Sökning: WFRF:(Lewis Sarah J.) > Identification of f...
Fältnamn | Indikatorer | Metadata |
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000 | 05808naa a2201405 4500 | |
001 | oai:DiVA.org:umu-46221 | |
003 | SwePub | |
008 | 110829s2010 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-462212 URI |
024 | 7 | a https://doi.org/10.1126/science.11983742 DOI |
040 | a (SwePub)umu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Roy, Sushmita4 aut |
245 | 1 0 | a Identification of functional elements and regulatory circuits by Drosophila modENCODE. |
264 | 1 | b American Association for the Advancement of Science (AAAS),c 2010 |
338 | a print2 rdacarrier | |
520 | a To gain insight into how genomic information is translated into cellular and developmental programs, the Drosophila model organism Encyclopedia of DNA Elements (modENCODE) project is comprehensively mapping transcripts, histone modifications, chromosomal proteins, transcription factors, replication proteins and intermediates, and nucleosome properties across a developmental time course and in multiple cell lines. We have generated more than 700 data sets and discovered protein-coding, noncoding, RNA regulatory, replication, and chromatin elements, more than tripling the annotated portion of the Drosophila genome. Correlated activity patterns of these elements reveal a functional regulatory network, which predicts putative new functions for genes, reveals stage- and tissue-specific regulators, and enables gene-expression prediction. Our results provide a foundation for directed experimental and computational studies in Drosophila and related species and also a model for systematic data integration toward comprehensive genomic and functional annotation. | |
700 | 1 | a Ernst, Jason4 aut |
700 | 1 | a Kharchenko, Peter V4 aut |
700 | 1 | a Kheradpour, Pouya4 aut |
700 | 1 | a Negre, Nicolas4 aut |
700 | 1 | a Eaton, Matthew L4 aut |
700 | 1 | a Landolin, Jane M4 aut |
700 | 1 | a Bristow, Christopher A4 aut |
700 | 1 | a Ma, Lijia4 aut |
700 | 1 | a Lin, Michael F4 aut |
700 | 1 | a Washietl, Stefan4 aut |
700 | 1 | a Arshinoff, Bradley I4 aut |
700 | 1 | a Ay, Ferhat4 aut |
700 | 1 | a Meyer, Patrick E4 aut |
700 | 1 | a Robine, Nicolas4 aut |
700 | 1 | a Washington, Nicole L4 aut |
700 | 1 | a Di Stefano, Luisa4 aut |
700 | 1 | a Berezikov, Eugene4 aut |
700 | 1 | a Brown, Christopher D4 aut |
700 | 1 | a Candeias, Rogerio4 aut |
700 | 1 | a Carlson, Joseph W4 aut |
700 | 1 | a Carr, Adrian4 aut |
700 | 1 | a Jungreis, Irwin4 aut |
700 | 1 | a Marbach, Daniel4 aut |
700 | 1 | a Sealfon, Rachel4 aut |
700 | 1 | a Tolstorukov, Michael Y4 aut |
700 | 1 | a Will, Sebastian4 aut |
700 | 1 | a Alekseyenko, Artyom A4 aut |
700 | 1 | a Artieri, Carlo4 aut |
700 | 1 | a Booth, Benjamin W4 aut |
700 | 1 | a Brooks, Angela N4 aut |
700 | 1 | a Dai, Qi4 aut |
700 | 1 | a Davis, Carrie A4 aut |
700 | 1 | a Duff, Michael O4 aut |
700 | 1 | a Feng, Xin4 aut |
700 | 1 | a Gorchakov, Andrey A4 aut |
700 | 1 | a Gu, Tingting4 aut |
700 | 1 | a Henikoff, Jorja G4 aut |
700 | 1 | a Kapranov, Philipp4 aut |
700 | 1 | a Li, Renhua4 aut |
700 | 1 | a MacAlpine, Heather K4 aut |
700 | 1 | a Malone, John4 aut |
700 | 1 | a Minoda, Aki4 aut |
700 | 1 | a Nordman, Jared4 aut |
700 | 1 | a Okamura, Katsutomo4 aut |
700 | 1 | a Perry, Marc4 aut |
700 | 1 | a Powell, Sara K4 aut |
700 | 1 | a Riddle, Nicole C4 aut |
700 | 1 | a Sakai, Akiko4 aut |
700 | 1 | a Samsonova, Anastasia4 aut |
700 | 1 | a Sandler, Jeremy E4 aut |
700 | 1 | a Schwartz, Yuri Bu Rutgers University, New Jersey, USA4 aut0 (Swepub:umu)yusc0002 |
700 | 1 | a Sher, Noa4 aut |
700 | 1 | a Spokony, Rebecca4 aut |
700 | 1 | a Sturgill, David4 aut |
700 | 1 | a van Baren, Marijke4 aut |
700 | 1 | a Wan, Kenneth H4 aut |
700 | 1 | a Yang, Li4 aut |
700 | 1 | a Yu, Charles4 aut |
700 | 1 | a Feingold, Elise4 aut |
700 | 1 | a Good, Peter4 aut |
700 | 1 | a Guyer, Mark4 aut |
700 | 1 | a Lowdon, Rebecca4 aut |
700 | 1 | a Ahmad, Kami4 aut |
700 | 1 | a Andrews, Justen4 aut |
700 | 1 | a Berger, Bonnie4 aut |
700 | 1 | a Brenner, Steven E4 aut |
700 | 1 | a Brent, Michael R4 aut |
700 | 1 | a Cherbas, Lucy4 aut |
700 | 1 | a Elgin, Sarah C R4 aut |
700 | 1 | a Gingeras, Thomas R4 aut |
700 | 1 | a Grossman, Robert4 aut |
700 | 1 | a Hoskins, Roger A4 aut |
700 | 1 | a Kaufman, Thomas C4 aut |
700 | 1 | a Kent, William4 aut |
700 | 1 | a Kuroda, Mitzi I4 aut |
700 | 1 | a Orr-Weaver, Terry4 aut |
700 | 1 | a Perrimon, Norbert4 aut |
700 | 1 | a Pirrotta, Vincenzo4 aut |
700 | 1 | a Posakony, James W4 aut |
700 | 1 | a Ren, Bing4 aut |
700 | 1 | a Russell, Steven4 aut |
700 | 1 | a Cherbas, Peter4 aut |
700 | 1 | a Graveley, Brenton R4 aut |
700 | 1 | a Lewis, Suzanna4 aut |
700 | 1 | a Micklem, Gos4 aut |
700 | 1 | a Oliver, Brian4 aut |
700 | 1 | a Park, Peter J4 aut |
700 | 1 | a Celniker, Susan E4 aut |
700 | 1 | a Henikoff, Steven4 aut |
700 | 1 | a Karpen, Gary H4 aut |
700 | 1 | a Lai, Eric C4 aut |
700 | 1 | a MacAlpine, David M4 aut |
700 | 1 | a Stein, Lincoln D4 aut |
700 | 1 | a White, Kevin P4 aut |
700 | 1 | a Kellis, Manolis4 aut |
710 | 2 | a Rutgers University, New Jersey, USA4 org |
773 | 0 | t Science (New York, N.Y.)d : American Association for the Advancement of Science (AAAS)g 330:6012, s. 1787-1797q 330:6012<1787-1797x 1095-9203x 0036-8075 |
856 | 4 | u https://dspace.mit.edu/bitstream/1721.1/79870/2/Berger_Identification%20of%20functional.pdf |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-46221 |
856 | 4 8 | u https://doi.org/10.1126/science.1198374 |
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