onr:"swepub:oai:DiVA.org:uu-376303"
Sökning: onr:"swepub:oai:DiVA.org:uu-376303" >
- 1 av
- Föregående post
- Till träfflistan
| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 15305naa a2201309 4500 | |
| 001 | oai:DiVA.org:uu-376303 | |
| 003 | SwePub | |
| 008 | 190204s2018 | |||||||||||000 ||eng| | |
| 009 | oai:prod.swepub.kib.ki.se:139544479 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3763032 URI |
| 024 | 7 | a https://doi.org/10.1038/s41467-018-06863-12 DOI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1395444792 URI |
| 040 | a (SwePub)uud (SwePub)ki | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Matejcic, Marcou Univ Southern Calif, Keck Sch Med, Dept Prevent Med, Norris Comprehens Canc Ctr, Los Angeles, CA 90033 USA,Amer Canc Soc, Epidemiol Res Program, 250 Williams St, Atlanta, GA 30303 USA,Fred Hutchinson Canc Res Ctr, SWOG Stat Ctr, Seattle, WA 98109 USA,Oslo Univ Hosp, Dept Med Genet, N-0424 Oslo, Norway4 aut |
| 245 | 1 0 | a Germline variation at 8q24 and prostate cancer risk in men of European ancestry |
| 264 | c 2018-11-05 | |
| 264 | 1 | b Springer Nature,c 2018 |
| 338 | a electronic2 rdacarrier | |
| 500 | a Correction in: NATURE COMMUNICATIONS, Volume: 10, Article Number: 382, DOI: 10.1038/s41467-019-08293-z | |
| 520 | a Chromosome 8q24 is a susceptibility locus for multiple cancers, including prostate cancer. Here we combine genetic data across the 8q24 susceptibility region from 71,535 prostate cancer cases and 52,935 controls of European ancestry to define the overall contribution of germline variation at 8q24 to prostate cancer risk. We identify 12 independent risk signals for prostate cancer (p < 4.28 x 10(-15)), including three risk variants that have yet to be reported. From a polygenic risk score (PRS) model, derived to assess the cumulative effect of risk variants at 8q24, men in the top 1% of the PRS have a 4-fold (95% CI = 3.62-4.40) greater risk compared to the population average. These 12 variants account for similar to 25% of what can be currently explained of the familial risk of prostate cancer by known genetic risk factors. These findings highlight the overwhelming contribution of germline variation at 8q24 on prostate cancer risk which has implications for population risk stratification. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Urologi och njurmedicin0 (SwePub)302142 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Urology and Nephrology0 (SwePub)302142 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
| 700 | 1 | a Saunders, Edward J.u Inst Canc Res, London SW7 3RP, England4 aut |
| 700 | 1 | a Dadaev, Tokhiru Inst Canc Res, London SW7 3RP, England4 aut |
| 700 | 1 | a Brook, Mark N.u Inst Canc Res, London SW7 3RP, England4 aut |
| 700 | 1 | a Wang, Kanu Univ Southern Calif, Keck Sch Med, Dept Prevent Med, Norris Comprehens Canc Ctr, Los Angeles, CA 90033 USA4 aut |
| 700 | 1 | a Sheng, Xinu Univ Southern Calif, Keck Sch Med, Dept Prevent Med, Norris Comprehens Canc Ctr, Los Angeles, CA 90033 USA4 aut |
