Geographic variation in hemocyte diversity and phagocytic propensity shows a diffuse genomic signature in the green veined white butterfly

Keehnen, Naomi (author): Stockholms universitet,Avdelningen för populationsgenetik

Fors, Lisa (author): Stockholms universitet,Avdelningen för populationsgenetik

Järver, Peter (author): Stockholms universitet,Institutionen för molekylär biovetenskap, Wenner-Grens institut

Spetz, Anna-Lena (author): Stockholms universitet,Institutionen för molekylär biovetenskap, Wenner-Grens institut

Nylin, Sören (author): Stockholms universitet,Avdelningen för zoologisk ekologi

Theopold, Ulrich (author): Stockholms universitet,Institutionen för molekylär biovetenskap, Wenner-Grens institut

Wheat, Christopher (author): Stockholms universitet,Avdelningen för populationsgenetik

(creator_code:org_t)

Related links:: https://www.biorxiv....; show more...; https://urn.kb.se/re...; https://doi.org/10.1...; show less...

Abstract Subject headings

Insects rely on their innate immune system to successfully mediate complex interactions with their internal microbiota, as well as the microbes present in the environment. Given the variation in microbes across habitats, the challenges to respond to them is likely to result in local adaptation in the immune system. Here we focus upon phagocytosis, a mechanism by which pathogens and foreign particles are engulfed in order to be contained, killed and processed for antigen presentation. We investigated the phenotypic and genetic variation related to phagocytosis, in two allopatric populations of the butterfly Pieris napi. We found that the populations differ in their hemocyte composition, and overall phagocytic capability, driven by the increased phagocytic propensity of each cell type. However, no evidence for divergence in phagocytosis-related genes was observed, though an enrichment of genes involved in glutamine metabolism was found, which have recently been linked to immune cell differentiation in mammals.

By the author/editor: Keehnen, Naomi; Fors, Lisa; Järver, Peter; Spetz, Anna-Lena; Nylin, Sören; Theopold, Ulrich; show more...; Wheat, Christoph ...; show less...

About the subject

NATURAL SCIENCES: NATURAL SCIENCES; and Biological Scien ...; and Evolutionary Bio ...

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