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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 06976naa a2201657 4500 | |
| 001 | oai:gup.ub.gu.se/282992 | |
| 003 | SwePub | |
| 008 | 240528s2019 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://gup.ub.gu.se/publication/2829922 URI |
| 024 | 7 | a https://doi.org/10.1161/strokeaha.118.0228562 DOI |
| 040 | a (SwePub)gu | |
| 041 | a eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Altavilla, R.4 aut |
| 245 | 1 0 | a Anticoagulation After Stroke in Patients With Atrial Fibrillation: To Bridge or Not With Low-Molecular-Weight Heparin? |
| 264 | 1 | b Ovid Technologies (Wolters Kluwer Health),c 2019 |
| 520 | a Background and Purpose- Bridging therapy with low-molecular-weight heparin reportedly leads to a worse outcome for acute cardioembolic stroke patients because of a higher incidence of intracerebral bleeding. However, this practice is common in clinical settings. This observational study aimed to compare (1) the clinical profiles of patients receiving and not receiving bridging therapy, (2) overall group outcomes, and (3) outcomes according to the type of anticoagulant prescribed. Methods- We analyzed data of patients from the prospective RAF and RAF-NOACs studies. The primary outcome was defined as the composite of ischemic stroke, transient ischemic attack, systemic embolism, symptomatic cerebral bleeding, and major extracerebral bleeding observed at 90 days after the acute stroke. Results- Of 1810 patients who initiated oral anticoagulant therapy, 371 (20%) underwent bridging therapy with full-dose low-molecular-weight heparin. Older age and the presence of leukoaraiosis were inversely correlated with the use of bridging therapy. Forty-two bridged patients (11.3%) reached the combined outcome versus 72 (5.0%) of the nonbridged patients (P=0.0001). At multivariable analysis, bridging therapy was associated with the composite end point (odds ratio, 2.3; 95% CI, 1.4-3.7; P<0.0001), as well as ischemic (odds ratio, 2.2; 95% CI, 1.3-3.9; P=0.005) and hemorrhagic (odds ratio, 2.4; 95% CI, 1.2-4.9; P=0.01) end points separately. Conclusions- Our findings suggest that patients receiving low-molecular-weight heparin have a higher risk of early ischemic recurrence and hemorrhagic transformation compared with nonbridged patients. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Neurovetenskaper0 (SwePub)301052 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Neurosciences0 (SwePub)301052 hsv//eng |
| 653 | a anticoagulants | |
| 653 | a atrial fibrillation | |
| 653 | a humans | |
| 653 | a incidence | |
| 653 | a secondary prevention | |
| 653 | a acute ischemic-stroke | |
| 653 | a hemorrhagic transformation | |
| 653 | a arterial territories | |
| 653 | a human brain | |
| 653 | a leukoaraiosis | |
| 653 | a metaanalysis | |
| 653 | a outcomes | |
| 653 | a risk | |
