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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 22866naa a2201849 4500 | |
| 001 | oai:DiVA.org:uu-312625 | |
| 003 | SwePub | |
| 008 | 170112s2016 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3126252 URI |
| 024 | 7 | a https://doi.org/10.1073/pnas.16112431132 DOI |
| 040 | a (SwePub)uu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Schumann, Gunteru Kings Coll London, MRC, Inst Psychiat Psychol & Neurosci, Social Genet & Dev Psychiat Ctr, London SE5 8AF, England.4 aut |
| 245 | 1 0 | a KLB is associated with alcohol drinking, and its gene product beta-Klotho is necessary for FGF21 regulation of alcohol preference |
| 264 | c 2016-11-28 | |
| 264 | 1 | b Proceedings of the National Academy of Sciences,c 2016 |
| 338 | a print2 rdacarrier | |
| 520 | a Excessive alcohol consumption is a major public health problem worldwide. Although drinking habits are known to be inherited, few genes have been identified that are robustly linked to alcohol drinking. We conducted a genome-wide association metaanalysis and replication study among >105,000 individuals of European ancestry and identified beta-Klotho (KLB) as a locus associated with alcohol consumption (rs11940694; P = 9.2 x 10(-12)). beta-Klotho is an obligate coreceptor for the hormone FGF21, which is secreted from the liver and implicated in macronutrient preference in humans. We show that brain-specific beta-Klotho KO mice have an increased alcohol preference and that FGF21 inhibits alcohol drinking by acting on the brain. These data suggest that a liver-brain endocrine axis may play an important role in the regulation of alcohol drinking behavior and provide a unique pharmacologic target for reducing alcohol consumption. | |
| 653 | a alcohol consumption | |
| 653 | a human | |
| 653 | a beta-Klotho | |
| 653 | a FGF21 | |
| 653 | a mouse model | |
| 700 | 1 | a Liu, Chunyuu Framingham Heart Dis Epidemiol Study, Framingham, MA 01702 USA.;NHLBI, Populat Sci Branch, Div Intramural Res, Bethesda, MD 20824 USA.;Boston Univ, Sch Publ, Dept Biostat, Boston, MA 02118 USA.4 aut |
| 700 | 1 | a O'Reilly, Paulu Kings Coll London, MRC, Inst Psychiat Psychol & Neurosci, Social Genet & Dev Psychiat Ctr, London SE5 8AF, England.4 aut |
| 700 | 1 | a Gao, Heu Imperial Coll London, Dept Epidemiol & Biostat, Sch Publ Hlth, London W2 1PG, England.;Imperial Coll London, MRC, Publ Hlth England Ctr Environm & Hlth, London W2 1PG, England.4 aut |
| 700 | 1 | a Song, Parkyongu Univ Texas Southwestern Med Ctr Dallas, Dept Pharmacol, Dallas, TX 75390 USA.;Univ Texas Southwestern Med Ctr Dallas, Howard Hughes Med Inst, Dallas, TX 75390 USA.4 aut |
| 700 | 1 | a Xu, Bingu Kings Coll London, MRC, Inst Psychiat Psychol & Neurosci, Social Genet & Dev Psychiat Ctr, London SE5 8AF, England.4 aut |
