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Search: WFRF:(Barthel P. D.) > Amyloid-PET and 18-...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00007015naa a2200877 4500
001oai:gup.ub.gu.se/298296
003SwePub
008240528s2020 | |||||||||||000 ||eng|
009oai:lup.lub.lu.se:a21078b1-2879-44e6-9603-c25a12e5ff86
009oai:prod.swepub.kib.ki.se:145070034
024a https://gup.ub.gu.se/publication/2982962 URI
024a https://doi.org/10.1016/S1474-4422(20)30314-82 DOI
024a https://lup.lub.lu.se/record/a21078b1-2879-44e6-9603-c25a12e5ff862 URI
024a http://kipublications.ki.se/Default.aspx?queryparsed=id:1450700342 URI
040 a (SwePub)gud (SwePub)lud (SwePub)ki
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a for2 swepub-publicationtype
100a Chetelat, G.u University of Caen Normandy4 aut
2451 0a Amyloid-PET and 18-F-FDG-PET in the diagnostic investigation of Alzheimer's disease and other dementias
264 1c 2020
520 a Various biomarkers are available to support the diagnosis of neurodegenerative diseases in clinical and research settings. Among the molecular imaging biomarkers, amyloid-PET, which assesses brain amyloid deposition, and F-18-fluorodeoxyglucose (F-18-FDG) PET, which assesses glucose metabolism, provide valuable and complementary information. However, uncertainty remains regarding the optimal timepoint, combination, and an order in which these PET biomarkers should be used in diagnostic evaluations because conclusive evidence is missing. Following an expert panel discussion, we reached an agreement on the specific use of the individual biomarkers, based on available evidence and clinical expertise. We propose a diagnostic algorithm with optimal timepoints for these PET biomarkers, also taking into account evidence from other biomarkers, for early and differential diagnosis of neurodegenerative diseases that can lead to dementia. We propose three main diagnostic pathways with distinct biomarker sequences, in which amyloid-PET and F-18-FDG-PET are placed at different positions in the order of diagnostic evaluations, depending on clinical presentation. We hope that this algorithm can support diagnostic decision making in specialist clinical settings with access to these biomarkers and might stimulate further research towards optimal diagnostic strategies.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Neurovetenskaper0 (SwePub)301052 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Neurosciences0 (SwePub)301052 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Neurologi0 (SwePub)302072 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Neurology0 (SwePub)302072 hsv//eng
653 a mild cognitive impairment
653 a progressive supranuclear palsy
653 a cerebrospinal-fluid biomarkers
653 a positron-emission-tomography
653 a differential-diagnosis
653 a clinical-diagnosis
653 a national institute
653 a csf
653 a biomarkers
653 a fdg-pet
653 a a-beta
653 a Neurosciences & Neurology
700a Arbizu, J.u University of Navarra,University Clinic of Navarra4 aut
700a Barthel, H.u University Hospital Leipzig4 aut
700a Garibotto, V.u University of Geneva,Geneva University Hospital4 aut
700a Law, I.u Copenhagen University Hospital4 aut
700a Morbelli, S.u Ospedale Policlinico San Martino,University of California, Berkeley4 aut
700a van de Giessen, E.u University of Amsterdam,Academic Medical Center of University of Amsterdam (AMC)4 aut
700a Agosta, F.u Vita-Salute San Raffaele University,San Raffaele Scientific Institute4 aut
700a Barkhof, F.u University College London,Academic Medical Center of University of Amsterdam (AMC),Vrije Universiteit Amsterdam,Geneva University Hospital,University of Geneva4 aut
700a Brooks, D. J.u University of Newcastle upon Tyne,Aarhus University Hospital4 aut
700a Carrillo, M. C.u Alzheimer's Association: Alzheimer's Disease and Dementia4 aut
700a Dubois, B.u Paris-Sorbonne University,Pitié-Salpêtrière University Hospital4 aut
700a Fjell, A. M.u Oslo university hospital,University of Oslo4 aut
700a Frisoni, G. B.4 aut
700a Hansson, Oskaru Lund University,Lunds universitet,Klinisk minnesforskning,Forskargrupper vid Lunds universitet,Clinical Memory Research,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)mphy-ohn
700a Herholz, K.u University of Manchester4 aut
700a Hutton, B. F.u University College London4 aut
700a Jack, C. R.u Mayo Clinic Minnesota4 aut
700a Lammertsma, A. A.u Amsterdam UMC - Vrije Universiteit Amsterdam,Vrije Universiteit Amsterdam4 aut
700a Landau, S. M.u University of Utah4 aut
700a Minoshima, S.4 aut
700a Nobili, F.u University of Genoa,Ospedale Policlinico San Martino4 aut
700a Nordberg, A.u Karolinska Institutet,Karolinska Institute4 aut
700a Ossenkoppele, Riku Lund University,Lunds universitet,Klinisk minnesforskning,Forskargrupper vid Lunds universitet,Clinical Memory Research,Lund University Research Groups,Vrije Universiteit Amsterdam,Amsterdam UMC - Vrije Universiteit Amsterdam4 aut0 (Swepub:lu)ri1513os
700a Oyen, W. J. G.u Rijnstate Hospital,Radboud University Medical Center,Humanitas University,Humanitas Research Hospital4 aut
700a Perani, D.u San Raffaele Hospital,Vita-Salute San Raffaele University4 aut
700a Rabinovici, G. D.u University of California, San Francisco4 aut
700a Scheltens, P.u Vrije Universiteit Amsterdam,Amsterdam UMC - Vrije Universiteit Amsterdam4 aut
700a Villemagne, V. L.u University of Melbourne,Edith Cowan University,Austin Health4 aut
700a Zetterberg, Henrik,d 1973u University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry,Sahlgrenska University Hospital,University College London4 aut0 (Swepub:lu)med-hiz
700a Drzezga, A.u University of Cologne,German Center for Neurodegenerative Diseases (DZNE), Bonn,Jülich Research Centre4 aut
710a University of Caen Normandyb University of Navarra4 org
773t Lancet Neurologyg 19:11, s. 951-962q 19:11<951-962x 1474-4422x 1474-4465
856u http://dx.doi.org/10.1016/S1474-4422(20)30314-8y FULLTEXT
8564 8u https://gup.ub.gu.se/publication/298296
8564 8u https://doi.org/10.1016/S1474-4422(20)30314-8
8564 8u https://lup.lub.lu.se/record/a21078b1-2879-44e6-9603-c25a12e5ff86
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:145070034

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