SwePub
Sök i LIBRIS databas

  Extended search

WFRF:(Raininko Raili)
 

Search: WFRF:(Raininko Raili) > (2015-2019) > Incomplete hippocam...

Incomplete hippocampal inversion in patients with focal epilepsy without known etiology and focal MRI abnormalities.

Bajic, Dragan (author)
Uppsala universitet,Radiologi
Kumlien, Eva (author)
Uppsala universitet,Neurologi
Raininko, Raili (author)
Uppsala universitet,Radiologi
 (creator_code:org_t)
Springer, 2016
2016
English.
In: Neuroradiology Vol 58: Suppl.1. - : Springer. ; , s. S21-
  • Conference paper (peer-reviewed)
Abstract Subject headings
Close  
  • Incomplete hippocampal inversion in patients with focal epilepsy without known etiology and focal MRI abnormalitiesPURPOSE: Incomplete hippocampal inversion (IHI) is more common in patients with epilepsy than in subjects without epilepsy but is probably not an etiological factor. IHI frequency varies in different types of epilepsy. Our purpose was to evaluate the hippocampi of patients having focal epilepsy with unknown etiology and without focal abnormalities on MRI (EPue).METHODS: MRIs of 58 patients with EPue and 147 neurologically healthy controls were evaluated. Hippocampal volumetry could be performed in 54 of the patients. 47 controls, preferably those having IHI, were chosen for volumetry. The findings were compared with seizure semiology and EEG findings.RESULTS: 30/58 patients (52%) had IHI (18 left, 12 bilateral). 28/147 controls (19%) had IHI (20 left, 8 bilateral) (p<0.001). In subjects studied with volumetry, 27/54 patients (50%) and 23/47 selected controls (49%) had IHI. In patients, IHI was found on the left in 15 and bilaterally in 12. In controls, the numbers were 16 and 5, respectively. The left hippocampus was smaller in 48 patients and in 46 controls.  Asymmetry index (AI) was >0.10 in 16 patients (30%) and in 3 controls (6.5%) (p<0.01).  Among 10 patients having IHI and AI >0.10, six had temporal lobe semiology. One of them had bilateral IHI, 5 had IHI on the left. EEG foci were ipsilateral to IHI in 3, contralateral in 2.CONCLUSIONS: IHI was significantly more common in EPue patients than in controls. Hippocampal volume asymmetry was more prominent in the patients. Temporal semiology and EEG focus were not obviously related to IHI.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)

Keyword

Radiologi
Radiology

Publication and Content Type

ref (subject category)
kon (subject category)

To the university's database

Find more in SwePub

By the author/editor
Bajic, Dragan
Kumlien, Eva
Raininko, Raili
About the subject
MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Clinical Medicin ...
and Radiology Nuclea ...
Articles in the publication
By the university
Uppsala University

Search outside SwePub

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view