| 700 | 1 | a Al Olama, Ali Aminu Univ Cambridge, Ctr Canc Genet Epidemiol, Dept Publ Hlth & Primary Care, Strangeways Res Lab, Cambridge CB1 8RN, England.;Univ Cambridge, Dept Clin Neurosci, Cambridge CB2 0QQ, England4 aut |
| 700 | 1 | a Schumacher, Fredrick R.u Case Western Reserve Univ, Dept Populat & Quantitat Hlth Sci, Cleveland, OH 44106 USA.;Univ Hosp, Seidman Canc Ctr, Cleveland, OH 44106 USA4 aut |
| 700 | 1 | a Ingles, Sue A.u Univ Southern Calif, Keck Sch Med, Dept Prevent Med, Norris Comprehens Canc Ctr, Los Angeles, CA 90033 USA4 aut |
| 700 | 1 | a Govindasami, Koveelau Inst Canc Res, London SW7 3RP, England4 aut |
| 700 | 1 | a Benlloch, Sarau Inst Canc Res, London SW7 3RP, England.;Univ Cambridge, Ctr Canc Genet Epidemiol, Dept Publ Hlth & Primary Care, Strangeways Res Lab, Cambridge CB1 8RN, England4 aut |
| 700 | 1 | a Berndt, Sonja, Iu NCI, Div Canc Epidemiol & Genet, NIH, Bethesda, MD 20892 USA4 aut |
| 700 | 1 | a Albanes, Demetriusu NCI, Div Canc Epidemiol & Genet, NIH, Bethesda, MD 20892 USA4 aut |
| 700 | 1 | a Koutros, Stellau NCI, Div Canc Epidemiol & Genet, NIH, Bethesda, MD 20892 USA4 aut |
| 700 | 1 | a Muir, Kennethu Univ Manchester, Inst Populat Hlth, Manchester M13 9PL, Lancs, England.;Univ Warwick, Warwick Med Sch, Coventry CV4 7AL, W Midlands, England4 aut |
| 700 | 1 | a Stevens, Victoria L.u Amer Canc Soc, Epidemiol Res Program, 250 Williams St, Atlanta, GA 30303 USA4 aut |
| 700 | 1 | a Gapstur, Susan M.u Amer Canc Soc, Epidemiol Res Program, 250 Williams St, Atlanta, GA 30303 USA4 aut |
| 700 | 1 | a Tangen, Catherine M.u Fred Hutchinson Canc Res Ctr, SWOG Stat Ctr, Seattle, WA 98109 USA4 aut |
| 700 | 1 | a Batra, Jyotsnau Queensland Univ Technol, Australian Prostate Canc Res Ctr Qld, Inst Hlth & Biomed Innovat, Brisbane, Qld 4059, Australia.;Queensland Univ Technol, Sch Biomed Sci, Brisbane, Qld 4059, Australia.;Translat Res Inst, Brisbane, Qld 4102, Australia4 aut |
| 700 | 1 | a Clements, Judithu Queensland Univ Technol, Australian Prostate Canc Res Ctr Qld, Inst Hlth & Biomed Innovat, Brisbane, Qld 4059, Australia.;Queensland Univ Technol, Sch Biomed Sci, Brisbane, Qld 4059, Australia.;Translat Res Inst, Brisbane, Qld 4102, Australia4 aut |
| 700 | 1 | a Gronberg, Henriku Karolinska Institutet,Karolinska Inst, Dept Med Epidemiol & Biostat, SE-17177 Stockholm, Sweden4 aut |
| 700 | 1 | a Pashayan, Norau Univ Cambridge, Ctr Canc Genet Epidemiol, Dept Oncol, Strangeways Res Lab, Cambridge CB1 8RN, England.;UCL, Dept Appl Hlth Res, London WC1E 7HB, England4 aut |
| 700 | 1 | a Schleutker, Johannau Univ Turku, Inst Biomed, Dept Med Biochem & Genet, FI-20014 Turku, Finland.;Turku Univ Hosp, Dept Med Genet, Tyks Microbiol & Genet, Turku 20521, Finland.;Univ Tampere, BioMediTech, Tampere 33520, Finland4 aut |
| 700 | 1 | a Wolk, Alicjau Karolinska Institutet,Uppsala universitet,Institutionen för kirurgiska vetenskaper,Karolinska Inst, Inst Environm Med, Div Nutr Epidemiol, SE-17177 Stockholm, Sweden4 aut0 (Swepub:uu)alwol516 |
