WFRF:(Fowkes F. Gerry R.)
Sökning: WFRF:(Fowkes F. Gerry R.) > A Structured Review...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04396naa a2200445 4500 | |
| 001 | oai:lup.lub.lu.se:28a6923d-981f-42f0-ae16-4bbe5d9fdba3 | |
| 003 | SwePub | |
| 008 | 170811s2017 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://lup.lub.lu.se/record/28a6923d-981f-42f0-ae16-4bbe5d9fdba32 URI |
| 024 | 7 | a https://doi.org/10.1161/CIRCULATIONAHA.117.0244692 DOI |
| 040 | a (SwePub)lu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a for2 swepub-publicationtype |
| 072 | 7 | a ref2 swepub-contenttype |
| 100 | 1 | a Hess, Connie N.u University of Colorado School of Medicine4 aut |
| 245 | 1 0 | a A Structured Review of Antithrombotic Therapy in Peripheral Artery Disease with a Focus on Revascularization : A TASC (InterSociety Consensus for the Management of Peripheral Artery Disease) Initiative |
| 264 | 1 | c 2017 |
| 300 | a 22 s. | |
| 520 | a Peripheral artery disease affects >200 million people worldwide and is associated with significant limb and cardiovascular morbidity and mortality. Limb revascularization is recommended to improve function and quality of life for symptomatic patients with peripheral artery disease with intermittent claudication who have not responded to medical treatment. For patients with critical limb ischemia, the goals of revascularization are to relieve pain, help wound healing, and prevent limb loss. The baseline risk of cardiovascular and limb-related events demonstrated among patients with stable peripheral artery disease is elevated after revascularization and related to atherothrombosis and restenosis. Both of these processes involve platelet activation and the coagulation cascade, forming the basis for the use of antiplatelet and anticoagulant therapies to optimize procedural success and reduce postprocedural cardiovascular risk. Unfortunately, few high-quality, randomized data to support use of these therapies after peripheral artery disease revascularization exist, and much of the rationale for the use of antiplatelet agents after endovascular peripheral revascularization is extrapolated from percutaneous coronary intervention literature. Consequently, guideline recommendations for antithrombotic therapy after lower limb revascularization are inconsistent and not always evidence-based. In this context, the purpose of this structured review is to assess the available randomized data for antithrombotic therapy after peripheral arterial revascularization, with a focus on clinical trial design issues that may affect interpretation of study results, and highlight areas that require further investigation. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng |
| 653 | a antithrombotic | |
| 653 | a peripheral artery disease | |
| 653 | a revascularization | |
| 700 | 1 | a Norgren, Larsu Lund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Department of Clinical Sciences, Malmö,Faculty of Medicine4 aut0 (Swepub:lu)kir-lno |
| 700 | 1 | a Ansel, Gary M.u Örebro University4 aut |
| 700 | 1 | a Capell, Warren H.u University of Colorado School of Medicine4 aut |
| 700 | 1 | a Fletcher, John P.u University of Colorado School of Medicine4 aut |
| 700 | 1 | a Fowkes, F. Gerry R.u University of Sydney4 aut |
| 700 | 1 | a Gottsäter, Andersu Lund University,Lunds universitet,Vaskulära sjukdomar - kliniska studier,Forskargrupper vid Lunds universitet,Vascular Diseases - Clinical Research,Lund University Research Groups,University of Edinburgh4 aut0 (Swepub:lu)medf-ago |
| 700 | 1 | a Hitos, Kerryu Skåne University Hospital,Lund University4 aut |
| 700 | 1 | a Jaff, Michael R.u University of Sydney4 aut |
| 700 | 1 | a Nordanstig, Joakimu Harvard Medical School4 aut |
| 700 | 1 | a Hiatt, William R.u University of Colorado School of Medicine,Sahlgrenska University Hospital4 aut |
| 710 | 2 | a University of Colorado School of Medicineb Institutionen för kliniska vetenskaper, Malmö4 org |
| 773 | 0 | t Circulationg 135:25, s. 2534-2555q 135:25<2534-2555x 0009-7322 |
| 856 | 4 | u http://dx.doi.org/10.1161/CIRCULATIONAHA.117.024469y FULLTEXT |
| 856 | 4 8 | u https://lup.lub.lu.se/record/28a6923d-981f-42f0-ae16-4bbe5d9fdba3 |
| 856 | 4 8 | u https://doi.org/10.1161/CIRCULATIONAHA.117.024469 |
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