| 700 | 1 | a Ruggeri, Barbarau Kings Coll London, MRC, Inst Psychiat Psychol & Neurosci, Social Genet & Dev Psychiat Ctr, London SE5 8AF, England.4 aut |
| 700 | 1 | a Amin, Najafu Erasmus MC, Genet Epidemiol Unit, Dept Epidemiol, NL-3000 CA Rotterdam, Netherlands.4 aut |
| 700 | 1 | a Jia, Tianyeu Kings Coll London, MRC, Inst Psychiat Psychol & Neurosci, Social Genet & Dev Psychiat Ctr, London SE5 8AF, England.4 aut |
| 700 | 1 | a Preis, Sarahu Boston Univ, Sch Publ, Dept Biostat, Boston, MA 02118 USA.4 aut |
| 700 | 1 | a Lepe, Marcelo Segurau Imperial Coll London, Dept Epidemiol & Biostat, Sch Publ Hlth, London W2 1PG, England.;Bayer Pharma AG, Sect Bioinformat, D-13342 Berlin, Germany.4 aut |
| 700 | 1 | a Akira, Shizuou Osaka Univ, World Premier Int Immunol Frontier Res Ctr, Microbial Dis Res Inst, Lab Host Def, Osaka 5650871, Japan.4 aut |
| 700 | 1 | a Barbieri, Caterinau San Raffaele Res Inst, Div Genet & Cell Biol, I-20132 Milan, Italy.4 aut |
| 700 | 1 | a Baumeister, Sebastianu Univ Med Greifswald, Inst Community Med, D-17475 Greifswald, Germany.;Univ Regensburg, Dept Epidemiol & Prevent Med, D-93053 Regensburg, Germany.4 aut |
| 700 | 1 | a Cauchi, Stephaneu Univ Lille 2, European Genom Inst Diabet, Lille Pasteur Inst, CNRS,UMR 8199, F-59000 Lille, France.4 aut |
| 700 | 1 | a Clarke, Toni-Kimu Univ Edinburgh, Div Psychiat, Edinburgh EH10 5HF, Midlothian, Scotland.4 aut |
| 700 | 1 | a Enroth, Stefanu Uppsala universitet,Science for Life Laboratory, SciLifeLab,Medicinsk genetik och genomik4 aut0 (Swepub:uu)stenr451 |
| 700 | 1 | a Fischer, Kristau Univ Tartu, Estonian Genome Ctr, EE-51010 Tartu, Estonia.4 aut |
| 700 | 1 | a Hallfors, Jenniu Univ Helsinki, Inst Mol Med, Helsinki 00290, Finland.4 aut |
| 700 | 1 | a Harris, Sarah E.u Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Edinburgh EH8 9JZ, Midlothian, Scotland.;Univ Edinburgh, Ctr Genom & Expt Med, Edinburgh EH4 2XU, Midlothian, Scotland.4 aut |
| 700 | 1 | a Hieber, Saskiau Friedrich Alexander Univ Erlangen Nuremberg, Dept Psychiat & Psychotherapy, D-91054 Erlangen, Germany.4 aut |
| 700 | 1 | a Hofer, Edithu Med Univ Graz, Clin Div Neurogeriatr, Dept Neurol, A-8036 Graz, Austria.;Med Univ Graz, Inst Med Informat Stat & Documentat, A-8036 Graz, Austria.4 aut |
| 700 | 1 | a Hottenga, Jouke-Janu Vrije Univ Amsterdam, Dept Biol Psychol, NL-1081 BT Amsterdam, Netherlands.;EMGO Inst Hlth & Care Res, NL-1081 BT Amsterdam, Netherlands.4 aut |
| 700 | 1 | a Johansson, Åsau Uppsala universitet,Science for Life Laboratory, SciLifeLab,Medicinsk genetik och genomik4 aut0 (Swepub:uu)asjoh108 |
| 700 | 1 | a Joshi, PeterK.u Univ Edinburgh, Usher Inst Populat Hlth Sci & Informat, Edinburgh EH8 9AG, Midlothian, Scotland.4 aut |
| 700 | 1 | a Kaartinen, Niinau Natl Inst Hlth & Welf, Helsinki 00271, Finland.4 aut |
