Sökning: WFRF:(Fung S. Y.) > (2020-2024) > Adjusted estimate o...
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000 | 08936naa a2201957 4500 | |
001 | oai:gup.ub.gu.se/336397 | |
003 | SwePub | |
008 | 240528s2024 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:155340775 | |
024 | 7 | a https://gup.ub.gu.se/publication/3363972 URI |
024 | 7 | a https://doi.org/10.1016/j.jhep.2023.10.0432 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1553407752 URI |
040 | a (SwePub)gud (SwePub)ki | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Razavi-Shearer, Devin M.4 aut |
245 | 1 0 | a Adjusted estimate of the prevalence of hepatitis delta virus in 25 countries and territories |
264 | 1 | c 2024 |
520 | a Background & Aims: Hepatitis delta virus (HDV) is a satellite RNA virus that requires the hepatitis B virus (HBV) for assembly and propagation. Individuals infected with HDV progress to advanced liver disease faster than HBV-monoinfected individuals. Recent studies have estimated the global prevalence of anti-HDV antibodies among the HBV-infected population to be 5-15%. This study aimed to better understand HDV prevalence at the population level in 25 countries/territories. Methods: We conducted a literature review to determine the prevalence of anti-HDV and HDV RNA in hepatitis B surface antigen (HBsAg)-positive individuals in 25 countries/territories. Virtual meetings were held with experts from each setting to discuss the findings and collect unpublished data. Data were weighted for patient segments and regional heterogeneity to estimate the prevalence in the HBV-infected population. The findings were then combined with The Polaris Observatory HBV data to estimate the anti-HDV and HDV RNA prevalence in each country/territory at the population level. Results: After adjusting for geographical distribution, disease stage and special populations, the anti-HDV prevalence among the HBsAg+ population changed from the literature estimate in 19 countries. The highest anti-HDV prevalence was 60.1% in Mongolia. Once adjusted for the size of the HBsAg+ population and HDV RNA positivity rate, China had the highest absolute number of HDV RNA+ cases. Conclusions: We found substantially lower HDV prevalence than previously reported, as prior meta-analyses primarily focused on studies conducted in groups/regions that have a higher probability of HBV infection: tertiary care centers, specific risk groups or geographical regions. There is large uncertainty in HDV prevalence estimates. The implementation of reflex testing would improve estimates, while also allowing earlier linkage to care for HDV RNA+ individuals. The logistical and economic burden of reflex testing on the health system would be limited, as only HBsAg+ cases would be screened. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Gastroenterologi0 (SwePub)302132 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Gastroenterology and Hepatology0 (SwePub)302132 hsv//eng |
