Sökning: L773:0306 0012 > Multivalent glycoco...
Fältnamn | Indikatorer | Metadata |
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000 | 06592naa a2200709 4500 | |
001 | oai:DiVA.org:kth-305700 | |
003 | SwePub | |
008 | 211206s2013 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-3057002 URI |
024 | 7 | a https://doi.org/10.1039/c2cs35408j2 DOI |
040 | a (SwePub)kth | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a for2 swepub-publicationtype |
100 | 1 | a Bernardi, Annau Univ Milan, Dipartimento Chim Organ & Ind, I-20133 Milan, Italy.;Univ Milan, Ctr Eccellenza CISI, I-20133 Milan, Italy.4 aut |
245 | 1 0 | a Multivalent glycoconjugates as anti-pathogenic agents |
264 | c 2013 | |
264 | 1 | b Royal Society of Chemistry (RSC),c 2013 |
338 | a print2 rdacarrier | |
500 | a QC 20211206 | |
520 | a Multivalency plays a major role in biological processes and particularly in the relationship between pathogenic microorganisms and their host that involves protein-glycan recognition. These interactions occur during the first steps of infection, for specific recognition between host and bacteria, but also at different stages of the immune response. The search for high-affinity ligands for studying such interactions involves the combination of carbohydrate head groups with different scaffolds and linkers generating multivalent glycocompounds with controlled spatial and topology parameters. By interfering with pathogen adhesion, such glycocompounds including glycopolymers, glycoclusters, glycodendrimers and glyconanoparticles have the potential to improve or replace antibiotic treatments that are now subverted by resistance. Multivalent glycoconjugates have also been used for stimulating the innate and adaptive immune systems, for example with carbohydrate-based vaccines. Bacteria present on their surfaces natural multivalent glycoconjugates such as lipopolysaccharides and S-layers that can also be exploited or targeted in anti-infectious strategies. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Mikrobiologi inom det medicinska området0 (SwePub)301092 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Microbiology in the medical area0 (SwePub)301092 hsv//eng |
700 | 1 | a Jimenez-Barbero, Jesusu CSIC, Ctr Invest Biol, Madrid 28040, Spain.4 aut |
700 | 1 | a Casnati, Alessandrou Univ Parma, Dipartimento Chim, I-43100 Parma, Italy.4 aut |
700 | 1 | a De Castro, Cristinau Univ Naples Federico II, Dept Chem Sci, I-80126 Naples, Italy.4 aut |
700 | 1 | a Darbre, Tamisu Univ Bern, Dept Chem & Biochem, CH-3012 Bern, Switzerland.4 aut |
700 | 1 | a Fieschi, Francku Inst Biol Struct, F-38027 Grenoble 1, France.4 aut |
700 | 1 | a Finne, Jukkau Univ Helsinki, Dept Biosci, FI-00014 Helsinki, Finland.4 aut |
700 | 1 | a Funken, Horstu Univ Dusseldorf, Forschungszentrum Julich, Inst Mol Enzyme Technol, D-42425 Julich, Germany.4 aut |
700 | 1 | a Jaeger, Karl-Erichu Univ Dusseldorf, Forschungszentrum Julich, Inst Mol Enzyme Technol, D-42425 Julich, Germany.4 aut |
700 | 1 | a Lahmann, Martinau Bangor Univ, Sch Chem, Bangor LL57 2UW, Gwynedd, Wales.4 aut0 (Swepub:kth)u190mcjj |
700 | 1 | a Lindhorst, Thisbe K.u Univ Kiel, Otto Diels Inst Organ Chem, D-24098 Kiel, Germany.4 aut |