| 653 | a Neurosciences & Neurology | |
| 653 | a Cardiovascular System & Cardiology | |
| 700 | 1 | a Caso, V.4 aut |
| 700 | 1 | a Bandini, F.4 aut |
| 700 | 1 | a Agnelli, G.4 aut |
| 700 | 1 | a Tsivgoulis, G.4 aut |
| 700 | 1 | a Yaghi, S.4 aut |
| 700 | 1 | a Furie, K. L.4 aut |
| 700 | 1 | a Tadi, P.4 aut |
| 700 | 1 | a Becattini, C.4 aut |
| 700 | 1 | a Zedde, M.4 aut |
| 700 | 1 | a Abdul-Rahim, A. H.4 aut |
| 700 | 1 | a Lees, K. R.4 aut |
| 700 | 1 | a Alberti, A.4 aut |
| 700 | 1 | a Venti, M.4 aut |
| 700 | 1 | a Acciarresi, M.4 aut |
| 700 | 1 | a D'Amore, C.4 aut |
| 700 | 1 | a Mosconi, M. G.4 aut |
| 700 | 1 | a Cimini, L. A.4 aut |
| 700 | 1 | a Fusaro, J.4 aut |
| 700 | 1 | a Bovi, P.4 aut |
| 700 | 1 | a Carletti, M.4 aut |
| 700 | 1 | a Rigatelli, A.4 aut |
| 700 | 1 | a Cappellari, M.4 aut |
| 700 | 1 | a Putaala, J.4 aut |
| 700 | 1 | a Tomppo, L.4 aut |
| 700 | 1 | a Tatlisumak, Turgutu Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology4 aut0 (Swepub:gu)xtatlt |
| 700 | 1 | a Marcheselli, S.4 aut |
| 700 | 1 | a Pezzini, A.4 aut |
| 700 | 1 | a Poli, L.4 aut |
| 700 | 1 | a Padovani, A.4 aut |
| 700 | 1 | a Masotti, L.4 aut |
| 700 | 1 | a Vannucchi, V.4 aut |
| 700 | 1 | a Sohn, S. I.4 aut |
| 700 | 1 | a Lorenzini, G.4 aut |
| 700 | 1 | a Tassi, R.4 aut |
| 700 | 1 | a Guideri, F.4 aut |
| 700 | 1 | a Acampa, M.4 aut |
| 700 | 1 | a Martini, G.4 aut |
| 700 | 1 | a Ntaios, G.4 aut |
| 700 | 1 | a Athanasakis, G.4 aut |
| 700 | 1 | a Makaritsis, K.4 aut |
| 700 | 1 | a Karagkiozi, E.4 aut |
| 700 | 1 | a Vadikolias, K.4 aut |
| 700 | 1 | a Liantinioti, C.4 aut |
| 700 | 1 | a Chondrogianni, M.4 aut |
| 700 | 1 | a Mumoli, N.4 aut |
| 700 | 1 | a Consoli, D.4 aut |
| 700 | 1 | a Galati, F.4 aut |
| 700 | 1 | a Sacco, S.4 aut |
| 700 | 1 | a Carolei, A.4 aut |
| 700 | 1 | a Tiseo, C.4 aut |
| 700 | 1 | a Corea, F.4 aut |
| 700 | 1 | a Ageno, W.4 aut |
| 700 | 1 | a Bellesini, M.4 aut |
| 700 | 1 | a Silvestrelli, G.4 aut |
| 700 | 1 | a Ciccone, A.4 aut |
| 700 | 1 | a Lanari, A.4 aut |
| 700 | 1 | a Scoditti, U.4 aut |
| 700 | 1 | a Denti, L.4 aut |
| 700 | 1 | a Mancuso, M.4 aut |
| 700 | 1 | a Maccarrone, M.4 aut |
| 700 | 1 | a Ulivi, L.4 aut |
| 700 | 1 | a Orlandi, G.4 aut |
| 700 | 1 | a Giannini, N.4 aut |
| 700 | 1 | a Gialdini, G.4 aut |
| 700 | 1 | a Tassinari, T.4 aut |
| 700 | 1 | a De Lodovici, M. L.4 aut |
| 700 | 1 | a Bono, G.4 aut |
| 700 | 1 | a Rueckert, C.4 aut |
| 700 | 1 | a Baldi, A.4 aut |
| 700 | 1 | a D'Anna, S.4 aut |
| 700 | 1 | a Toni, D.4 aut |
| 700 | 1 | a Letteri, F.4 aut |
| 700 | 1 | a Giuntini, M.4 aut |
| 700 | 1 | a Lotti, E. M.4 aut |
| 700 | 1 | a Flomin, Y.4 aut |
| 700 | 1 | a Pieroni, A.4 aut |
| 700 | 1 | a Kargiotis, O.4 aut |
| 700 | 1 | a Karapanayiotides, T.4 aut |
| 700 | 1 | a Monaco, S.4 aut |
| 700 | 1 | a Baronello, M. M.4 aut |
| 700 | 1 | a Csiba, L.4 aut |
