SUPERIOR SVG: no touch saphenous harvesting to improve patency following coronary bypass grafting (a multi-Centre randomized control trial, NCT01047449)

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Fältnamn	Indikatorer	Metadata
000		07022naa a2200781 4500
001		oai:gup.ub.gu.se/280898
003		SwePub
008		240528s2019 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:DiVA.org:oru-74197
024	7	a https://gup.ub.gu.se/publication/2808982 URI
024	7	a https://doi.org/10.1186/s13019-019-0887-x2 DOI
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-741972 URI
040		a (SwePub)gud (SwePub)oru
041		a eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Deb, S.u Sunnybrook Health Sciences Centre, Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada4 aut
245	1 0	a SUPERIOR SVG: no touch saphenous harvesting to improve patency following coronary bypass grafting (a multi-Centre randomized control trial, NCT01047449)
264		c 2019-05-02
264	1	b Springer Science and Business Media LLC,c 2019
500		a Funding Agencies:Heart and Stroke Foundation of Canada 7092 Canadian Institutes of Health Research Centre for Trials Internationally (CANNeCTIN)
520		a BackgroundSingle centre studies support No Touch (NT) saphenous vein graft (SVG) harvesting technique. The primary objective of the SUPERIOR SVG study was to determine whether NT versus conventional (CON) SVG harvesting was associated with improved SVG patency 1year after coronary artery bypass grafting surgery (CABG).MethodsAdults undergoing isolated CABG with at least 1 SVG were eligible. CT angiography was performed 1-year post CABG. Leg adverse events were assessed with a questionnaire. A systematic review was performed for published NT graft patency studies and results aggregated including the SUPERIOR study results.ResultsTwo hundred and-fifty patients were randomized across 12-centres (NT 127 versus CON 123 patients). The primary outcome (study SVG occlusion or cardiovascular (CV) death) was not significantly different in NT versus CON (NT: 7/127 (5.5%), CON 13/123 (10.6%), p=0.15). Similarly, the proportion of study SVGs with significant stenosis or total occlusion was not significantly different between groups (NT: 8/102 (7.8%), CON: 16/107 (15.0%), p=0.11). Vein harvest site infection was more common in the NT patients 1month postoperatively (23.3% vs 9.5%, p<0.01). Including this study's results, in a meta-analysis, NT was associated with a significant reduction in SVG occlusion, Odds Ratio 0.49, 95% Confidence Interval 0.29-0.82, p=0.007 in 3 randomized and 1 observational study at 1year postoperatively.ConclusionsThe NT technique was not associated with improved patency of SVGs at 1-year following CABG while early vein harvest infection was increased. The aggregated data is supportive of an important reduction of SVG occlusion at 1year with NT harvesting.Trial registrationNCT01047449.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng
653		a No touch atraumatic saphenous vein graft harvesting
653		a Conventional open
653		a saphenous vein graft harvesting
653		a Endoscopic saphenous vein graft
653		a harvesting
653		a Multi-centred randomized controlled trial
653		a Coronary artery
653		a bypass grafting surgery
653		a Graft patency
653		a Major adverse cardiac and
653		a cerebrovascular outcomes
653		a internal-thoracic-artery
653		a pedicled vein grafts
653		a surrounding tissue
653		a surgery
653		a atherosclerosis
653		a progression
653		a Conventional open saphenous vein graft harvesting
700	1	a Singh, S. K.u Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA4 aut
700	1	a de Souza, Domingos Ramos,d 1954-u Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Cardiothoracic and Vascular Surgery4 aut0 (Swepub:oru)dra
700	1	a Chu, M. W. A.u Department of Surgery, Western University, London Health Sciences Centre, London, Canada4 aut
700	1	a Whitlock, R.u Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Canada4 aut
700	1	a Meyer, S. R.u Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Canada4 aut
700	1	a Verma, S.u St. Michael's Hospital, Toronto, Canada4 aut
700	1	a Jeppsson, Anders,d 1960u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden4 aut0 (Swepub:gu)xjepan
700	1	a Al-Saleh, A.u McMaster University, Hamilton, Canada4 aut
700	1	a Brady, K.u Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Canada4 aut
700	1	a Rao-Melacini, P.u Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Canada4 aut
700	1	a Belley-Cote, E. P.u Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Canada4 aut
700	1	a Tam, D. Y.u Sunnybrook Health Sciences Centre, Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada4 aut
700	1	a Devereaux, P. J.u Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Canada4 aut
700	1	a Novick, R. J.u University of Calgary and Foothills Medical Centre, Calgary, Canada4 aut
700	1	a Fremes, S. E.u Sunnybrook Health Sciences Centre, Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada4 aut
700	1	a Super Svg Study Investigators, Super Svg Study Investigators4 aut
710	2	a Sunnybrook Health Sciences Centre, Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canadab Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA4 org
773	0	t Journal of Cardiothoracic Surgeryd : Springer Science and Business Media LLCg 14q 14x 1749-8090
856	4	u https://cardiothoracicsurgery.biomedcentral.com/track/pdf/10.1186/s13019-019-0887-x
856	4	u https://doi.org/10.1186/s13019-019-0887-xy Fulltext
856	4 8	u https://gup.ub.gu.se/publication/280898
856	4 8	u https://doi.org/10.1186/s13019-019-0887-x
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-74197

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Av författaren/redakt...: Deb, S.; Singh, S. K.; de Souza, Doming ...; Chu, M. W. A.; Whitlock, R.; Meyer, S. R.; visa fler...; Verma, S.; Jeppsson, Anders ...; Al-Saleh, A.; Brady, K.; Rao-Melacini, P.; Belley-Cote, E. ...; Tam, D. Y.; Devereaux, P. J.; Novick, R. J.; Fremes, S. E.; Super Svg Study ...; visa färre...

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