 | a Kenya | |
653 | a male | |
653 | a malnutrition | |
653 | a Middle East | |
653 | a newborn disease | |
653 | a North America | |
653 | a occupational exposure | |
653 | a occupational hazard | |
653 | a priority journal | |
653 | a quality of life assessment | |
653 | a Review | |
653 | a risk assessment | |
653 | a sanitation | |
653 | a South Africa | |
653 | a stunting | |
653 | a systolic blood pressure | |
653 | a unsafe sex | |
653 | a water supply | |
653 | a years of life lost | |
700 | 1 | a Alexander, Lilyu University of Washington, Seattle4 aut |
700 | 1 | a Anderson, H Ross4 aut |
700 | 1 | a Bachman, Victoria Fu University of Washington4 aut |
700 | 1 | a Biryukov, Stanu Institute for Health Metrics and Evaluation4 aut |
700 | 1 | a Brauer, Michaelu University of British Columbia4 aut |
700 | 1 | a Burnett, Richard4 aut |
700 | 1 | a Casey, Danielu University of Washington, Seattle4 aut |
700 | 1 | a Coates, Matthew M4 aut |
700 | 1 | a Cohen, Aaron4 aut |
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700 | 1 | a Abraham, Biju4 aut |
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700 | 1 | a Abubakar, Ibrahim4 aut |
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700 | 1 | a Agardh, Emilie Eu Karolinska Institutet4 aut |
700 | 1 | a Al Khabouri, Mazin J4 aut |
700 | 1 | a Al Lami, Faris H4 aut |
700 | 1 | a Alam, Sayed Saidul4 aut |
700 | 1 | a Alasfoor, Deena4 aut |
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700 | 1 | a Ali, Mohammed Ku Karolinska Institutet4 aut |
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700 | 1 | a Allebeck, Peteru Karolinska Institutet4 aut |
700 | 1 | a Allen, Peter J4 aut |
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700 | 1 | a Arsenijevic, Valentina S Arsicu Karolinska Institutet4 aut |
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700 | 1 | a Lan, Qing4 aut |
700 | 1 | a Lansingh, Van C4 aut |
700 | 1 | a Larson, Heidi J4 aut |
700 | 1 | a Larsson, Andersu Uppsala universitet,Biokemisk struktur och funktion4 aut0 (Swepub:uu)andlarss |
700 | 1 | a Laryea, Dennis O4 aut |
700 | 1 | a Lavados, Pablo M4 aut |
700 | 1 | a Lawrynowicz, Alicia E4 aut |
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700 | 1 | a Leigh, James4 aut |
700 | 1 | a Leung, Ricky4 aut |
700 | 1 | a Levi, Miriam4 aut |
700 | 1 | a Li, Yichong4 aut |
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700 | 1 | a Liang, Juan4 aut |
700 | 1 | a Liang, Xiaofeng4 aut |
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700 | 1 | a Lipshultz, Steven E4 aut |
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700 | 1 | a Magis-Rodriguez, Carlos4 aut |
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700 | 1 | a Majdan, Marek4 aut |
700 | 1 | a Malekzadeh, Reza4 aut |
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700 | 1 | a Marcenes, Wagner4 aut |
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700 | 1 | a Mayosi, Bongani M4 aut |
700 | 1 | a Mazorodze, Tasara T4 aut |
700 | 1 | a McKay, Abigail C4 aut |
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700 | 1 | a Meaney, Peter A4 aut |
700 | 1 | a Medina, Catalina4 aut |
700 | 1 | a Mehndiratta, Man Mohan4 aut |
700 | 1 | a Mejia-Rodriguez, Fabiola4 aut |
700 | 1 | a Mekonnen, Wubegzier4 aut |
700 | 1 | a Melaku, Yohannes A4 aut |
700 | 1 | a Meltzer, Michele4 aut |
700 | 1 | a Memish, Ziad A4 aut |
700 | 1 | a Mendoza, Walter4 aut |
700 | 1 | a Mensah, George A4 aut |
700 | 1 | a Meretoja, Atte4 aut |
700 | 1 | a Mhimbira, Francis Apolinary4 aut |
700 | 1 | a Micha, Renata4 aut |
700 | 1 | a Miller, Ted R4 aut |
700 | 1 | a Mills, Edward J4 aut |
700 | 1 | a Misganaw, Awoke4 aut |
700 | 1 | a Mishra, Santosh4 aut |
700 | 1 | a Mohamed Ibrahim, Norlinah4 aut |
700 | 1 | a Mohammad, Karzan A4 aut |
700 | 1 | a Mokdad, Ali H4 aut |
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700 | 1 | a Montañez Hernandez, Julio C4 aut |
700 | 1 | a Montico, Marcella4 aut |
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700 | 1 | a Moschandreas, Joanna4 aut |
700 | 1 | a Moturi, Wilkister N4 aut |
700 | 1 | a Mozaffarian, Dariush4 aut |
700 | 1 | a Mueller, Ulrich O4 aut |
700 | 1 | a Mukaigawara, Mitsuru4 aut |
700 | 1 | a Mullany, Erin C4 aut |
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700 | 1 | a Nahas, Ziad4 aut |
700 | 1 | a Naheed, Aliya4 aut |
700 | 1 | a Naidoo, Kovin S4 aut |
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700 | 1 | a Nangia, Vinay4 aut |
700 | 1 | a Narayan, K M Venkat4 aut |
700 | 1 | a Nash, Denis4 aut |
700 | 1 | a Neal, Bruce4 aut |
700 | 1 | a Nejjari, Chakib4 aut |
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700 | 1 | a Nogueira, José R4 aut |
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700 | 1 | a Norheim, Ole F4 aut |
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700 | 1 | a Olusanya, Bolajoko O4 aut |
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856 | 4 | u https://miun.diva-portal.org/smash/get/diva2:913941/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 | u http://dx.doi.org/10.1016/S0140-6736(15)00128-2y FULLTEXT |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-27325 |
856 | 4 8 | u https://doi.org/10.1016/S0140-6736(15)00128-2 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:du-21318 |
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856 | 4 8 | u https://gup.ub.gu.se/publication/248985 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:132606693 |
856 | 4 8 | u https://lup.lub.lu.se/record/090be269-3fc1-422b-bac9-de195a8de4a4 |
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