700 | 1 | a Buti, Maria4 aut |
700 | 1 | a Tacke, Frank4 aut |
700 | 1 | a Terrault, Norah A.4 aut |
700 | 1 | a Zeuzem, Stefan4 aut |
700 | 1 | a Abbas, Zaigham4 aut |
700 | 1 | a Aghemo, Alessio4 aut |
700 | 1 | a Akarca, Ulus S.4 aut |
700 | 1 | a Al Masri, Nasser M.4 aut |
700 | 1 | a Alalwan, Abduljaleel M.4 aut |
700 | 1 | a Blome, Marianne Alanko4 aut |
700 | 1 | a Aleman, Soou Karolinska Institutet4 aut |
700 | 1 | a Alghamdi, Abdullah S.4 aut |
700 | 1 | a Alghamdi, Mohammed4 aut |
700 | 1 | a Alghamdi, Saad4 aut |
700 | 1 | a Al-Hamoudi, Waleed K.4 aut |
700 | 1 | a Ali, Ela4 aut |
700 | 1 | a Aljumah, Abdulrahman A.4 aut |
700 | 1 | a Altraif, Ibrahim H.4 aut |
700 | 1 | a Amarsanaa, Jazag4 aut |
700 | 1 | a Asselah, Tarik4 aut |
700 | 1 | a Baatarkhuu, Oidov4 aut |
700 | 1 | a Babameto, Adriana4 aut |
700 | 1 | a Ben-Ari, Ziv4 aut |
700 | 1 | a Berg, Thomas4 aut |
700 | 1 | a Biondi, Mia J.4 aut |
700 | 1 | a Braga, Wornei S. M.4 aut |
700 | 1 | a Brandao-Mello, Carlos E.4 aut |
700 | 1 | a Jr, Robert S. Brown4 aut |
700 | 1 | a Brunetto, Maurizia R.4 aut |
700 | 1 | a Cabezas, Joaquin4 aut |
700 | 1 | a Cardoso, Mariana4 aut |
700 | 1 | a Chan, Henry Lik Yuen4 aut |
700 | 1 | a Cheinquer, Hugo4 aut |
700 | 1 | a Chen, Chien-Jen4 aut |
700 | 1 | a Chen, Pei-Jer4 aut |
700 | 1 | a Chien, Cheng-Hung4 aut |
700 | 1 | a Child, Hailey4 aut |
700 | 1 | a Chuang, Wan-Long4 aut |
700 | 1 | a Garza, Laura E. Cisneros4 aut |
700 | 1 | a Coco, Barbara4 aut |
700 | 1 | a Coffin, Carla S.4 aut |
700 | 1 | a Coppola, Nicola4 aut |
700 | 1 | a Cornberg, Markus4 aut |
700 | 1 | a Craxi, Antonio4 aut |
700 | 1 | a Crespo, Javier4 aut |
700 | 1 | a Cuko, Liri4 aut |
700 | 1 | a De Ledinghen, Victor4 aut |
700 | 1 | a Duberg, Ann-Sofi4 aut |
700 | 1 | a Etzion, Ohad4 aut |
700 | 1 | a Ferraz, Maria Lucia G.4 aut |
700 | 1 | a Ferreira, Paulo R. A.4 aut |
700 | 1 | a Forns, Xavier4 aut |
700 | 1 | a Foster, Graham R.4 aut |
700 | 1 | a Fung, James4 aut |
700 | 1 | a Gaeta, Giovanni B.4 aut |
700 | 1 | a Garcia-Samaniego, Javier4 aut |
700 | 1 | a Genov, Jordan4 aut |
700 | 1 | a Gheorghe, Liliana S.4 aut |
700 | 1 | a Gholam, Pierre M.4 aut |
700 | 1 | a Gish, Robert G.4 aut |
700 | 1 | a Glenn, Jeffrey4 aut |
700 | 1 | a Goldis, Adrian4 aut |
700 | 1 | a Hamid, Saeed S.4 aut |
700 | 1 | a Hercun, Julian4 aut |
700 | 1 | a Hsu, Yao-Chun4 aut |
700 | 1 | a Hu, Ching-Chih4 aut |
700 | 1 | a Huang, Jee-Fu4 aut |
700 | 1 | a Idilman, Ramazan4 aut |
700 | 1 | a Jafri, Wasim S. M.4 aut |
700 | 1 | a Janjua, Naveed4 aut |
700 | 1 | a Jelev, Deian4 aut |
700 | 1 | a Jerkeman, Anna4 aut |
700 | 1 | a Jia, Jidong4 aut |
700 | 1 | a Kaberg, Martin4 aut |
700 | 1 | a Kaita, Kelly D. E.4 aut |
700 | 1 | a Kao, Jia-Horng4 aut |
