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WFRF:(Ljungman David)
 

Search: WFRF:(Ljungman David) > (2005-2009) > Proteasome inhibiti...

Proteasome inhibition activates epidermal growth factor receptor (EGFR) and EGFR-independent mitogenic kinase signaling pathways in pancreatic cancer cells.

Sloss, Callum M (author)
Wang, Fang (author)
Liu, Rong (author)
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Xia, Lijun (author)
Houston, Michael (author)
Ljungman, David (author)
Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery
Palladino, Michael A (author)
Cusack, James C (author)
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 (creator_code:org_t)
2008
2008
English.
In: Clinical cancer research : an official journal of the American Association for Cancer Research. - 1078-0432. ; 14:16, s. 5116-23
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • In the current study, we investigate the activation of antiapoptotic signaling pathways in response to proteasome inhibitor treatment in pancreatic cancer and evaluate the use of concomitant inhibition of these pathways to augment proteasome inhibitor treatment responses.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kirurgi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Surgery (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)

Keyword

Adenocarcinoma
drug therapy
metabolism
Animals
Antibodies
Monoclonal
administration & dosage
Antibodies
Monoclonal
Humanized
Antineoplastic Combined Chemotherapy Protocols
therapeutic use
Apoptosis
drug effects
physiology
Blotting
Western
Boronic Acids
administration & dosage
Cell Line
Tumor
Deoxycytidine
administration & dosage
analogs & derivatives
Female
Humans
Lactones
administration & dosage
Mice
Mice
Nude
Pancreatic Neoplasms
drug therapy
metabolism
Phosphatidylinositol 3-Kinases
drug effects
metabolism
Protease Inhibitors
therapeutic use
Proteasome Inhibitors
Pyrazines
administration & dosage
Pyrroles
administration & dosage
Quinazolines
administration & dosage
Receptor
Epidermal Growth Factor
drug effects
metabolism
Signal Transduction
drug effects
physiology
Xenograft Model Antitumor Assays

Publication and Content Type

ref (subject category)
art (subject category)

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