Search: WFRF:(Barthel P. D.) > Amyloid-PET and 18-...
Fältnamn | Indikatorer | Metadata |
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000 | 07015naa a2200877 4500 | |
001 | oai:gup.ub.gu.se/298296 | |
003 | SwePub | |
008 | 240528s2020 | |||||||||||000 ||eng| | |
009 | oai:lup.lub.lu.se:a21078b1-2879-44e6-9603-c25a12e5ff86 | |
009 | oai:prod.swepub.kib.ki.se:145070034 | |
024 | 7 | a https://gup.ub.gu.se/publication/2982962 URI |
024 | 7 | a https://doi.org/10.1016/S1474-4422(20)30314-82 DOI |
024 | 7 | a https://lup.lub.lu.se/record/a21078b1-2879-44e6-9603-c25a12e5ff862 URI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1450700342 URI |
040 | a (SwePub)gud (SwePub)lud (SwePub)ki | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a for2 swepub-publicationtype |
100 | 1 | a Chetelat, G.u University of Caen Normandy4 aut |
245 | 1 0 | a Amyloid-PET and 18-F-FDG-PET in the diagnostic investigation of Alzheimer's disease and other dementias |
264 | 1 | c 2020 |
520 | a Various biomarkers are available to support the diagnosis of neurodegenerative diseases in clinical and research settings. Among the molecular imaging biomarkers, amyloid-PET, which assesses brain amyloid deposition, and F-18-fluorodeoxyglucose (F-18-FDG) PET, which assesses glucose metabolism, provide valuable and complementary information. However, uncertainty remains regarding the optimal timepoint, combination, and an order in which these PET biomarkers should be used in diagnostic evaluations because conclusive evidence is missing. Following an expert panel discussion, we reached an agreement on the specific use of the individual biomarkers, based on available evidence and clinical expertise. We propose a diagnostic algorithm with optimal timepoints for these PET biomarkers, also taking into account evidence from other biomarkers, for early and differential diagnosis of neurodegenerative diseases that can lead to dementia. We propose three main diagnostic pathways with distinct biomarker sequences, in which amyloid-PET and F-18-FDG-PET are placed at different positions in the order of diagnostic evaluations, depending on clinical presentation. We hope that this algorithm can support diagnostic decision making in specialist clinical settings with access to these biomarkers and might stimulate further research towards optimal diagnostic strategies. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Neurovetenskaper0 (SwePub)301052 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Neurosciences0 (SwePub)301052 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Neurologi0 (SwePub)302072 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Neurology0 (SwePub)302072 hsv//eng |
653 | a mild cognitive impairment | |
653 | a progressive supranuclear palsy | |
653 | a cerebrospinal-fluid biomarkers | |
653 | a positron-emission-tomography | |
653 | a differential-diagnosis | |
653 | a clinical-diagnosis | |
653 | a national institute | |
653 | a csf | |
653 | a biomarkers | |
653 | a fdg-pet | |
653 | a a-beta | |
653 | a Neurosciences & Neurology | |
700 | 1 | a Arbizu, J.u University of Navarra,University Clinic of Navarra4 aut |
700 | 1 | a Barthel, H.u University Hospital Leipzig4 aut |
700 | 1 | a Garibotto, V.u University of Geneva,Geneva University Hospital4 aut |
700 | 1 | a Law, I.u Copenhagen University Hospital4 aut |
700 | 1 | a Morbelli, S.u Ospedale Policlinico San Martino,University of California, Berkeley4 aut |
700 | 1 | a van de Giessen, E.u University of Amsterdam,Academic Medical Center of University of Amsterdam (AMC)4 aut |
700 | 1 | a Agosta, F.u Vita-Salute San Raffaele University,San Raffaele Scientific Institute4 aut |
700 | 1 | a Barkhof, F.u University College London,Academic Medical Center of University of Amsterdam (AMC),Vrije Universiteit Amsterdam,Geneva University Hospital,University of Geneva4 aut |
700 | 1 | a Brooks, D. J.u University of Newcastle upon Tyne,Aarhus University Hospital4 aut |
700 | 1 | a Carrillo, M. C.u Alzheimer's Association: Alzheimer's Disease and Dementia4 aut |
700 | 1 | a Dubois, B.u Paris-Sorbonne University,Pitié-Salpêtrière University Hospital4 aut |
700 | 1 | a Fjell, A. M.u Oslo university hospital,University of Oslo4 aut |
700 | 1 | a Frisoni, G. B.4 aut |
700 | 1 | a Hansson, Oskaru Lund University,Lunds universitet,Klinisk minnesforskning,Forskargrupper vid Lunds universitet,Clinical Memory Research,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)mphy-ohn |
700 | 1 | a Herholz, K.u University of Manchester4 aut |
700 | 1 | a Hutton, B. F.u University College London4 aut |
700 | 1 | a Jack, C. R.u Mayo Clinic Minnesota4 aut |
700 | 1 | a Lammertsma, A. A.u Amsterdam UMC - Vrije Universiteit Amsterdam,Vrije Universiteit Amsterdam4 aut |
700 | 1 | a Landau, S. M.u University of Utah4 aut |
700 | 1 | a Minoshima, S.4 aut |
700 | 1 | a Nobili, F.u University of Genoa,Ospedale Policlinico San Martino4 aut |
700 | 1 | a Nordberg, A.u Karolinska Institutet,Karolinska Institute4 aut |
700 | 1 | a Ossenkoppele, Riku Lund University,Lunds universitet,Klinisk minnesforskning,Forskargrupper vid Lunds universitet,Clinical Memory Research,Lund University Research Groups,Vrije Universiteit Amsterdam,Amsterdam UMC - Vrije Universiteit Amsterdam4 aut0 (Swepub:lu)ri1513os |
700 | 1 | a Oyen, W. J. G.u Rijnstate Hospital,Radboud University Medical Center,Humanitas University,Humanitas Research Hospital4 aut |
700 | 1 | a Perani, D.u San Raffaele Hospital,Vita-Salute San Raffaele University4 aut |
700 | 1 | a Rabinovici, G. D.u University of California, San Francisco4 aut |
700 | 1 | a Scheltens, P.u Vrije Universiteit Amsterdam,Amsterdam UMC - Vrije Universiteit Amsterdam4 aut |
700 | 1 | a Villemagne, V. L.u University of Melbourne,Edith Cowan University,Austin Health4 aut |
700 | 1 | a Zetterberg, Henrik,d 1973u University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry,Sahlgrenska University Hospital,University College London4 aut0 (Swepub:lu)med-hiz |
700 | 1 | a Drzezga, A.u University of Cologne,German Center for Neurodegenerative Diseases (DZNE), Bonn,Jülich Research Centre4 aut |
710 | 2 | a University of Caen Normandyb University of Navarra4 org |
773 | 0 | t Lancet Neurologyg 19:11, s. 951-962q 19:11<951-962x 1474-4422x 1474-4465 |
856 | 4 | u http://dx.doi.org/10.1016/S1474-4422(20)30314-8y FULLTEXT |
856 | 4 8 | u https://gup.ub.gu.se/publication/298296 |
856 | 4 8 | u https://doi.org/10.1016/S1474-4422(20)30314-8 |
856 | 4 8 | u https://lup.lub.lu.se/record/a21078b1-2879-44e6-9603-c25a12e5ff86 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:145070034 |
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