Sökning: swepub > Management and outc...
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000 | 07424naa a2200805 4500 | |
001 | oai:DiVA.org:oru-77694 | |
003 | SwePub | |
008 | 191031s2019 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:umu-165088 | |
009 | oai:prod.swepub.kib.ki.se:231663405 | |
009 | oai:prod.swepub.kib.ki.se:142186667 | |
009 | oai:DiVA.org:liu-162068 | |
009 | oai:lup.lub.lu.se:799c1672-08bb-43f1-926a-24bca5eedc74 | |
009 | oai:gup.ub.gu.se/285806 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-776942 URI |
024 | 7 | a https://doi.org/10.1080/21681805.2019.16815042 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1650882 URI |
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024 | 7 | a https://gup.ub.gu.se/publication/2858062 URI |
040 | a (SwePub)orud (SwePub)umud (SwePub)kid (SwePub)kid (SwePub)liud (SwePub)lud (SwePub)gu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Abdul-Sattar Aljabery, Firasu Linköping University,Linköpings universitet,Institutionen för klinisk och experimentell medicin,Medicinska fakulteten,Region Östergötland, Urologiska kliniken i Östergötland4 aut0 (Swepub:liu)firab05 |
245 | 1 0 | a Management and outcome of muscle-invasive bladder cancer with clinical lymph node metastases. A nationwide population-based study in the bladder cancer data base Sweden (BladderBaSe) |
264 | c 2019-10-30 | |
264 | 1 | b Informa Healthcare,c 2019 |
338 | a print2 rdacarrier | |
500 | a Funding Agencies|Swedish Cancer SocietySwedish Cancer Society [CAN 2016/470, CAN 2017/278] | |
520 | a Purpose: To investigate the clinical management and outcome of patients with muscle-invasive bladder cancer with clinical lymph node involvement, using longitudinal nationwide population-based data.Methods: In the Bladder Cancer Data Base Sweden (BladderBaSe), treatment and survival in patients with urinary bladder cancer clinical stage T2-T4 N + M0 diagnosed between 1997 and 2014 was investigated. Patients´ characteristics were studied in relation to TNM classification, curative or palliative treatment, cancer-specific (CSS) and overall survival (OS). Age at diagnosis was categorised as ≤60, 61-70, 71-80 and >80 years, and time periods were stratified as follows: 1997-2001, 2002-2005, 2006-2010 and 2011-2014.Results: There were 786 patients (72% males) with a median age of 71 years (interquartile range = 64-79 years). The proportion of patients with high comorbidity increased over time. Despite similar low comorbidity, curative treatment was given to 44% and to 70% of those in older (>70 years) and younger age groups, respectively. Curative treatment decreased over time, but chemotherapy and cystectomy increased to 25% during the last time period. Patients with curative treatment had better survival compared to those with palliative treatment, both regarding CSS and OS in the whole cohort and in all age groups.Conclusions: The low proportion of older patients undergoing treatment with curative intent, despite no or limited comorbidity, indicates missed chances of treatment with curative intent. The reasons for an overall decrease in curative treatment over time need to be analysed and the challenge of coping with an increasing proportion of node-positive patients with clinically significant comorbidity needs to be met. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Urologi och njurmedicin0 (SwePub)302142 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Urology and Nephrology0 (SwePub)302142 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
653 | a Bladder cancer | |
653 | a cohort study | |
653 | a lymph node metastasis | |
653 | a management | |
653 | a outcome | |
653 | a Bladder cancer | |
653 | a cohort study | |
653 | a lymph node metastasis | |
653 | a management | |
653 | a outcome | |
700 | 1 | a Liedberg, Fredriku Lund University,Lunds universitet,Urologi - blåscancer, Malmö,Forskargrupper vid Lunds universitet,Urology - urothelial cancer, Malmö,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)urok-fli |
700 | 1 | a Häggström, Christelu Uppsala University,Umeå University,Umeå universitet,Enheten för biobanksforskning,Department of Surgical Sciences, Uppsala University, Uppsala, Sweden; Department of Biobank Research, Umeå University, Umeå, Sweden,Uppsala Univ, Sweden; Umea Univ, Sweden4 aut0 (Swepub:umu)chlham02 |
700 | 1 | a Ströck, Vivekau Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för urologi,Institute of Clinical Sciences, Department of Urology4 aut0 (Swepub:gu)xstrvi |
700 | 1 | a Hosseini, Abolfazlu Department of Pelvic Cancer, Karolinska University Hospital, Stockholm, Sweden,Karolinska Univ Hosp, Sweden4 aut |
700 | 1 | a Gårdmark, Trulsu Karolinska Institutet,Karolinska Inst, Sweden,Danderyd Hospital4 aut |
700 | 1 | a Sherif, Amiru Umeå University,Umeå universitet,Urologi och andrologi,Department of Surgical and Perioperative Sciences, Urology and Andrology, Umeå University, Umeå, Sweden,Umea Univ, Sweden4 aut0 (Swepub:umu)amsh0008 |
700 | 1 | a Jerlström, Tomas,d 1969-u Örebro University,Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Urology,Orebro Univ, Sweden4 aut0 (Swepub:oru)tjm |
700 | 1 | a Malmström, Per-Unou Uppsala University4 aut |
700 | 1 | a Holmberg, Larsu Uppsala University,King's College London4 aut |
700 | 1 | a Hagberg, Oskaru Lund University,Lunds universitet,Urologi - blåscancer, Malmö,Forskargrupper vid Lunds universitet,Urology - urothelial cancer, Malmö,Lund University Research Groups4 aut0 (Swepub:lu)mats-oha |
700 | 1 | a Jahnson, Staffanu Linköping University,Linköpings universitet,Avdelningen för Kirurgi, Ortopedi och Onkologi,Medicinska fakulteten,Region Östergötland, Urologiska kliniken i Östergötland4 aut0 (Swepub:liu)staja74 |
710 | 2 | a Linköpings universitetb Institutionen för klinisk och experimentell medicin4 org |
773 | 0 | t Scandinavian journal of urologyd : Informa Healthcareg 53:5, s. 332-338q 53:5<332-338x 2168-1805x 2168-1813 |
856 | 4 | u http://dx.doi.org/10.1080/21681805.2019.1681504y FULLTEXT |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-77694 |
856 | 4 8 | u https://doi.org/10.1080/21681805.2019.1681504 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-165088 |
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856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-162068 |
856 | 4 8 | u https://lup.lub.lu.se/record/799c1672-08bb-43f1-926a-24bca5eedc74 |
856 | 4 8 | u https://gup.ub.gu.se/publication/285806 |
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