| 700 | 1 | a Laitinen, Jaanau Finnish Inst Occupat Hlth, Quantified Employee Unit, Helsinki 00250, Finland.4 aut |
| 700 | 1 | a Lemaitre, Rozennu Univ Washington, Dept Med, Cardiovasc Hlth Res Unit, Seattle, WA 98101 USA.4 aut |
| 700 | 1 | a Loukola, Anuu Univ Helsinki, Inst Mol Med, Helsinki 00290, Finland.;Univ Helsinki, Dept Publ Hlth, FIN-00014 Helsinki, Finland.4 aut |
| 700 | 1 | a Luan, Jian'anu Univ Cambridge, Sch Clin Med, MRC, Epidemiol Unit,Inst Metab Sci, Cambridge CB2 0QQ, England.4 aut |
| 700 | 1 | a Lyytikainen, Leo-Pekkau Fimlab Labs, Dept Clin Chem, Tampere 33520, Finland.;Univ Tampere, Sch Med, Tampere 33520, Finland.4 aut |
| 700 | 1 | a Mangino, Massimou Kings Coll London, Dept Twin Res & Genet Epidemiol, London SE1 7EH, England.;Guys & St Thomas Fdn Trust, Natl Inst Hlth Res, Biomed Res Ctr, London SE1 9RT, England.4 aut |
| 700 | 1 | a Manichaikul, Aniu Univ Virginia, Ctr Publ Hlth Genom, Dept Publ Hlth Sci, Charlottesville, VA 22903 USA.;Univ Virginia, Biostat Sect, Dept Publ Hlth Sci, Charlottesville, VA 22903 USA.4 aut |
| 700 | 1 | a Mbarek, Hamdiu Vrije Univ Amsterdam, Dept Biol Psychol, NL-1081 BT Amsterdam, Netherlands.;EMGO Inst Hlth & Care Res, NL-1081 BT Amsterdam, Netherlands.4 aut |
| 700 | 1 | a Milaneschi, Yuriu Vrije Univ Amsterdam, Inst Hlth & Care Res EMGO, Inst Hlth & Care Res, Dept Psychiat,Univ Med Ctr,Geestelijke Gezondheid, NL-1081 HL Amsterdam, Netherlands.;Vrije Univ Amsterdam, Neurosci Campus Amsterdam, Univ Med Ctr, Geestelijke Gezondheids Zorg GGZ InGeest, NL-1081 HL Amsterdam, Netherlands.4 aut |
| 700 | 1 | a Moayyeri, Alirezau Imperial Coll London, Dept Epidemiol & Biostat, Sch Publ Hlth, London W2 1PG, England.;UCL, Inst Hlth Informat, London NW1 2DA, England.;UCL, Inst Hlth Informat, Farr Inst Hlth Informat Res, London NW1 2DA, England.4 aut |
| 700 | 1 | a Mukamal, Kennethu Beth Israel Deaconess Med Ctr, Dept Med, Boston, MA 02215 USA.;Harvard Med Sch, Boston, MA 02215 USA.4 aut |
| 700 | 1 | a Nelson, Christopheru Univ Leicester, Glenfield Hosp, Dept Cardiovasc Sci, Leicester LE3 9QP, Leics, England.;Glenfield Hosp, Natl Inst Hlth Res, Leicester Cardiovasc Biomed Res Unit, Leicester LE3 9QP, Leics, England.4 aut |
| 700 | 1 | a Nettleton, Jenniferu Univ Texas Hlth Sci Ctr Houston, Div Epidemiol Human Genet & Environm Sci, Houston, TX 77225 USA.4 aut |
| 700 | 1 | a Partinen, Eemilu Univ Tartu, Fac Med, EE-50411 Tartu, Estonia.4 aut |
| 700 | 1 | a Rawal, Rajeshu Helmholtz Zentrum Munchen, Dept Mol Epidemiol, Inst Epidemiol 2, D-85764 Neuherberg, Germany.4 aut |
| 700 | 1 | a Robino, Antoniettau Ist Ricovero & Cura Carattere Sci IRCCS Burlo Gar, Inst Maternal & Child Hlth, I-34137 Trieste, Italy.4 aut |
| 700 | 1 | a Rose, Lyndau Brigham & Womens Hosp, Div Prevent Med, Boston, MA 02215 USA.4 aut |
| 700 | 1 | a Sala, Cinziau San Raffaele Res Inst, Div Genet & Cell Biol, I-20132 Milan, Italy.4 aut |