700 | 1 | a Khan, Aamir G.4 aut |
700 | 1 | a Kim, Do Young4 aut |
700 | 1 | a Kondili, Loreta A.4 aut |
700 | 1 | a Lagging, Martin,d 1965u Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för infektionssjukdomar,Institute of Biomedicine, Department of Infectious Medicine4 aut0 (Swepub:gu)xlagma |
700 | 1 | a Lampertico, Pietro4 aut |
700 | 1 | a Lazaro, Pablo4 aut |
700 | 1 | a Lazarus, Jeffrey4 aut |
700 | 1 | a Lee, Mei-Hsuan4 aut |
700 | 1 | a Lim, Young-Suk4 aut |
700 | 1 | a Lobato, Cirley M. O.4 aut |
700 | 1 | a Macedo, Guilherme4 aut |
700 | 1 | a Marinho, Rui T.4 aut |
700 | 1 | a Marotta, Paul J.4 aut |
700 | 1 | a Martins, Alexanda4 aut |
700 | 1 | a Mendes-Correa, Maria Cassia4 aut |
700 | 1 | a Mendez-Sanchez, Nahum4 aut |
700 | 1 | a Navas, Maria-Cristina4 aut |
700 | 1 | a Ning, Qing4 aut |
700 | 1 | a Ormeci, Necati4 aut |
700 | 1 | a Orrego, Mauricio4 aut |
700 | 1 | a Osiowy, Carla4 aut |
700 | 1 | a Pan, Calvin Q.4 aut |
700 | 1 | a Pessoa, Mario G.4 aut |
700 | 1 | a Piracha, Zahra Z.4 aut |
700 | 1 | a Pop, Cora4 aut |
700 | 1 | a Ramos, Jose A. Presa4 aut |
700 | 1 | a Qureshi, Huma4 aut |
700 | 1 | a Raimondo, Giovanni4 aut |
700 | 1 | a Ramji, Alnoor4 aut |
700 | 1 | a Razavi-Shearer, Kathryn4 aut |
700 | 1 | a Ribeiro, Sofia4 aut |
700 | 1 | a Rios-Hincapie, Cielo Y.4 aut |
700 | 1 | a Rodriguez, Manuel4 aut |
700 | 1 | a Rosenberg, William M. C.4 aut |
700 | 1 | a Roulot, Dominique4 aut |
700 | 1 | a Ryder, Stephen D.4 aut |
700 | 1 | a Saeed, Umar4 aut |
700 | 1 | a Safadi, Rifaat4 aut |
700 | 1 | a Sanai, Faisal M.4 aut |
700 | 1 | a Sanchez-Avila, Juan F.4 aut |
700 | 1 | a Santantonio, Teresa A.4 aut |
700 | 1 | a Sarrazin, Christoph4 aut |
700 | 1 | a Seto, Wai-Kay4 aut |
700 | 1 | a Shouval, Daniel4 aut |
700 | 1 | a Simonova, Marieta Y.4 aut |
700 | 1 | a Tanaka, Junko4 aut |
700 | 1 | a Tergast, Tammo L.4 aut |
700 | 1 | a Tsendsuren, Oyunsuren4 aut |
700 | 1 | a Valente, Cristina4 aut |
700 | 1 | a Villalobos-Salcedo, Juan Miguel4 aut |
700 | 1 | a Voeller, Alexis S.4 aut |
700 | 1 | a Waheed, Yasir4 aut |
700 | 1 | a Wong, Grace L-H4 aut |
700 | 1 | a Wong, Vincent W-S4 aut |
700 | 1 | a Wu, Jaw-Ching4 aut |
700 | 1 | a Yang, Hwai-4 aut |
700 | 1 | a Yip, Terry C-F4 aut |
700 | 1 | a Yu, Ming-Lung4 aut |
700 | 1 | a Yuen, Man-Fung4 aut |
700 | 1 | a Yurdaydin, Cihan4 aut |
700 | 1 | a Zuckerman, Eli4 aut |
700 | 1 | a Razavi, Homie A.4 aut |
710 | 2 | a Karolinska Institutetb Institutionen för biomedicin, avdelningen för infektionssjukdomar4 org |
773 | 0 | t JOURNAL OF HEPATOLOGYg 80:2, s. 232-242q 80:2<232-242x 0168-8278x 1600-0641 |
856 | 4 8 | u https://gup.ub.gu.se/publication/336397 |
856 | 4 8 | u https://doi.org/10.1016/j.jhep.2023.10.043 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:155340775 |
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