Sökning: WFRF:(Nielsen Ewa) > Influence of Geneti...
Fältnamn | Indikatorer | Metadata |
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000 | 08374naa a2200697 4500 | |
001 | oai:DiVA.org:mau-53857 | |
003 | SwePub | |
008 | 220712s2022 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-538572 URI |
024 | 7 | a https://doi.org/10.1136/bmjopen-2021-0557792 DOI |
040 | a (SwePub)mau | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Attauabi, Mohamedu Department of Gastroenterology and Hepatology, Herlev Hospital, Herlev, Denmark4 aut |
245 | 1 0 | a Influence of Genetics, Immunity and the Microbiome on the Prognosis of Inflammatory Bowel Disease (IBD Prognosis Study) :b the protocol for a Copenhagen IBD Inception Cohort Study |
264 | c 2022-06-27 | |
264 | 1 | b BMJ Publishing Group Ltd,c 2022 |
338 | a electronic2 rdacarrier | |
520 | a Introduction: Inflammatory bowel diseases (IBD), encompassing Crohn's disease and ulcerative colitis, are chronic, inflammatory diseases of the gastrointestinal tract. We have initiated a Danish population-based inception cohort study aiming to investigate the underlying mechanisms for the heterogeneous course of IBD, including need for, and response to, treatment.Methods and analysis: IBD Prognosis Study is a prospective, population-based inception cohort study of unselected, newly diagnosed adult, adolescent and paediatric patients with IBD within the uptake area of Hvidovre University Hospital and Herlev University Hospital, Denmark, which covers approximately 1 050 000 inhabitants (~20% of the Danish population). The diagnosis of IBD will be according to the Porto diagnostic criteria in paediatric and adolescent patients or the Copenhagen diagnostic criteria in adult patients. All patients will be followed prospectively with regular clinical examinations including ileocolonoscopies, MRI of the small intestine, validated patient-reported measures and objective examinations with intestinal ultrasound. In addition, intestinal biopsies from ileocolonoscopies, stool, rectal swabs, saliva samples, swabs of the oral cavity and blood samples will be collected systematically for the analysis of biomarkers, microbiome and genetic profiles. Environmental factors and quality of life will be assessed using questionnaires and, when available, automatic registration of purchase data. The occurrence and course of extraintestinal manifestations will be evaluated by rheumatologists, dermatologists and dentists, and assessed by MR cholangiopancreatography, MR of the spine and sacroiliac joints, ultrasonography of peripheral joints and entheses, clinical oral examination, as well as panoramic radiograph of the jaws. Fibroscans and dual-energy X-ray absorptiometry scans will be performed to monitor occurrence and course of chronic liver diseases, osteopenia and osteoporosis.Ethics and dissemination: This study has been approved by Ethics Committee of the Capital Region of Denmark (approval number: H-20065831). Study results will be disseminated through publication in international scientific journals and presentation at (inter)national conferences. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Odontologi0 (SwePub)302162 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Dentistry0 (SwePub)302162 hsv//eng |
700 | 1 | a Madsen, Gorm Roageru Copenhagen Center for Inflammatory Bowel Disease in Children, Adolescents and Adults, Hvidovre Hospital, Hvidovre, Denmark4 aut |
700 | 1 | a Bendtsen, Flemmingu Gastrounit, Medical Section, Hvidovre Hospital, Hvidovre, Denmark4 aut |
700 | 1 | a Wewer, Anne Vibekeu The Paediatric Department, Hvidovre Hospital, Hvidovre, Denmark4 aut |
700 | 1 | a Wilkens, Runeu Gastrounit, Medical Section, Hvidovre Hospital, Hvidovre, Denmark4 aut |
700 | 1 | a Ilvemark, Johanu Department of Gastroenterology and Hepatology, Herlev Hospital, Herlev, Denmark4 aut |
700 | 1 | a Vladimirova, Norau Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark4 aut |