| 700 | 1 | a Satoh, Takashiu Osaka Univ, World Premier Int Immunol Frontier Res Ctr, Microbial Dis Res Inst, Lab Host Def, Osaka 5650871, Japan.4 aut |
| 700 | 1 | a Schmidt, Reinholdu Med Univ Graz, Clin Div Neurogeriatr, Dept Neurol, A-8036 Graz, Austria.4 aut |
| 700 | 1 | a Schrautz, Katharinau Univ Edinburgh, Usher Inst Populat Hlth Sci & Informat, Edinburgh EH8 9AG, Midlothian, Scotland.4 aut |
| 700 | 1 | a Scott, Robertu Univ Cambridge, Sch Clin Med, MRC, Epidemiol Unit, Cambridge CB2 0QQ, England.4 aut |
| 700 | 1 | a Smith, Albert Vernonu Iceland Heart Assoc, Res Inst, IS-201 Kopavogur, Iceland.4 aut |
| 700 | 1 | a Starr, John M.u Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Edinburgh EH8 9JZ, Midlothian, Scotland.;Univ Edinburgh, Alzheimer Scotland Res Ctr, Edinburgh EH8 9JZ, Midlothian, Scotland.4 aut |
| 700 | 1 | a Teumer, Alexanderu Univ Med Greifswald, Inst Community Med, D-17475 Greifswald, Germany.;Univ Med Greifswald, Interfac Inst Genet & Funct Genom, D-17475 Greifswald, Germany.4 aut |
| 700 | 1 | a Trompet, Stellau Leiden Univ, Med Ctr, Dept Cardiol, NL-2300 RC Leiden, Netherlands.;Leiden Univ, Med Ctr, Dept Gerontol & Geriatr, NL-2300 RC Leiden, Netherlands.4 aut |
| 700 | 1 | a Uitterlinden, Andre G.u Erasmus MC, Dept Internal Med, NL-3015 CN Rotterdam, Netherlands.;Erasmus MC, Dept Epidemiol, NL-3000 CA Rotterdam, Netherlands.4 aut |
| 700 | 1 | a Venturini, Cristinau Kings Coll London, Dept Twin Res & Genet Epidemiol, London SE1 7EH, England.4 aut |
| 700 | 1 | a Vergnaud, Anne-Claireu Imperial Coll London, Dept Epidemiol & Biostat, Sch Publ Hlth, London W2 1PG, England.4 aut |
| 700 | 1 | a Verweij, Nieku Univ Groningen, Univ Med Ctr Groningen, Dept Cardiol, NL-9700 RB Groningen, Netherlands.4 aut |
| 700 | 1 | a Vitart, Veroniqueu Univ Edinburgh, Western Gen Hosp, MRC, Human Genet Unit,Inst Genet & Mol Med, Edinburgh EH4 2XU, Midlothian, Scotland.4 aut |
| 700 | 1 | a Vuckovic, Draganau Univ Trieste, Dept Med Sci, I-34149 Trieste, Italy.4 aut |
| 700 | 1 | a Wedenoja, Juhou Univ Helsinki, Dept Publ Hlth, FIN-00014 Helsinki, Finland.4 aut |
| 700 | 1 | a Yengo, Loicu Univ Lille 2, European Genom Inst Diabet, Lille Pasteur Inst, CNRS,UMR 8199, F-59000 Lille, France.4 aut |
| 700 | 1 | a Yu, Bingu Univ Texas Hlth Sci Ctr Houston, Human Genet Ctr, Houston, TX 77225 USA.;Univ Texas Hlth Sci Ctr Houston, Div Epidemiol, Houston, TX 77225 USA.4 aut |
| 700 | 1 | a Zhang, Weihuau Imperial Coll London, Dept Epidemiol & Biostat, Sch Publ Hlth, London W2 1PG, England.;Ealing Gen Hosp, Dept Cardiol, Southall UB1 3HW, Middx, England.4 aut |
| 700 | 1 | a Zhao, Jing Huau Univ Cambridge, Sch Clin Med, MRC, Epidemiol Unit, Cambridge CB2 0QQ, England.4 aut |
| 700 | 1 | a Boomsma, Dorret I.u Vrije Univ Amsterdam, Dept Biol Psychol, NL-1081 BT Amsterdam, Netherlands.;EMGO Inst Hlth & Care Res, NL-1081 BT Amsterdam, Netherlands.4 aut |
