SwePub
Sök i LIBRIS databas

  Utökad sökning

WFRF:(Quail Michael A.)
 

Sökning: WFRF:(Quail Michael A.) > Genome evolution of...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004033naa a2200469 4500
001oai:DiVA.org:uu-253524
003SwePub
008150529s2008 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2535242 URI
0247 a https://doi.org/10.1093/molbev/msn1332 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Klasson, Lisa4 aut
2451 0a Genome evolution of Wolbachia strain wPip from the Culex pipiens group.
264 c 2008-06-23
264 1b Oxford University Press (OUP),c 2008
338 a print2 rdacarrier
520 a The obligate intracellular bacterium Wolbachia pipientis strain wPip induces cytoplasmic incompatibility (CI), patterns of crossing sterility, in the Culex pipiens group of mosquitoes. The complete sequence is presented of the 1.48-Mbp genome of wPip which encodes 1386 coding sequences (CDSs), representing the first genome sequence of a B-supergroup Wolbachia. Comparisons were made with the smaller genomes of Wolbachia strains wMel of Drosophila melanogaster, an A-supergroup Wolbachia that is also a CI inducer, and wBm, a mutualist of Brugia malayi nematodes that belongs to the D-supergroup of Wolbachia. Despite extensive gene order rearrangement, a core set of Wolbachia genes shared between the 3 genomes can be identified and contrasts with a flexible gene pool where rapid evolution has taken place. There are much more extensive prophage and ankyrin repeat encoding (ANK) gene components of the wPip genome compared with wMel and wBm, and both are likely to be of considerable importance in wPip biology. Five WO-B-like prophage regions are present and contain some genes that are identical or highly similar in multiple prophage copies, whereas other genes are unique, and it is likely that extensive recombination, duplication, and insertion have occurred between copies. A much larger number of genes encode ankyrin repeat (ANK) proteins in wPip, with 60 present compared with 23 in wMel, many of which are within or close to the prophage regions. It is likely that this pattern is partly a result of expansions in the wPip lineage, due for example to gene duplication, but their presence is in some cases more ancient. The wPip genome underlines the considerable evolutionary flexibility of Wolbachia, providing clear evidence for the rapid evolution of ANK-encoding genes and of prophage regions. This host-Wolbachia system, with its complex patterns of sterility induced between populations, now provides an excellent model for unraveling the molecular systems underlying host reproductive manipulation.
650 7a NATURVETENSKAPx Biologix Mikrobiologi0 (SwePub)106062 hsv//swe
650 7a NATURAL SCIENCESx Biological Sciencesx Microbiology0 (SwePub)106062 hsv//eng
650 7a NATURVETENSKAPx Biologix Evolutionsbiologi0 (SwePub)106152 hsv//swe
650 7a NATURAL SCIENCESx Biological Sciencesx Evolutionary Biology0 (SwePub)106152 hsv//eng
650 7a NATURVETENSKAPx Biologix Bioinformatik och systembiologi0 (SwePub)106102 hsv//swe
650 7a NATURAL SCIENCESx Biological Sciencesx Bioinformatics and Systems Biology0 (SwePub)106102 hsv//eng
7001 a Walker, Thomas4 aut
7001 a Sebaihia, Mohammed4 aut
7001 a Sanders, Mandy J4 aut
7001 a Quail, Michael A4 aut
7001 a Lord, Angela4 aut
7001 a Sanders, Susanne4 aut
7001 a Earl, Julie4 aut
7001 a O'Neill, Scott L4 aut
7001 a Thomson, Nicholas4 aut
7001 a Sinkins, Steven P4 aut
7001 a Parkhill, Julian4 aut
7730 t Molecular biology and evolutiond : Oxford University Press (OUP)g 25:9, s. 1877-87q 25:9<1877-87x 0737-4038x 1537-1719
8564 u https://academic.oup.com/mbe/article-pdf/25/9/1877/4124299/msn133.pdf
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-253524
8564 8u https://doi.org/10.1093/molbev/msn133

Hitta via bibliotek

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy