WFRF:(Canova F. F.)
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04805naa a2200433 4500 | |
| 001 | oai:DiVA.org:oru-61707 | |
| 003 | SwePub | |
| 008 | 171113s2017 | |||||||||||000 ||eng| | |
| 009 | oai:prod.swepub.kib.ki.se:136976454 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-617072 URI |
| 024 | 7 | a https://doi.org/10.1097/MIB.00000000000010982 DOI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1369764542 URI |
| 040 | a (SwePub)orud (SwePub)ki | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Canova, Cristinau Department of Molecular Medicine, University of Padua, Padua, Italy4 aut |
| 245 | 1 0 | a Inflammatory Bowel Diseases in Children and Young Adults with Celiac Disease :b A Multigroup Matched Comparison |
| 264 | 1 | b Lippincott Williams & Wilkins,c 2017 |
| 338 | a print2 rdacarrier | |
| 500 | a Funding Agency:University of Padua F.S.4.18.01.05 | |
| 520 | a BACKGROUND: Celiac disease (CD) has been linked to inflammatory bowel disease (IBD) but previous reports have been inconsistent and may have been affected by surveillance bias.METHODS: Matched birth cohort study in Friuli-Venezia Giulia Region, Italy. We identified 1294 individuals with CD aged 0 to 23 years at diagnosis using pathology reports, hospital discharge records, or copayment exemptions. Each CD individual was matched with up to 5 general population reference individuals from the regional Medical Birth Register in Friuli-Venezia Giulia (n = 5681). As secondary comparison groups, we used individuals undergoing small intestinal biopsy but not having villous atrophy (either Marsh 0-1-2 or exclusively Marsh 0). Individuals with IBD were identified through hospital discharge records or copayment exemptions. Conditional logistic regression was used to estimate odds ratios (ORs) for having IBD among CD individuals (before or after CD diagnosis) compared with their matched references.RESULTS: Overall 35 individuals with IBD were identified (29 with CD and 6 general population controls). This corresponded to an increased risk of IBD in CD (OR = 24.17; 95% CI, 10.03-58.21). However, compared with individuals with Marsh 0-1-2 the OR decreased to 1.41 (95% CI, 0.91-2.18) and restricting our comparison group to individuals with Marsh 0, the OR was 1.28 (95% CI, 0.61-2.70).CONCLUSIONS: In conclusion, this article found a highly increased risk of IBD in individuals with CD when comparing with the general population. Bias is the likely explanation for the very high risk increase for IBD in CD because the excess risk was substantially lower when we used individuals with a small intestinal biopsy without villous atrophy as our reference. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Gastroenterologi0 (SwePub)302132 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Gastroenterology and Hepatology0 (SwePub)302132 hsv//eng |
| 653 | a Celiac disease | |
| 653 | a inflammatory bowel disease | |
| 653 | a birth cohort | |
| 653 | a matched cohort study | |
| 700 | 1 | a Pitter, Gisellau Department of Molecular Medicine, University of Padua, Padua, Italy; School of Specialization in Hygiene and Preventive Medicine, University of Padua, Padua, Italy4 aut |
| 700 | 1 | a Zanier, Lorisu Epidemiological Service, Udine, Italy4 aut |
| 700 | 1 | a Zanotti, Renzou Department of Molecular Medicine, University of Padua, Padua, Italy4 aut |
| 700 | 1 | a Simonato, Lorenzou Department of Cardiological, Thoracic and Vascular Sciences, University of Padua, Padua, Italy4 aut |
| 700 | 1 | a Ludvigsson, Jonas F.,d 1969-u Karolinska Institutet,Örebro universitet,Institutionen för medicinska vetenskaper,Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Department of Pediatrics, Faculty of Health and Medical Sciences, Örebro University, Örebro, Sweden; Division of Epidemiology and Public Health, School of Medicine, University of Nottingham, Nottingham, United Kingdom; Department of Medicine, College of Physicians and Surgeons, Columbia University, New York NY, USA4 aut0 (Swepub:oru)jsln |
| 710 | 2 | a Department of Molecular Medicine, University of Padua, Padua, Italyb Department of Molecular Medicine, University of Padua, Padua, Italy; School of Specialization in Hygiene and Preventive Medicine, University of Padua, Padua, Italy4 org |
| 773 | 0 | t Inflammatory Bowel Diseasesd : Lippincott Williams & Wilkinsg 23:11, s. 1996-2000q 23:11<1996-2000x 1078-0998x 1536-4844 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-61707 |
| 856 | 4 8 | u https://doi.org/10.1097/MIB.0000000000001098 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:136976454 |
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