| 700 | 1 | a Chambers, Johnu Imperial Coll London, Dept Epidemiol & Biostat, Sch Publ Hlth, London W2 1PG, England.;Ealing Gen Hosp, Dept Cardiol, Southall UB1 3HW, Middx, England.;Imperial Coll Healthcare Natl Hlth Serv Trust, London W12 0HS, England.4 aut |
| 700 | 1 | a Chasman, Daniel I.u Harvard Med Sch, Boston, MA 02215 USA.;Brigham & Womens Hosp, Div Prevent Med, Boston, MA 02215 USA.4 aut |
| 700 | 1 | a Daniela, Toniolou San Raffaele Res Inst, Div Genet & Cell Biol, I-20132 Milan, Italy.4 aut |
| 700 | 1 | a de Geus, Ecou Vrije Univ Amsterdam, Dept Biol Psychol, NL-1081 BT Amsterdam, Netherlands.;EMGO Inst Hlth & Care Res, NL-1081 BT Amsterdam, Netherlands.4 aut |
| 700 | 1 | a Deary, Ianu Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Edinburgh EH8 9JZ, Midlothian, Scotland.;Univ Edinburgh, Psychol, Edinburgh EH8 9JZ, Midlothian, Scotland.4 aut |
| 700 | 1 | a Eriksson, Johan G.u Natl Inst Hlth & Welf, Helsinki 00271, Finland.;Univ Helsinki, Dept Gen Practice & Primary Hlth Care, FIN-00014 Helsinki, Finland.;Univ Helsinki, Cent Hosp, Unit Gen Practice, FIN-00014 Helsinki, Finland.;Publ Hlth Res, Folkhalsan Res Ctr, Helsinki 00290, Finland.;Vasa Cent Hosp, Vaasa 65130, Finland.4 aut |
| 700 | 1 | a Esko, Tonuu Univ Tartu, Estonian Genome Ctr, EE-51010 Tartu, Estonia.4 aut |
| 700 | 1 | a Eulenburg, Volkeru Friedrich Alexander Univ Erlangen Nuremberg, Inst Biochem & Mol Med, D-91054 Erlangen, Germany.4 aut |
| 700 | 1 | a Franco, Oscar H.u Erasmus MC, Dept Epidemiol, NL-3000 CA Rotterdam, Netherlands.4 aut |
| 700 | 1 | a Froguel, Philippeu Univ Lille 2, European Genom Inst Diabet, Lille Pasteur Inst, CNRS,UMR 8199, F-59000 Lille, France.;Imperial Coll London, Dept Genom Common Dis, Sch Publ Hlth, London W12 0HR, England.4 aut |
| 700 | 1 | a Gieger, Christianu Helmholtz Zentrum Munchen, Dept Mol Epidemiol, Inst Epidemiol 2, D-85764 Neuherberg, Germany.4 aut |
| 700 | 1 | a Grabe, Hans J.u Univ Med Greifswald, Dept Psychiat & Psychotherapy, D-17475 Greifswald, Germany.4 aut |
| 700 | 1 | a Gudnason, Vilmunduru Iceland Heart Assoc, Res Inst, IS-201 Kopavogur, Iceland.;Univ Iceland, Fac Med, IS-101 Reykjavik, Iceland.4 aut |
| 700 | 1 | a Gyllensten, Ulf B.u Uppsala universitet,Science for Life Laboratory, SciLifeLab,Medicinsk genetik och genomik4 aut0 (Swepub:uu)ulfgyll |
| 700 | 1 | a Harris, Tamara B.u NIA, NIH, Bethesda, MD 20892 USA.4 aut |
| 700 | 1 | a Hartikainen, Anna-Liisau Oulu Univ Hosp, Dept Obstet & Gynecol, Oulu 90029, Finland.;Univ Oulu, MRC, Oulu 90014, Finland.;Oulu Univ Hosp, Unit Primary Care, Oulu 90220, Finland.4 aut |
| 700 | 1 | a Heath, Andrew C.u Washington Univ, Sch Med, Dept Psychiat, St Louis, MO 63110 USA.4 aut |
| 700 | 1 | a Hocking, Lynneu Univ Aberdeen, Inst Med Sci, Aberdeen AB25 2ZD, Scotland.4 aut |