| 700 | 1 | a West, Catharineu Univ Manchester, Christie Hosp NHS Fdn Trust, Manchester Acad Hlth Sci Ctr,Div Canc Sci, Manchester NIHR Biomed Res Ctr,Radiotherapy Relat, Manchester M13 9PL, Lancs, England4 aut |
| 700 | 1 | a Mucci, Loreleiu Harvard Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA4 aut |
| 700 | 1 | a Kraft, Peteru Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Program Genet Epidemiol & Stat Genet, Boston, MA 02115 USA4 aut |
| 700 | 1 | a Cancel-Tassin, Geraldineu UPMC Univ Paris 06, Tenon Hosp, GRC ONCOTYPE URO 5, F-75020 Paris, France.;Tenon Hosp, CeRePP, F-75020 Paris, France4 aut |
| 700 | 1 | a Sorensen, Karina D.u Aarhus Univ Hosp, Dept Mol Med, DK-8200 Aarhus N, Denmark.;Aarhus Univ, Dept Clin Med, DK-8200 Aarhus N, Denmark4 aut |
| 700 | 1 | a Maehle, Loviseu Oslo Univ Hosp, Dept Med Genet, N-0424 Oslo, Norway4 aut |
| 700 | 1 | a Grindedal, Eli M.u Oslo Univ Hosp, Dept Med Genet, N-0424 Oslo, Norway4 aut |
| 700 | 1 | a Strom, Sara S.u Univ Texas MD Anderson Canc Ctr, Dept Epidemiol, Houston, TX 77030 USA,Brigham & Womens Hosp, Div Urol Surg, Boston, MA 02115 USA4 aut |
| 700 | 1 | a Neal, David E.u Univ Cambridge, Addenbrookes Hosp, Dept Oncol, Cambridge CB2 0QQ, England.;Li Ka Shing Ctr, Canc Res UK Cambridge Res Inst, Cambridge CB2 0RE, England4 aut |
| 700 | 1 | a Hamdy, Freddie C.u Univ Oxford, Nuffield Dept Surg Sci, Oxford OX1 2JD, England,Pomeranian Med Univ, Int Hereditary Canc Ctr, Dept Genet & Pathol, PL-70115 Szczecin, Poland4 aut |
| 700 | 1 | a Donovan, Jenny L.u Univ Bristol, Sch Social & Community Med, Canynge Hall,39 Whatley Rd, Bristol BS8 2PS, Avon, England4 aut |
| 700 | 1 | a Travis, Ruth C.u Univ Oxford, Nuffield Dept Populat Hlth, Canc Epidemiol, Oxford OX3 7LF, England4 aut |
| 700 | 1 | a Hamilton, Robert J.u Princess Margaret Canc Ctr, Dept Surg Oncol, Toronto, ON M5G 2M9, Canada4 aut |
| 700 | 1 | a Rosenstein, Barryu Icahn Sch Med Mt Sinai, Dept Radiat Oncol, New York, NY 10029 USA.;Icahn Sch Med Mt Sinai, Dept Genet & Genom Sci, New York, NY 10029 USA4 aut |
| 700 | 1 | a Lu, Yong-Jieu Queen Mary Univ London, Ctr Mol Oncol, John Vane Sci Ctr, Barts Canc Inst, London EC1M 6BQ, England4 aut |
| 700 | 1 | a Giles, Graham G.u Canc Council Victoria, Canc Epidemiol & Intelligence Div, Melbourne, Vic 3004, Australia.;Univ Melbourne, Ctr Epidemiol & Biostat, Melbourne Sch Populat & Global Hlth, Melbourne, Vic 3010, Australia,Univ Copenhagen, Fac Hlth & Med Sci, DK-2200 Copenhagen, Denmark.;Copenhagen Univ Hosp, Herlev & Gentofte Hosp, Dept Clin Biochem, DK-2200 Copenhagen, Denmark,Complejo Hosp Univ Santiago, Inst Invest Sanitaria Santiago de Compostela IDIS, SERGAS, Genom Med Grp,Galician Fdn Genom Med,Serv Galego, Santiago De Compostela 15706, Spain.;Univ Calif San Diego, Moores Canc Ctr, La Jolla, CA 92037 USA4 aut |
| 700 | 1 | a Kibel, Adam S.u Brigham & Womens Hosp, Div Urol Surg, Boston, MA 02115 USA4 aut |
| 700 | 1 | a Vega, Anau Fdn Publ Galega Med Xenom SERGAS, CIBERER, IDIS, Grp Med Xenom, Santiago De Compostela 15706, Spain4 aut |
