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  • Cederlof, M.Karolinska Institutet (författare)

Language and mathematical problems as precursors of psychotic-like experiences and juvenile mania symptoms

  • Artikel/kapitelEngelska2014

Förlag, utgivningsår, omfång ...

  • Stockholm :Karolinska Institutet, Dept of Medical Epidemiology and Biostatistics,2014

Nummerbeteckningar

  • LIBRIS-ID:oai:lup.lub.lu.se:4f159386-de35-4e9c-a283-b47ff8fbe12c
  • ISSN:0033-2917
  • 10616/42107hdl
  • https://lup.lub.lu.se/record/4558499URI
  • https://doi.org/10.1017/S0033291713002018DOI
  • http://hdl.handle.net/10616/42107URI
  • https://gup.ub.gu.se/publication/182503URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:129114992URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

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Klassifikation

  • Ämneskategori:art swepub-publicationtype
  • Ämneskategori:ref swepub-contenttype

Anmärkningar

  • Background. Psychotic-like experiences (PLEs) and juvenile mania in adolescence index risk for severe psychopathology in adulthood. The importance of childhood problems with communication, reading, speech and mathematics for the development of PLEs and juvenile mania is not well understood. Method. Through the Child and Adolescent Twin Study in Sweden, we identified 5812 children. The parents were interviewed about their children's development at age 9 or 12 years. At age 15 or 18 years, children and parents completed questionnaires targeting current PLEs and juvenile mania symptoms. Logistic regressions were used to assess associations between problems with communication, reading, speech and mathematics and PLEs/juvenile mania symptoms. To evaluate the relative importance of genes and environment in these associations, we used bivariate twin analyses based on structural equation models. Results. Children with parent-endorsed childhood problems with communication, reading and mathematics had an increased risk of developing auditory hallucinations and parental-reported juvenile mania symptoms in adolescence. The most consistent finding was that children with childhood problems with communication, reading and mathematics had an increased risk of developing auditory hallucinations [for example, the risk for self-reported auditory hallucinations at age 15 was increased by 96% for children with communication problems: OR (odds ratio) 1.96, 95% confidence interval (CI) 1.33-2.88]. The twin analyses showed that genetic effects accounted for the increased risk of PLEs and juvenile mania symptoms among children with communication problems. Conclusions. Childhood problems with communication, reading and mathematics predict PLEs and juvenile mania symptoms in adolescence. Similar to the case for schizophrenia and bipolar disorder, PLEs and juvenile mania may share genetic aetiological factors.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Ostberg, P.Karolinska Institutet (författare)
  • Pettersson, E.Karolinska Institutet (författare)
  • Anckarsäter, HenrikGothenburg University,Göteborgs universitet,Lund University,Lunds universitet,Rättspsykiatri, Malmö,Forskargrupper vid Lunds universitet,Forensic Psychiatry, Malmö,Lund University Research Groups,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Centrum för etik, juridik och mental hälsa,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry,Centre for Ethics, Law, and Mental Health(Swepub:gu)xanche (författare)
  • Gumpert, C.Karolinska Institutet (författare)
  • Lundström, SebastianGothenburg University,Göteborgs universitet,Centrum för etik, juridik och mental hälsa,Gillbergcentrum,Centre for Ethics, Law, and Mental Health,Gillberg Neuropsychiatry Centre(Swepub:gu)xluseb (författare)
  • Lichtenstein, P.Karolinska Institutet (författare)
  • Karolinska InstitutetRättspsykiatri, Malmö (creator_code:org_t)
  • Karolinska Institutet
  • Karolinska Institutet

Sammanhörande titlar

  • Ingår i:Psychological MedicineStockholm : Karolinska Institutet, Dept of Medical Epidemiology and Biostatistics44:6, s. 1293-13021469-8978
  • Ingår i:Psychological MedicineStockholm : Karolinska Institutet, Dept of Medical Epidemiology and Biostatistics44:6, s. 1293-13020033-2917

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