| 700 | 1 | a Hofman, Albertu Erasmus MC, Dept Epidemiol, NL-3000 CA Rotterdam, Netherlands.4 aut |
| 700 | 1 | a Huth, Corneliau German Res Ctr Environm Hlth GmbH, Inst Epidemiol 2, Helmholtz Zentrum Munchen, D-85764 Neuherberg, Germany.4 aut |
| 700 | 1 | a Jarvelin, Marjo-Riittau Imperial Coll London, Dept Epidemiol & Biostat, Sch Publ Hlth, London W2 1PG, England.;Erasmus MC, Dept Internal Med, NL-3015 CN Rotterdam, Netherlands.;Oulu Univ Hosp, Unit Primary Care, Oulu 90220, Finland.;Univ Oulu, Fac Med, Ctr Life Course Epidemiol, FI-90014 Oulu, Finland.;Univ Oulu, Bioctr Oulu, FI-90014 Oulu, Finland.4 aut |
| 700 | 1 | a Jukema, J. Wouteru Leiden Univ, Med Ctr, Dept Cardiol, NL-2300 RC Leiden, Netherlands.4 aut |
| 700 | 1 | a Kaprio, Jaakkou Univ Helsinki, Inst Mol Med, Helsinki 00290, Finland.;Natl Inst Hlth & Welf, Helsinki 00271, Finland.;Univ Helsinki, Dept Publ Hlth, FIN-00014 Helsinki, Finland.4 aut |
| 700 | 1 | a Kooner, Jaspal S.u Ealing Gen Hosp, Dept Cardiol, Southall UB1 3HW, Middx, England.;Imperial Coll Healthcare Natl Hlth Serv Trust, London W12 0HS, England.;Imperial Coll London, Hammersmith Hosp, Natl Heart & Lung Inst, Fac Med,Cardiovasc Sci, London W12 0NN, England.4 aut |
| 700 | 1 | a Kutalik, Zoltanu Ctr Hosp Univ Vaudoise, Inst Social & Prevent Med, CH-1010 Lausanne, Switzerland.4 aut |
| 700 | 1 | a Lahti, Jariu Publ Hlth Res, Folkhalsan Res Ctr, Helsinki 00290, Finland.;Univ Helsinki, Coll Adv Studies, FIN-00014 Helsinki, Finland.;Univ Helsinki, Inst Behav Sci, FIN-00014 Helsinki, Finland.4 aut |
| 700 | 1 | a Langenberg, Claudiau Univ Cambridge, Sch Clin Med, MRC, Epidemiol Unit,Inst Metab Sci, Cambridge CB2 0QQ, England.4 aut |
| 700 | 1 | a Lehtimaki, Terhou Fimlab Labs, Dept Clin Chem, Tampere 33520, Finland.;Univ Tampere, Sch Med, Tampere 33520, Finland.4 aut |
| 700 | 1 | a Liu, Yongmeiu Wake Forest Sch Med, Wake Forest Sch Med, Dept Epidemiol & Prevent, Publ Hlth Sci, Winston Salem, NC 27157 USA.4 aut |
| 700 | 1 | a Madden, Pamela A. F.u Washington Univ, Sch Med, Dept Psychiat, St Louis, MO 63110 USA.4 aut |
| 700 | 1 | a Martin, Nicholasu Queensland Inst Med Res, Berghofer Med Res Inst, Genet Epidemiol, Brisbane, Qld 4029, Australia.4 aut |
| 700 | 1 | a Morrison, Alannau Univ Texas Hlth Sci Ctr Houston, Human Genet Ctr, Houston, TX 77225 USA.4 aut |
| 700 | 1 | a Penninx, Brendau Vrije Univ Amsterdam, Inst Hlth & Care Res EMGO, Inst Hlth & Care Res, Dept Psychiat,Univ Med Ctr,Geestelijke Gezondheid, NL-1081 HL Amsterdam, Netherlands.;Vrije Univ Amsterdam, Neurosci Campus Amsterdam, Univ Med Ctr, Geestelijke Gezondheids Zorg GGZ InGeest, NL-1081 HL Amsterdam, Netherlands.4 aut |
| 700 | 1 | a Pirastu, Nicolau Univ Edinburgh, Usher Inst Populat Hlth Sci & Informat, Edinburgh EH8 9AG, Midlothian, Scotland.;Univ Trieste, Dept Med Sci, I-34149 Trieste, Italy.4 aut |