| 700 | 1 | a Bensen, Jeanette T.u Univ N Carolina, Gillings Sch Global Publ Hlth, Dept Epidemiol, Columbia, SC 29208 USA4 aut |
| 700 | 1 | a Kogevinas, Manolisu Barcelona Inst Global Hlth ISGlobal, Ctr Res Environm Epidemiol CREAL, Barcelona 08003, Spain.;CIBER Epidemiol & Salud Publ CIBERESP, Madrid 28029, Spain.;Hosp del Mar, IMIM, Res Inst, Barcelona 08003, Spain.;UPF, Barcelona 08002, Spain4 aut |
| 700 | 1 | a Penney, Kathryn L.u Harvard Med Sch, Dept Med, Channing Div Network Med, Brigham & Womens Hosp, Boston, MA 02184 USA4 aut |
| 700 | 1 | a Park, Jong Y.u H Lee Moffitt Canc Ctr & Res Inst, Dept Canc Epidemiol, Tampa, FL 33612 USA4 aut |
| 700 | 1 | a Stanford, Janet L.u Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, Seattle, WA 98109 USA.;Univ Washington, Sch Publ Hlth, Dept Epidemiol, Seattle, WA 98195 USA4 aut |
| 700 | 1 | a Cybulski, Cezaryu Pomeranian Med Univ, Int Hereditary Canc Ctr, Dept Genet & Pathol, PL-70115 Szczecin, Poland4 aut |
| 700 | 1 | a Nordestgaard, Borge G.u Univ Copenhagen, Fac Hlth & Med Sci, DK-2200 Copenhagen, Denmark.;Copenhagen Univ Hosp, Herlev & Gentofte Hosp, Dept Clin Biochem, DK-2200 Copenhagen, Denmark4 aut |
| 700 | 1 | a Brenner, Hermannu German Canc Res Ctr, Div Clin Epidemiol & Aging Res, D-69120 Heidelberg, Germany.;German Canc Res Ctr, German Canc Consortium DKTK, D-69120 Heidelberg, Germany.;German Canc Res Ctr, Div Prevent Oncol, D-69120 Heidelberg, Germany.;Natl Ctr Tumor Dis NCT, D-69120 Heidelberg, Germany4 aut |
| 700 | 1 | a Maier, Christianeu Univ Hosp Ulm, Inst Human Genet, D-89075 Ulm, Germany4 aut |
| 700 | 1 | a Kim, Jeriu Univ Texas MD Anderson Canc Ctr, Dept Genitourinary Med Oncol, Houston, TX 77030 USA4 aut |
| 700 | 1 | a Teixeira, Manuel R.u Portuguese Oncol Inst Porto, Dept Genet, P-4200072 Porto, Portugal.;Univ Porto, Biomed Sci Inst ICBAS, P-4050313 Porto, Portugal4 aut |
| 700 | 1 | a Neuhausen, Susan L.u Beckman Res Inst City Hope, Dept Populat Sci, Duarte, CA 91010 USA4 aut |
| 700 | 1 | a De Ruyck, Kimu Univ Ghent, Fac Med & Hlth Sci, Basic Med Sci, B-9000 Ghent, Belgium4 aut |
| 700 | 1 | a Razack, Azadu Univ Malaya, Fac Med, Dept Surg, Kuala Lumpur 50603, Malaysia4 aut |
| 700 | 1 | a Newcomb, Lisa F.u Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, Seattle, WA 98109 USA.;Univ Washington, Dept Urol, Seattle, WA 98195 USA4 aut |
| 700 | 1 | a Lessel, Davoru Univ Med Ctr Hamburg Eppendorf, Inst Human Genet, D-20246 Hamburg, Germany4 aut |
| 700 | 1 | a Kaneva, Radkau Med Univ Sofia, Mol Med Ctr, Dept Med Chem & Biochem, Sofia 1431, Bulgaria4 aut |
| 700 | 1 | a Usmani, Nawaidu Univ Alberta, Cross Canc Inst, Dept Oncol, Edmonton, AB T6G 1Z2, Canada.;Univ Alberta, Cross Canc Inst, Div Radiat Oncol, Edmonton, AB T6G 1Z2, Canada4 aut |
| 700 | 1 | a Claessens, Franku Katholieke Univ Leuven, Mol Endocrinol Lab, Dept Cellular & Mol Med, BE-3000 Leuven, Belgium4 aut |
| 700 | 1 | a Townsend, Paul A.u Univ Manchester, Manchester Acad Hlth Sci Ctr, Fac Biol Med & Hlth,Hlth Innovat Manchester, Manchester Canc Res Ctr,NIHR Manchester Biomed Re, Manchester M13 9WL, Lancs, England4 aut |
