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Diabetes and heart ...
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Chadalavada, SucharithaWilliam Harvey Research Institute, NIHR Barts Biomedical Research Centre, Queen Mary University of London, Charterhouse Square, London, United Kingdom; Barts Heart Centre, St Bartholomew’s Hospital, Barts Health NHS Trust, West Smithfield, London, United Kingdom
(författare)
Diabetes and heart failure associations in women and men : Results from the MORGAM consortium
- Artikel/kapitelEngelska2023
Förlag, utgivningsår, omfång ...
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2023
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electronicrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:umu-208959
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-208959URI
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https://doi.org/10.3389/fcvm.2023.1136764DOI
Kompletterande språkuppgifter
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Språk:engelska
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Sammanfattning på:engelska
Ingår i deldatabas
Klassifikation
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
Anmärkningar
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Background: Diabetes and its cardiovascular complications are a growing concern worldwide. Recently, some studies have demonstrated that relative risk of heart failure (HF) is higher in women with type 1 diabetes (T1DM) than in men. This study aims to validate these findings in cohorts representing five countries across Europe.Methods: This study includes 88,559 (51.8% women) participants, 3,281 (46.3% women) of whom had diabetes at baseline. Survival analysis was performed with the outcomes of interest being death and HF with a follow-up time of 12 years. Sub-group analysis according to sex and type of diabetes was also performed for the HF outcome.Results: 6,460 deaths were recorded, of which 567 were amongst those with diabetes. Additionally, HF was diagnosed in 2,772 individuals (446 with diabetes). A multivariable Cox proportional hazard analysis showed that there was an increased risk of death and HF (hazard ratio (HR) of 1.73 [1.58–1.89] and 2.12 [1.91–2.36], respectively) when comparing those with diabetes and those without. The HR for HF was 6.72 [2.75–16.41] for women with T1DM vs. 5.80 [2.72–12.37] for men with T1DM, but the interaction term for sex differences was insignificant (p for interaction 0.45). There was no significant difference in the relative risk of HF between men and women when both types of diabetes were combined (HR 2.22 [1.93–2.54] vs. 1.99 [1.67–2.38] respectively, p for interaction 0.80).Conclusion: Diabetes is associated with increased risks of death and heart failure, and there was no difference in relative risk according to sex.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Reinikainen, JaakkoDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare (THL), Helsinki, Finland
(författare)
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Andersson, Jonas,1977-Umeå universitet,Institutionen för folkhälsa och klinisk medicin(Swepub:umu)jasaon96
(författare)
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Di Castelnuovo, AugustoMediterranea Cardiocentro, Naples, Italy
(författare)
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Iacoviello, LiciaDepartment of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Italy; Research Center in Epidemiology and Preventive Medicine—EPIMED, Department of Medicine and Surgery, University of Insubria, Varese, Italy
(författare)
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Jousilahti, PekkaDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare (THL), Helsinki, Finland
(författare)
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Kårhus, Line LundCenter for Clinical Research and Prevention, Copenhagen University Hospital—Bispebjerg and Frederiksberg, Copenhagen, Denmark
(författare)
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Linneberg, AllanCenter for Clinical Research and Prevention, Copenhagen University Hospital—Bispebjerg and Frederiksberg, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
(författare)
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Söderberg, StefanUmeå universitet,Institutionen för folkhälsa och klinisk medicin(Swepub:umu)stso0001
(författare)
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Tunstall-Pedoe, HughCardiovascular Epidemiology Unit, Institute of Cardiovascular Research, University of Dundee, Dundee, United Kingdom
(författare)
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Lekadir, KarimArtificial Intelligence in Medicine Lab (BCN-AIM), Departament de Matemàtiques and Informàtica, Universitat de Barcelona, Barcelona, Spain
(författare)
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Aung, NayWilliam Harvey Research Institute, NIHR Barts Biomedical Research Centre, Queen Mary University of London, Charterhouse Square, London, United Kingdom; Barts Heart Centre, St Bartholomew’s Hospital, Barts Health NHS Trust, West Smithfield, London, United Kingdom
(författare)
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Jensen, Magnus T.William Harvey Research Institute, NIHR Barts Biomedical Research Centre, Queen Mary University of London, Charterhouse Square, London, United Kingdom; Steno Diabetes Center Copenhagen, Borgmester Ib Juuls Vej 83, Herlev, Denmark
(författare)
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Kuulasmaa, KariDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare (THL), Helsinki, Finland
(författare)
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Niiranen, Teemu J.Department of Public Health and Welfare, Finnish Institute for Health and Welfare (THL), Helsinki, Finland; Department of Internal Medicine, University of Turku and Turku University Hospital, Turku, Finland
(författare)
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Petersen, Steffen E.William Harvey Research Institute, NIHR Barts Biomedical Research Centre, Queen Mary University of London, Charterhouse Square, London, United Kingdom; Barts Heart Centre, St Bartholomew’s Hospital, Barts Health NHS Trust, West Smithfield, London, United Kingdom; Health Data Research UK, London, United Kingdom; National Institute for Health and Care Research, London, United Kingdom
(författare)
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William Harvey Research Institute, NIHR Barts Biomedical Research Centre, Queen Mary University of London, Charterhouse Square, London, United Kingdom; Barts Heart Centre, St Bartholomew’s Hospital, Barts Health NHS Trust, West Smithfield, London, United KingdomDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare (THL), Helsinki, Finland
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Frontiers in Cardiovascular Medicine102297-055X
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Chadalavada, Suc ...
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Reinikainen, Jaa ...
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Andersson, Jonas ...
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Di Castelnuovo, ...
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Iacoviello, Lici ...
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Jousilahti, Pekk ...
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visa fler...
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Kårhus, Line Lun ...
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Linneberg, Allan
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Söderberg, Stefa ...
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Tunstall-Pedoe, ...
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Lekadir, Karim
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Aung, Nay
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Jensen, Magnus T ...
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Kuulasmaa, Kari
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Niiranen, Teemu ...
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Petersen, Steffe ...
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