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Construct validity of ILAR and EULAR criteria in juvenile idiopathic arthritis : a population based incidence study from the Nordic countries. International League of Associations for Rheumatology. European League Against Rheumatism

Berntson, L. (författare)
Fasth, A. (författare)
Andersson-Gäre, Boel (författare)
Jönköping University,HHJ. Kvalitetsförbättringar, innovationer och ledarskap inom vård och socialt arbete
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Kristinsson, J. (författare)
Lahdenne, P. (författare)
Marhaug, G. (författare)
Nielsen, S. (författare)
Pelkonen, P. (författare)
Svensson, E. (författare)
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Jönköping University HHJ Kvalitetsförbättringar, innovationer och ledarskap inom vård och socialt arbete (creator_code:org_t)
2001
2001
Engelska.
Ingår i: Journal of Rheumatology. - 0315-162X .- 1499-2752. ; 28:12, s. 2737-43
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • OBJECTIVE: New classification criteria (ILAR) have been proposed for juvenile idiopathic arthritis (JIA). They are more descriptive than those formerly used [American College of Rheumatology (ACR), European League Against Rheumatism (EULAR)], but require validation against classifications already in use. We validated the ILAR criteria in relation to the EULAR criteria in a prospective, incidence, and population based setting, and analyzed their feasibility. METHODS: Construct validity of ILAR and EULAR classification criteria refers to how closely the 2 instruments are related and how each of them operates in classifying subgroups/categories. Twenty doctors in 5 Nordic countries collected data from the incidence cases within their catchment areas during an 18 month period beginning July 1, 1997. Clinical and serological data from the first year of disease were collected. RESULTS: A total of 322 patients were included. Classification according to the ILAR criteria was possible in 321 patients; 290 patients had a disease duration > or = 3 months and were classified according to the EULAR criteria. One child could only be classified according to the EULAR criteria. Thus, 31/322 (9.6%) children were classified according to the ILAR criteria only. Forty-eight of 321 (15%) patients did not fit into any category and 6% (20/321) fulfilled criteria for2 categories. In the ILAR classification 5 out of 7 categories/subgroups have 2 to 5 specified exclusion criteria that highly discriminate the definition of each patient. In our study the exclusion criteria were fulfilled to only a small extent. CONCLUSION: The EULAR and ILAR criteria differ concerning the operational definitions of the subvariables involved, which complicates their comparison. By using ILAR rather than EULAR criteria the number of cases with juvenile arthritis increased by 10%, considering the first half-year after onset. The validity of the ILAR criteria is low since they often exclude patients from subgroup classification and the possibility of having more than one diagnosis is not negligible. The specified exclusion criteria for some of the subgroups are difficult to fulfill in clinical work and variables involved could be questioned with regard to their consistency.

Nyckelord

Adolescent
Arthritis
Juvenile Rheumatoid/*classification/epidemiology
Child
Child
Preschool
Female
Finland/epidemiology
Humans
Iceland/epidemiology
Incidence
Infant
International Cooperation
Male
Prospective Studies
Rheumatology/*methods/standards
Scandinavia/epidemiology
Societies
Medical

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