| 700 | 1 | a Dominguez, Manuela G.u Complejo Hosp Univ Santiago, Inst Invest Sanitaria Santiago de Compostela IDIS, SERGAS, Genom Med Grp,Galician Fdn Genom Med,Serv Galego, Santiago De Compostela 15706, Spain.;Univ Calif San Diego, Moores Canc Ctr, La Jolla, CA 92037 USA4 aut |
| 700 | 1 | a Roobol, Monique J.u Erasmus Univ, Dept Urol, Med Ctr, NL-3015 CE Rotterdam, Netherlands4 aut |
| 700 | 1 | a Menegaux, Florenceu Univ Paris Sud, Univ Paris Saclay, Ctr Res Epidemiol & Populat Hlth CESP, INSERM,Canc & Environm Grp, F-94807 Villejuif, France4 aut |
| 700 | 1 | a Khaw, Kay-Teeu Univ Cambridge, Clin Gerontol Unit, Cambridge CB2 2QQ, England4 aut |
| 700 | 1 | a Cannon-Albright, Lisa A.u Univ Utah, Dept Med, Div Genet Epidemiol, Sch Med, Salt Lake City, UT 84112 USA.;George E Wahlen Dept Vet Affairs Med Ctr, Salt Lake City, UT 84148 USA4 aut |
| 700 | 1 | a Pandha, Hardevu Univ Surrey, Guildford GU2 7XH, Surrey, England4 aut |
| 700 | 1 | a Thibodeau, Stephen N.u Mayo Clin, Dept Lab Med & Pathol, Rochester, MN 55905 USA4 aut |
| 700 | 1 | a Schaid, Daniel J.u Mayo Clin, Div Biomed Stat & Informat, Rochester, MN 55905 USA4 aut |
| 700 | 1 | a Wiklund, Fredriku Karolinska Institutet,Karolinska Inst, Dept Med Epidemiol & Biostat, SE-17177 Stockholm, Sweden4 aut |
| 700 | 1 | a Chanock, Stephen J.u NCI, Div Canc Epidemiol & Genet, NIH, Bethesda, MD 20892 USA4 aut |
| 700 | 1 | a Easton, Douglas F.u Univ Cambridge, Ctr Canc Genet Epidemiol, Dept Publ Hlth & Primary Care, Strangeways Res Lab, Cambridge CB1 8RN, England.;Univ Cambridge, Ctr Canc Genet Epidemiol, Dept Oncol, Strangeways Res Lab, Cambridge CB1 8RN, England4 aut |
| 700 | 1 | a Eeles, Rosalind A.u Inst Canc Res, London SW7 3RP, England.;Royal Marsden NHS Fdn Trust, London SW3 6JJ, England4 aut |
| 700 | 1 | a Kote-Jarai, Zsofiau Inst Canc Res, London SW7 3RP, England4 aut |
| 700 | 1 | a Conti, David, Vu Univ Southern Calif, Keck Sch Med, Dept Prevent Med, Norris Comprehens Canc Ctr, Los Angeles, CA 90033 USA4 aut |
| 700 | 1 | a Haiman, Christopher A.u Univ Southern Calif, Keck Sch Med, Dept Prevent Med, Norris Comprehens Canc Ctr, Los Angeles, CA 90033 USA4 aut |
| 710 | 2 | a Univ Southern Calif, Keck Sch Med, Dept Prevent Med, Norris Comprehens Canc Ctr, Los Angeles, CA 90033 USAb Amer Canc Soc, Epidemiol Res Program, 250 Williams St, Atlanta, GA 30303 USA4 org |
| 773 | 0 | t Nature Communicationsd : Springer Natureg 9q 9x 2041-1723 |
| 856 | 4 | u https://doi.org/10.1038/s41467-018-06863-1y Fulltext |
| 856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:1285377/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
| 856 | 4 | u https://www.nature.com/articles/s41467-018-06863-1.pdf |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-376303 |
| 856 | 4 8 | u https://doi.org/10.1038/s41467-018-06863-1 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:139544479 |
Till lärosätets databas
- 1 av
- Föregående post
- Till träfflistan
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - Nationella bibliotekssystem
- LIBRIS.kb.se
