Sökning: WFRF:(Björling Alexander) > Time-Resolved X-Ray...
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 04160naa a2200577 4500 | |
001 | oai:gup.ub.gu.se/255758 | |
003 | SwePub | |
008 | 240528s2017 | |||||||||||000 ||eng| | |
024 | 7 | a https://gup.ub.gu.se/publication/2557582 URI |
024 | 7 | a https://doi.org/10.1016/j.str.2017.04.0062 DOI |
040 | a (SwePub)gu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Berntsson, Oskar,d 1989u Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology4 aut0 (Swepub:gu)xboska |
245 | 1 0 | a Time-Resolved X-Ray Solution Scattering Reveals the Structural Photoactivation of a Light-Oxygen-Voltage Photoreceptor |
264 | 1 | b Elsevier BV,c 2017 |
520 | a Light-oxygen-voltage (LOV) receptors are sensory proteins controlling a wide range of organismal adaptations in multiple kingdoms of life. Because of their modular nature, LOV domains are also attractive for use as optogenetic actuators. A flavin chromophore absorbs blue light, forms a bond with a proximal cysteine residue, and induces changes in the surroundings. There is a gap of knowledge on how this initial signal is relayed further through the sensor to the effector module. To characterize these conformational changes, we apply time-resolved X-ray scattering to the homodimeric LOV domain from Bacillus subtilis YtvA. We observe a global structural change in the LOV dimer synchronous with the formation of the chromophore photoproduct state. Using molecular modeling, this change is identified as splaying apart and relative rotation of the two monomers, which leads to an increased separation at the anchoring site of the effector modules. | |
650 | 7 | a NATURVETENSKAPx Biologix Cellbiologi0 (SwePub)106042 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Cell Biology0 (SwePub)106042 hsv//eng |
650 | 7 | a NATURVETENSKAPx Biologix Biokemi och molekylärbiologi0 (SwePub)106022 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Biochemistry and Molecular Biology0 (SwePub)106022 hsv//eng |
653 | a biological macromolecules | |
653 | a bacillus-subtilis | |
653 | a lov2 domains | |
653 | a phototropin | |
653 | a protein | |
653 | a ytva | |
653 | a receptor | |
653 | a flavoprotein | |
653 | a transduction | |
653 | a photocycle | |
700 | 1 | a Diensthuber, R. P.4 aut |
700 | 1 | a Penman, Matthijs R.u Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology4 aut |
700 | 1 | a Björling, Alexander,d 1983u Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology4 aut0 (Swepub:gu)xbjale |
700 | 1 | a Hughes, Ashley J,d 1987u Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology4 aut0 (Swepub:gu)xhugas |
700 | 1 | a Henry, Léocadieu Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology4 aut0 (Swepub:gu)xheleo |
700 | 1 | a Niebling, Stephanu Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology4 aut |
700 | 1 | a Newby, G.4 aut |
700 | 1 | a Liebi, M.4 aut |
700 | 1 | a Menzel, A.4 aut |
700 | 1 | a Henning, R.4 aut |
700 | 1 | a Kosheleva, I.4 aut |
700 | 1 | a Moglich, A.4 aut |
700 | 1 | a Westenhoff, Sebastian,d 1978u Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology4 aut0 (Swepub:gu)xwests |
710 | 2 | a Göteborgs universitetb Institutionen för kemi och molekylärbiologi4 org |
773 | 0 | t Structured : Elsevier BVg 25:6q 25:6x 0969-2126 |
856 | 4 | u http://www.cell.com/article/S0969212617301077/pdf |
856 | 4 8 | u https://gup.ub.gu.se/publication/255758 |
856 | 4 8 | u https://doi.org/10.1016/j.str.2017.04.006 |
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.