SwePub
Sök i LIBRIS databas

  Utökad sökning

WFRF:(De Baere E)
 

Sökning: WFRF:(De Baere E) > Development of High...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00006365naa a2200589 4500
001oai:DiVA.org:uu-498936
003SwePub
008230324s2023 | |||||||||||000 ||eng|
009oai:slubar.slu.se:121626
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4989362 URI
0247 a https://doi.org/10.3390/toxins150100372 DOI
0247 a https://res.slu.se/id/publ/1216262 URI
040 a (SwePub)uud (SwePub)slu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a De Baere, Siegridu Univ Ghent, Fac Vet Med, Dept Pathobiol Pharmacol & Zool Med, Lab Pharmacol & Toxicol, Salisburylaan 133, B-9820 Merelbeke, Belgium.4 aut
2451 0a Development of High-Throughput Sample Preparation Procedures for the Quantitative Determination of Aflatoxins in Biological Matrices of Chickens and Cattle Using UHPLC-MS/MS
264 c 2023-01-03
264 1b MDPI,c 2023
338 a electronic2 rdacarrier
520 a Aflatoxins (AFs) frequently contaminate food and animal feeds, especially in (sub) tropical countries. If animals consume contaminated feeds, AFs (mainly aflatoxin B1 (AFB1), B2 (AFB2), G1 (AFG1), G2 (AFG2) and their major metabolites aflatoxin M1 (AFM1) and M2 (AFM2)) can be transferred to edible tissues and products, such as eggs, liver and muscle tissue and milk, which ultimately can reach the human food chain. Currently, the European Union has established a maximum level for AFM1 in milk (0.05 mu g kg(-1)). Dietary adsorbents, such as bentonite clay, have been used to reduce AFs exposure in animal husbandry and carry over to edible tissues and products. To investigate the efficacy of adding bentonite clay to animal diets in reducing the concentration of AFB1, AFB2, AFG1, AFG2, and the metabolites AFM1 and AFM2 in animal-derived foods (chicken muscle and liver, eggs, and cattle milk), chicken and cattle plasma and cattle ruminal fluid, a sensitive and selective ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method has been developed. High-throughput sample preparation procedures were optimized, allowing the analysis of 96 samples per analytical batch and consisted of a liquid extraction using 1% formic acid in acetonitrile, followed by a further clean-up using QuEChERS (muscle tissue), QuEChERS in combination with Oasis((R)) Ostro (liver tissue), Oasis((R)) Ostro (egg, plasma), and Oasis((R)) PRiME HLB (milk, ruminal fluid). The different procedures were validated in accordance with European guidelines. As a proof-of-concept, the final methods were used to successfully determine AFs concentrations in chicken and cattle samples collected during feeding trials for efficacy and safety evaluation of mycotoxin detoxifiers to protect against AFs as well as their carry-over to animal products.
650 7a LANTBRUKSVETENSKAPERx Lantbruksvetenskap, skogsbruk och fiskex Livsmedelsvetenskap0 (SwePub)401032 hsv//swe
650 7a AGRICULTURAL SCIENCESx Agriculture, Forestry and Fisheriesx Food Science0 (SwePub)401032 hsv//eng
650 7a LANTBRUKSVETENSKAPERx Veterinärmedicinx Patobiologi0 (SwePub)403022 hsv//swe
650 7a AGRICULTURAL SCIENCESx Veterinary Sciencex Pathobiology0 (SwePub)403022 hsv//eng
653 a aflatoxins
653 a chicken
653 a cattle
653 a UHPLC-MS/MS
653 a biological matrices
653 a residues
653 a food safety
653 a toxicokinetics
7001 a Ochieng, Phillis E. E.u Univ Ghent, Fac Vet Med, Dept Pathobiol Pharmacol & Zool Med, Lab Pharmacol & Toxicol, Salisburylaan 133, B-9820 Merelbeke, Belgium.;Univ Liege, Lab Food Anal, FARAH Vet Publ Hlth, Ave Cureghem 10, B-4000 Liege, Belgium.4 aut
7001 a Kemboi, David C. C.u Univ Ghent, Fac Vet Med, Dept Pathobiol Pharmacol & Zool Med, Lab Pharmacol & Toxicol, Salisburylaan 133, B-9820 Merelbeke, Belgium.;Univ Nairobi, Fac Vet Med, Dept Vet Pathol Microbiol & Parasitol, POB 29053, Nairobi 00100, Kenya.;Chuka Univ, Dept Anim Sci, POB 109-60400, Kenya 00625, Kenya.4 aut
7001 a Scippo, Marie-Louiseu Univ Liege, Lab Food Anal, FARAH Vet Publ Hlth, Ave Cureghem 10, B-4000 Liege, Belgium.4 aut
7001 a Okoth, Sheilau Univ Nairobi, Fac Sci & Technol, Dept Biol, POB 30197, Nairobi 00100, Kenya.4 aut
7001 a Lindahl, Johannau Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi,Int Livestock Res Inst ILRI, POB30709, Nairobi 00100, Kenya.;Swedish Univ Agr Sci, Dept Clin Sci, SE-75007 Uppsala, Sweden.,Institutionen för kliniska vetenskaper (KV),Department of Clinical Sciences,International Livestock Research Institute (ILRI),Uppsala University4 aut0 (Swepub:slu)49431
7001 a Gathumbi, James K. K.u Univ Nairobi, Fac Vet Med, Dept Vet Pathol Microbiol & Parasitol, POB 29053, Nairobi 00100, Kenya.4 aut
7001 a Antonissen, Guntheru Univ Ghent, Fac Vet Med, Dept Pathobiol Pharmacol & Zool Med, Lab Pharmacol & Toxicol, Salisburylaan 133, B-9820 Merelbeke, Belgium.;Univ Ghent, Fac Vet Med, Chair Poultry Hlth Sci, Salisburylaan 133, B-9820 Merelbeke, Belgium.4 aut
7001 a Croubels, Siskau Univ Ghent, Fac Vet Med, Dept Pathobiol Pharmacol & Zool Med, Lab Pharmacol & Toxicol, Salisburylaan 133, B-9820 Merelbeke, Belgium.4 aut
7102 a Univ Ghent, Fac Vet Med, Dept Pathobiol Pharmacol & Zool Med, Lab Pharmacol & Toxicol, Salisburylaan 133, B-9820 Merelbeke, Belgium.b Univ Ghent, Fac Vet Med, Dept Pathobiol Pharmacol & Zool Med, Lab Pharmacol & Toxicol, Salisburylaan 133, B-9820 Merelbeke, Belgium.;Univ Liege, Lab Food Anal, FARAH Vet Publ Hlth, Ave Cureghem 10, B-4000 Liege, Belgium.4 org
7102 a Sveriges lantbruksuniversitet
7730 t Toxinsd : MDPIg 15:1q 15:1x 2072-6651
8564 u https://doi.org/10.3390/toxins15010037y Fulltext
8564 u https://uu.diva-portal.org/smash/get/diva2:1745706/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 u https://pub.epsilon.slu.se/id/eprint/30465/contentsx primaryx Raw objectx freey FULLTEXT
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-498936
8564 8u https://doi.org/10.3390/toxins15010037
8564 8u https://res.slu.se/id/publ/121626

Hitta via bibliotek

  • Toxins (Sök värdpublikationen i LIBRIS)

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy