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FältnamnIndikatorerMetadata
00009128naa a2200973 4500
001oai:DiVA.org:umu-168771
003SwePub
008200310s2020 | |||||||||||000 ||eng|
009oai:DiVA.org:uu-424407
009oai:prod.swepub.kib.ki.se:143025282
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1687712 URI
0247 a https://doi.org/10.1002/ijc.328922 DOI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4244072 URI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1430252822 URI
040 a (SwePub)umud (SwePub)uud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Schoemaker, Minouk J.u Inst Canc Res, Div Genet & Epidemiol, London, England.4 aut
2451 0a Adult weight change and premenopausal breast cancer risk :b A prospective pooled analysis of data from 628,463 women
264 c 2020-02-15
264 1b John Wiley & Sons,c 2020
338 a electronic2 rdacarrier
520 a Early-adulthood body size is strongly inversely associated with risk of premenopausal breast cancer. It is unclear whether subsequent changes in weight affect risk. We pooled individual-level data from 17 prospective studies to investigate the association of weight change with premenopausal breast cancer risk, considering strata of initial weight, timing of weight change, other breast cancer risk factors and breast cancer subtype. Hazard ratios (HR) and 95% confidence intervals (CI) were obtained using Cox regression. Among 628,463 women, 10,886 were diagnosed with breast cancer before menopause. Models adjusted for initial weight at ages 18-24 years and other breast cancer risk factors showed that weight gain from ages 18-24 to 35-44 or to 45-54 years was inversely associated with breast cancer overall (e.g., HR per 5 kg to ages 45-54: 0.96, 95% CI: 0.95-0.98) and with oestrogen-receptor(ER)-positive breast cancer (HR per 5 kg to ages 45-54: 0.96, 95% CI: 0.94-0.98). Weight gain from ages 25-34 was inversely associated with ER-positive breast cancer only and weight gain from ages 35-44 was not associated with risk. None of these weight gains were associated with ER-negative breast cancer. Weight loss was not consistently associated with overall or ER-specific risk after adjusting for initial weight. Weight increase from early-adulthood to ages 45-54 years is associated with a reduced premenopausal breast cancer risk independently of early-adulthood weight. Biological explanations are needed to account for these two separate factors.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
653 a breast neoplasms
653 a premenopause
653 a body weight changes
653 a risk factors
653 a cohort studies
7001 a Nichols, Hazel B.u Univ N Carolina, Dept Epidemiol, Gillings Sch Global Publ Hlth, Chapel Hill, NC 27515 USA.4 aut
7001 a Wright, Lauren B.u Inst Canc Res, Div Genet & Epidemiol, London, England.,Univ Pisa, Dept Clin & Expt Med, Pisa, Italy.4 aut
7001 a Brook, Mark N.u Inst Canc Res, Div Genet & Epidemiol, London, England.4 aut
7001 a Jones, Michael E.u Inst Canc Res, Div Genet & Epidemiol, London, England.4 aut
7001 a O'Brien, Katie M.u NIEHS, Biostat & Computat Biol Branch, NIH, Durham, NC USA.4 aut
7001 a Adami, Hans-Olovu Karolinska Institutet4 aut
7001 a Baglietto, Laura4 aut
7001 a Bernstein, Leslieu Beckman Res Inst City Hope, Dept Populat Sci, Duarte, CA USA.4 aut
7001 a Bertrand, Kimberly A.u Boston Univ, Slone Epidemiol Ctr, Boston, MA 02215 USA.4 aut
7001 a Boutron-Ruault, Marie-Christineu Univ Pisa, Dept Clin & Expt Med, Pisa, Italy.4 aut
7001 a Chen, Yuu NYU, Sch Med, Dept Populat Hlth, New York, NY USA.;NYU, Sch Med, Perlmutter Canc Ctr, New York, NY USA.4 aut
7001 a Connor, Avonne E.u Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA.;Johns Hopkins Sidney Kimmel Comprehens Canc Ctr, Baltimore, MD USA.4 aut
7001 a Dossus, Laureu Int Agcy Res Canc, Nutr & Metab Sect, Lyon, France.4 aut
7001 a Eliassen, A. Heatheru Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA USA.;Brigham & Womens Hosp, Dept Med, Channing Div Network Med, 75 Francis St, Boston, MA 02115 USA.;Harvard Med Sch, Boston, MA 02115 USA.4 aut