| 700 | 1 | a Szabo, L.4 aut |
| 700 | 1 | a Chiti, A.4 aut |
| 700 | 1 | a Giorli, E.4 aut |
| 700 | 1 | a Del Sette, M.4 aut |
| 700 | 1 | a Imberti, D.4 aut |
| 700 | 1 | a Zabzuni, D.4 aut |
| 700 | 1 | a Doronin, B.4 aut |
| 700 | 1 | a Volodina, V.4 aut |
| 700 | 1 | a Michel, P.4 aut |
| 700 | 1 | a Vanacker, P.4 aut |
| 700 | 1 | a Barlinn, K.4 aut |
| 700 | 1 | a Pallesen, L. P.4 aut |
| 700 | 1 | a Barlinn, J.4 aut |
| 700 | 1 | a Deleu, D.4 aut |
| 700 | 1 | a Melikyan, G.4 aut |
| 700 | 1 | a Ibrahim, F.4 aut |
| 700 | 1 | a Akhtar, N.4 aut |
| 700 | 1 | a Gourbali, V.4 aut |
| 700 | 1 | a Paciaroni, M.4 aut |
| 710 | 2 | a Göteborgs universitetb Institutionen för neurovetenskap och fysiologi4 org |
| 773 | 0 | t Stroked : Ovid Technologies (Wolters Kluwer Health)g 50:8, s. 2093-2100q 50:8<2093-2100x 0039-2499x 1524-4628 |
| 856 | 4 | u https://www.ahajournals.org/doi/pdf/10.1161/STROKEAHA.118.022856 |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/282992 |
| 856 | 4 8 | u https://doi.org/10.1161/strokeaha.118.022856 |
Hitta mer i SwePub
- Av författaren/redakt...
- Altavilla, R.
- Caso, V.
- Bandini, F.
- Agnelli, G.
- Tsivgoulis, G.
- Yaghi, S.
- visa fler...
- Furie, K. L.
- Tadi, P.
- Becattini, C.
- Zedde, M.
- Abdul-Rahim, A. ...
- Lees, K. R.
- Alberti, A.
- Venti, M.
- Acciarresi, M.
- D'Amore, C.
- Mosconi, M. G.
- Cimini, L. A.
- Fusaro, J.
- Bovi, P.
- Carletti, M.
- Rigatelli, A.
- Cappellari, M.
- Putaala, J.
- Tomppo, L.
- Tatlisumak, Turg ...
- Marcheselli, S.
- Pezzini, A.
- Poli, L.
- Padovani, A.
- Masotti, L.
- Vannucchi, V.
- Sohn, S. I.
- Lorenzini, G.
- Tassi, R.
- Guideri, F.
- Acampa, M.
- Martini, G.
- Ntaios, G.
- Athanasakis, G.
- Makaritsis, K.
- Karagkiozi, E.
- Vadikolias, K.
- Liantinioti, C.
- Chondrogianni, M ...
- Mumoli, N.
- Consoli, D.
- Galati, F.
- Sacco, S.
- Carolei, A.
- Tiseo, C.
- Corea, F.
- Ageno, W.
- Bellesini, M.
- Silvestrelli, G.
- Ciccone, A.
- Lanari, A.
- Scoditti, U.
- Denti, L.
- Mancuso, M.
- Maccarrone, M.
- Ulivi, L.
- Orlandi, G.
- Giannini, N.
- Gialdini, G.
- Tassinari, T.
- De Lodovici, M. ...
- Bono, G.
- Rueckert, C.
- Baldi, A.
- D'Anna, S.
- Toni, D.
- Letteri, F.
- Giuntini, M.
- Lotti, E. M.
- Flomin, Y.
- Pieroni, A.
- Kargiotis, O.
- Karapanayiotides ...
- Monaco, S.
- Baronello, M. M.
- Csiba, L.
- Szabo, L.
- Chiti, A.
- Giorli, E.
- Del Sette, M.
- Imberti, D.
- Zabzuni, D.
- Doronin, B.
- Volodina, V.
- Michel, P.
- Vanacker, P.
- Barlinn, K.
- Pallesen, L. P.
- Barlinn, J.
- Deleu, D.
- Melikyan, G.
- Ibrahim, F.
- Akhtar, N.
- Gourbali, V.
- Paciaroni, M.
- visa färre...
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- MEDICIN OCH HÄLSOVETENSKAP
- MEDICIN OCH HÄLS ...
- och Medicinska och f ...
- och Neurovetenskaper
- Artiklar i publikationen
- Stroke
- Av lärosätet
- Göteborgs universitet
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