700 | 1 | a Jensen, Annette Bøjeru Department of Radiology, Centre for Functional and Diagnostic Imaging and Research, Hvidovre Hospital, Hvidovre, Denmark4 aut |
700 | 1 | a Jensen, Frank Kriegeru Department of Radiology, Centre for Functional and Diagnostic Imaging and Research, Hvidovre Hospital, Hvidovre, Denmark4 aut |
700 | 1 | a Hansen, Sanja Bayu Department of Radiology, Centre for Functional and Diagnostic Imaging and Research, Hvidovre Hospital, Hvidovre, Denmark4 aut |
700 | 1 | a Siebner, Hartwig Romanu Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Hvidovre Hospital, Hvidovre, Denmark4 aut |
700 | 1 | a Nielsen, Yousef Jesper Wirenfeldtu Department of Radiology, Herlev Hospital, Herlev, Denmark4 aut |
700 | 1 | a Møller, Jakob Mu Department of Radiology, Herlev Hospital, Herlev, Denmark4 aut |
700 | 1 | a Thomsen, Henrik Su Department of Radiology, Herlev Hospital, Herlev, Denmark4 aut |
700 | 1 | a Thomsen, Simon Francisu Department of Dermatology, Bispebjerg Hospital, Kobenhavn, Denmark4 aut |
700 | 1 | a Ingels, Helene Andrea Sinclairu Department of Paediatrics and Adolescent Medicine, Copenhagen University Hospital, Kobenhavn, Denmark4 aut |
700 | 1 | a Theede, Klausu Gastrounit, Medical Section, Hvidovre Hospital, Hvidovre, Denmark4 aut |
700 | 1 | a Boysen, Trineu Gastrounit, Medical Section, Hvidovre Hospital, Hvidovre, Denmark4 aut |
700 | 1 | a Bjerrum, Jacob Tu Department of Gastroenterology and Hepatology, Herlev Hospital, Herlev, Denmark4 aut |
700 | 1 | a Jakobsen, Christianu Copenhagen Center for Inflammatory Bowel Disease in Children, Adolescents and Adults, Hvidovre Hospital, Hvidovre, Denmark4 aut |
700 | 1 | a Dorn-Rasmussen, Mariau Copenhagen Center for Inflammatory Bowel Disease in Children, Adolescents and Adults, Hvidovre Hospital, Hvidovre, Denmark4 aut |
700 | 1 | a Jansson, Sabineu Copenhagen Center for Inflammatory Bowel Disease in Children, Adolescents and Adults, Hvidovre Hospital, Hvidovre, Denmark4 aut |
700 | 1 | a Yao, Yiqiuu Department of Dermatology, Bispebjerg Hospital, Kobenhavn, Denmark4 aut |
700 | 1 | a Burian, Ewa Annau Department of Dermatology, Bispebjerg Hospital, Kobenhavn, Denmark4 aut |
700 | 1 | a Møller, Frederik Trieru Department of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Kobenhavn, Denmark4 aut |
700 | 1 | a Fana, Viktoriau Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Kobenhavn, Denmark4 aut |
700 | 1 | a Wiell, Charlotteu Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Kobenhavn, Denmark4 aut |
700 | 1 | a Terslev, Leneu Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet Glostrup, Glostrup, Denmark4 aut |
700 | 1 | a Østergaard, Mikkelu Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Kobenhavn, Denmark4 aut |
700 | 1 | a Bertl, Kristinau Malmö universitet,Odontologiska fakulteten (OD),Periodontology4 aut0 (Swepub:mau)ae0620 |
700 | 1 | a Stavropoulos, Andreasu Malmö universitet,Odontologiska fakulteten (OD),Periodontology4 aut0 (Swepub:mau)ac3062 |
700 | 1 | a Seidelin, Jakob Bu Department of Gastroenterology and Hepatology, Herlev Hospital, Herlev, Denmark4 aut |
700 | 1 | a Burisch, Johanu Copenhagen Center for Inflammatory Bowel Disease in Children, Adolescents and Adults, Hvidovre Hospital, Hvidovre, Denmark4 aut |
710 | 2 | a Department of Gastroenterology and Hepatology, Herlev Hospital, Herlev, Denmarkb Copenhagen Center for Inflammatory Bowel Disease in Children, Adolescents and Adults, Hvidovre Hospital, Hvidovre, Denmark4 org |
773 | 0 | t BMJ Opend : BMJ Publishing Group Ltdg 12:6, s. e055779-e055779q 12:6<e055779-e055779x 2044-6055 |
856 | 4 | u https://doi.org/10.1136/bmjopen-2021-055779y Fulltext |
856 | 4 | u https://mau.diva-portal.org/smash/get/diva2:1682894/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-53857 |
856 | 4 8 | u https://doi.org/10.1136/bmjopen-2021-055779 |
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