700 | 1 | a Marradi, Marcou CIC BiomaGUNE, Lab GlycoNanotechnol, San Sebastian 20009, Spain.;CIBER BBN, San Sebastian 20009, Spain.4 aut |
700 | 1 | a Messner, Paulu Univ Nat Resources & Life Sci, NanoGlycobiol Unit, Dept NanoBiotechnol, A-1190 Vienna, Austria.4 aut |
700 | 1 | a Molinaro, Antoniou Univ Naples Federico II, Dept Chem Sci, I-80126 Naples, Italy.4 aut |
700 | 1 | a Murphy, Paul V.u Natl Univ Ireland, Sch Chem, Galway, Ireland.4 aut |
700 | 1 | a Nativi, Cristinau Univ Florence, Dipartimento Chim, I-50019 Sesto Fiorentino, Italy.4 aut |
700 | 1 | a Oscarson, Stefanu Univ Coll Dublin, UCD Sch Chem & Chem Biol, Ctr Synth & Chem Biol, Dublin 4, Ireland.4 aut |
700 | 1 | a Penades, Soledadu CIC BiomaGUNE, Lab GlycoNanotechnol, San Sebastian 20009, Spain.;CIBER BBN, San Sebastian 20009, Spain.4 aut |
700 | 1 | a Peri, Francescou Univ Milano Bicocca, I-20126 Milan, Italy.4 aut |
700 | 1 | a Pieters, Roland J.u Univ Utrecht, Utrecht Inst Pharmaceut Sci, Dept Med Chem & Chem Biol, NL-3508 TB Utrecht, Netherlands.4 aut |
700 | 1 | a Renaudet, Olivieru Univ Grenoble 1, UMR CNRS 5250, Dept Chim Mol, F-38041 Grenoble, France.;Univ Grenoble 1, ICMG FR 2607, F-38041 Grenoble, France.4 aut |
700 | 1 | a Reymond, Jean-Louisu Univ Bern, Dept Chem & Biochem, CH-3012 Bern, Switzerland.4 aut |
700 | 1 | a Richichi, Barbarau Univ Florence, Dipartimento Chim, I-50019 Sesto Fiorentino, Italy.4 aut |
700 | 1 | a Rojo, Javieru Univ Seville, CSIC, Inst Invest Quim, Glycosyst Lab, Seville 41092, Spain.4 aut |
700 | 1 | a Sansone, Francescou Univ Parma, Dipartimento Chim, I-43100 Parma, Italy.4 aut |
700 | 1 | a Schaeffer, Christinau Univ Nat Resources & Life Sci, NanoGlycobiol Unit, Dept NanoBiotechnol, A-1190 Vienna, Austria.4 aut |
700 | 1 | a Turnbull, W. Bruceu Univ Leeds, Sch Chem, Leeds LS2 9JT, W Yorkshire, England.;Univ Leeds, Astbury Ctr Struct Mol Biol, Leeds LS2 9JT, W Yorkshire, England.4 aut |
700 | 1 | a Velasco-Torrijos, Trinidadu Natl Univ Ireland, Dept Chem, Maynooth, Kildare, Ireland.4 aut |
700 | 1 | a Vidal, Sebastienu Univ Lyon 1, CNRS, Inst Chim & Biochim Mol & Supramol UMR 5246, F-69622 Villeurbanne, France.;Univ Namur FUNDP, Dept Chim, Chim Bioorgan Lab, B-5000 Namur, Belgium.4 aut |
700 | 1 | a Vincent, Stephane4 aut |
700 | 1 | a Wennekes, Tomu Wageningen Univ, Organ Chem Lab, NL-6703 HB Wageningen, Netherlands.4 aut |
700 | 1 | a Zuilhof, Hanu Wageningen Univ, Organ Chem Lab, NL-6703 HB Wageningen, Netherlands.;King Abdulaziz Univ, Dept Chem & Mat Engn, Jeddah 21413, Saudi Arabia.4 aut |
700 | 1 | a Imberty, Anneu Univ Grenoble, Ctr Rech Macromol Vegetales CERMAV CNRS, F-38041 Grenoble, France.4 aut |
710 | 2 | a Univ Milan, Dipartimento Chim Organ & Ind, I-20133 Milan, Italy.;Univ Milan, Ctr Eccellenza CISI, I-20133 Milan, Italy.b CSIC, Ctr Invest Biol, Madrid 28040, Spain.4 org |
773 | 0 | t Chemical Society Reviewsd : Royal Society of Chemistry (RSC)g 42:11, s. 4709-4727q 42:11<4709-4727x 0306-0012x 1460-4744 |
856 | 4 | u https://doi.org/10.1039/c2cs35408jy Fulltext |
856 | 4 | u https://pubs.rsc.org/en/content/articlepdf/2013/cs/c2cs35408j |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-305700 |
856 | 4 8 | u https://doi.org/10.1039/c2cs35408j |
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