| 700 | 1 | a Psaty, Bruceu Univ Washington, Dept Med, Cardiovasc Hlth Res Unit, Seattle, WA 98101 USA.;Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA.;Univ Washington, Dept Hlth Serv, Seattle, WA 98195 USA.;Grp Hlth Res Inst, Grp Hlth Cooperat, Seattle, WA 98101 USA.4 aut |
| 700 | 1 | a Raitakari, Olliu Univ Turku, Dept Clin Physiol & Nucl Med, Turku Univ Hosp, FIN-20520 Turku, Finland.;Univ Turku, Res Ctr Appl & Prevent Cardiovasc Med, FIN-20520 Turku, Finland.4 aut |
| 700 | 1 | a Ridker, Paulu Harvard Med Sch, Boston, MA 02215 USA.;Brigham & Womens Hosp, Div Prevent Med, Boston, MA 02215 USA.4 aut |
| 700 | 1 | a Rose, Richardu Indiana Univ, Dept Psychol & Brain Sci, Bloomington, IN 47405 USA.4 aut |
| 700 | 1 | a Rotter, Jerome I.u Univ Calif Los Angeles, Los Angeles Biomed Res Inst Harbor, Med Ctr, Inst Translat Genom & Populat Sci, Torrance, CA 90509 USA.4 aut |
| 700 | 1 | a Samani, Nilesh J.u Univ Leicester, Glenfield Hosp, Dept Cardiovasc Sci, Leicester LE3 9QP, Leics, England.;Glenfield Hosp, Natl Inst Hlth Res, Leicester Cardiovasc Biomed Res Unit, Leicester LE3 9QP, Leics, England.4 aut |
| 700 | 1 | a Schmidt, Helenau Med Univ Graz, Inst Mol Biol & Biochem, Ctr Mol Med, A-8010 Graz, Austria.4 aut |
| 700 | 1 | a Spector, Tim D.u Kings Coll London, Dept Twin Res & Genet Epidemiol, London SE1 7EH, England.4 aut |
| 700 | 1 | a Stott, Davidu Univ Glasgow, Inst Cardiovasc & Med Sci, Fac Med, Glasgow G31 2ER, Lanark, Scotland.4 aut |
| 700 | 1 | a Strachan, Davidu St Georges Univ London, Populat Hlth Res Inst, London SW17 0RE, England.4 aut |
| 700 | 1 | a Tzoulaki, Ioannau Imperial Coll London, Dept Epidemiol & Biostat, Sch Publ Hlth, London W2 1PG, England.;Imperial Coll London, MRC, Publ Hlth England Ctr Environm & Hlth, London W2 1PG, England.;Univ Ioannina, Dept Hyg & Epidemiol, Med Sch, GR-45110 Ioannina, Greece.4 aut |
| 700 | 1 | a van der Harst, Pimu Univ Groningen, Univ Med Ctr Groningen, Dept Cardiol, NL-9700 RB Groningen, Netherlands.;Univ Groningen, Univ Med Ctr Groningen, Dept Genet, NL-9700 RB Groningen, Netherlands.;Netherlands Heart Inst, Durrer Ctr Cardiogenet Res, Interuniv Cardiol Inst Netherlands, NL-3511 GC Utrecht, Netherlands.4 aut |
| 700 | 1 | a van Duijn, Cornelia M.u Erasmus MC, Genet Epidemiol Unit, Dept Epidemiol, NL-3000 CA Rotterdam, Netherlands.4 aut |
| 700 | 1 | a Marques-Vidal, Pedrou Univ Lausanne Hosp, Dept Med, Internal Med, CH-1011 Lausanne, Switzerland.4 aut |
| 700 | 1 | a Vollenweider, Peteru Univ Lausanne Hosp, Dept Med, Internal Med, CH-1011 Lausanne, Switzerland.4 aut |
| 700 | 1 | a Wareham, Nicholas J.u Univ Cambridge, Sch Clin Med, MRC, Epidemiol Unit, Cambridge CB2 0QQ, England.4 aut |
| 700 | 1 | a Whitfield, John B.u Queensland Inst Med Res, Berghofer Med Res Inst, Genet Epidemiol, Brisbane, Qld 4029, Australia.4 aut |