7001 a Giles, Graham G.u Canc Council Victoria, Canc Epidemiol & Intelligence Div, Melbourne, Vic, Australia.;Univ Melbourne, Ctr Epidemiol & Biostat, Sch Populat & Global Hlth, Melbourne, Vic, Australia.4 aut
7001 a Gram, Inger T.u Univ Tromso UiT, Dept Community Med, Fac Hlth Sci, Tromso, Norway.4 aut
7001 a Hankinson, Susan E.u Univ Massachusetts, Dept Biostat & Epidemiol, Sch Publ Hlth & Hlth Sci, Amherst, MA 01003 USA.4 aut
7001 a Kaaks, Rudolfu DKFZ, Div Canc Epidemiol, Heidelberg, Germany.4 aut
7001 a Key, Timothy J.u Univ Oxford, Nuffield Dept Populat Hlth, Oxford, England.4 aut
7001 a Kirsh, Victoria A.u Ontario Inst Canc Res, Toronto, ON, Canada.4 aut
7001 a Kitahara, Cari M.u NCI, Radiat Epidemiol Branch, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.4 aut
7001 a Larsson, Susanna C.u Karolinska Institutet4 aut
7001 a Linet, Marthau NCI, Radiat Epidemiol Branch, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.4 aut
7001 a Ma, Huiyanu Beckman Res Inst City Hope, Dept Populat Sci, Duarte, CA USA.4 aut
7001 a Milne, Roger L.u Canc Council Victoria, Canc Epidemiol & Intelligence Div, Melbourne, Vic, Australia.;Univ Melbourne, Ctr Epidemiol & Biostat, Sch Populat & Global Hlth, Melbourne, Vic, Australia.4 aut
7001 a Ozasa, Kotarou Radiat Effects Res Fdn, Hiroshima, Japan.4 aut
7001 a Palmer, Julie R.u Boston Univ, Slone Epidemiol Ctr, Boston, MA 02215 USA.4 aut
7001 a Riboli, Eliou Imperial Coll, Sch Publ Hlth, London, England.4 aut
7001 a Rohan, Thomas E.u Albert Einstein Coll Med, Bronx, NY 10467 USA.4 aut
7001 a Sacerdote, Carlottau Citta Salute & Sci Univ Hosp, Unit Canc Epidemiol, Turin, Italy.;Ctr Canc Prevent CPO, Turin, Italy.4 aut
7001 a Sadakane, Atsukou Radiat Effects Res Fdn, Hiroshima, Japan.4 aut
7001 a Sund, Malinu Umeå universitet,Kirurgi,Umeå Univ, Dept Surg & Perioperat Sci, Umeå, Sweden.4 aut0 (Swepub:umu)masu0021
7001 a Tamimi, Rulla M.u Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA USA.;Brigham & Womens Hosp, Dept Med, Channing Div Network Med, 75 Francis St, Boston, MA 02115 USA.;Harvard Med Sch, Boston, MA 02115 USA.4 aut
7001 a Trichopoulou, Antoniau Hellen Hlth Fdn, Athens, Greece.4 aut
7001 a Ursin, Giskeu Inst Populat Based Canc Res, Canc Registry Norway, Oslo, Norway.;Univ Oslo, Inst Basic Med Sci, Oslo, Norway.;Univ Southern Calif, Dept Prevent Med, Los Angeles, CA 90007 USA.4 aut
7001 a Visvanathan, Kalau Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA.;Johns Hopkins Sch Med, Baltimore, MD USA.4 aut
7001 a Weiderpass, Elisabeteu WHO, IARC, Lyon, France.4 aut
7001 a Willett, Walter C.u Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA USA.;Brigham & Womens Hosp, Dept Med, Channing Div Network Med, 75 Francis St, Boston, MA 02115 USA.;Harvard Med Sch, Boston, MA 02115 USA.4 aut
7001 a Wolk, Alicjau Karolinska Institutet,Uppsala universitet,Ortopedi,Karolinska Inst, Inst Environm Med, Stockholm, Sweden4 aut0 (Swepub:uu)alwol516
7001 a Zeleniuch-Jacquotte, Anneu NYU, Sch Med, Dept Populat Hlth, New York, NY USA.;NYU, Sch Med, Perlmutter Canc Ctr, New York, NY USA.4 aut
7001 a Sandler, Dale P.u NIEHS, Epidemiol Branch, NIH, Durham, NC USA.4 aut
7001 a Swerdlow, Anthony J.u Inst Canc Res, Div Genet & Epidemiol, London, England.;Inst Canc Res, Div Breast Canc Res, London, England.4 aut
7102 a Inst Canc Res, Div Genet & Epidemiol, London, England.b Univ N Carolina, Dept Epidemiol, Gillings Sch Global Publ Hlth, Chapel Hill, NC 27515 USA.4 org
7730 t International Journal of Cancerd : John Wiley & Sonsg 147:5, s. 1306-1314q 147:5<1306-1314x 0020-7136x 1097-0215
8564 u https://doi.org/10.1002/ijc.32892y Fulltext
8564 u https://umu.diva-portal.org/smash/get/diva2:1413371/FULLTEXT03.pdfx primaryx Raw objecty fulltext:print
8564 u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijc.32892
8564 u https://uu.diva-portal.org/smash/get/diva2:1500116/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-168771
8564 8u https://doi.org/10.1002/ijc.32892
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-424407
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:143025282

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