| 700 | 1 | a Wilson, Jamesu Univ Edinburgh, Usher Inst Populat Hlth Sci & Informat, Edinburgh EH8 9AG, Midlothian, Scotland.;Univ Edinburgh, Western Gen Hosp, MRC, Human Genet Unit,Inst Genet & Mol Med, Edinburgh EH4 2XU, Midlothian, Scotland.4 aut |
| 700 | 1 | a Wolffenbuttel, Bruceu Univ Groningen, Univ Med Ctr Groningen, Dept Endocrinol, NL-9700 RB Groningen, Netherlands.4 aut |
| 700 | 1 | a Bakalkin, Georgyu Uppsala universitet,Institutionen för farmaceutisk biovetenskap4 aut0 (Swepub:uu)gueba200 |
| 700 | 1 | a Evangelou, Evangelosu Imperial Coll London, Dept Epidemiol & Biostat, Sch Publ Hlth, London W2 1PG, England.;Univ Ioannina, Dept Hyg & Epidemiol, Med Sch, GR-45110 Ioannina, Greece.4 aut |
| 700 | 1 | a Liu, Yunu Minist Educ, Key Lab Metab & Mol Med, Shanghai 200032, Peoples R China.;Fudan Univ, Shanghai Med Coll, Dept Biochem & Mol Biol, Shanghai 200032, Peoples R China.4 aut |
| 700 | 1 | a Rice, Kenneth M.u Univ Washington, Dept Biostat, Seattle, WA 98195 USA.4 aut |
| 700 | 1 | a Desrivieres, Sylvaneu Kings Coll London, MRC, Inst Psychiat Psychol & Neurosci, Social Genet & Dev Psychiat Ctr, London SE5 8AF, England.4 aut |
| 700 | 1 | a Kliewer, Steven A.u Univ Texas Southwestern Med Ctr Dallas, Dept Pharmacol, Dallas, TX 75390 USA.;Univ Texas Southwestern Med Ctr Dallas, Dept Mol Biol, Dallas, TX 75390 USA.4 aut |
| 700 | 1 | a Mangelsdorf, David J.u Univ Texas Southwestern Med Ctr Dallas, Dept Pharmacol, Dallas, TX 75390 USA.;Univ Texas Southwestern Med Ctr Dallas, Howard Hughes Med Inst, Dallas, TX 75390 USA.4 aut |
| 700 | 1 | a Muller, Christian P.u Friedrich Alexander Univ Erlangen Nuremberg, Dept Psychiat & Psychotherapy, D-91054 Erlangen, Germany.4 aut |
| 700 | 1 | a Levy, Danielu Framingham Heart Dis Epidemiol Study, Framingham, MA 01702 USA.;NHLBI, Populat Sci Branch, Div Intramural Res, Bethesda, MD 20824 USA.4 aut |
| 700 | 1 | a Elliott, Paulu Imperial Coll London, Dept Epidemiol & Biostat, Sch Publ Hlth, London W2 1PG, England.;Imperial Coll London, MRC, Publ Hlth England Ctr Environm & Hlth, London W2 1PG, England.4 aut |
| 710 | 2 | a Kings Coll London, MRC, Inst Psychiat Psychol & Neurosci, Social Genet & Dev Psychiat Ctr, London SE5 8AF, England.b Framingham Heart Dis Epidemiol Study, Framingham, MA 01702 USA.;NHLBI, Populat Sci Branch, Div Intramural Res, Bethesda, MD 20824 USA.;Boston Univ, Sch Publ, Dept Biostat, Boston, MA 02118 USA.4 org |
| 773 | 0 | t Proceedings of the National Academy of Sciences of the United States of Americad : Proceedings of the National Academy of Sciencesg 113:50, s. 14372-14377q 113:50<14372-14377x 0027-8424x 1091-6490 |
| 856 | 4 | u https://www.pnas.org/content/pnas/113/50/14372.full.pdf |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-312625 |
| 856 | 4 8 | u https://doi.org/10.1073/pnas.1611243113 |
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