Sökning: WFRF:(Jepsen P) > The severity of hum...
Fältnamn | Indikatorer | Metadata |
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000 | 03846naa a2200565 4500 | |
001 | oai:DiVA.org:hkr-18790 | |
003 | SwePub | |
008 | 181024s2018 | |||||||||||000 ||eng| | |
024 | 7 | a urn:nbn:se:hkr:diva-187902 urn |
024 | 7 | a https://doi.org/10.1111/jcpe.130232 DOI |
040 | a (SwePub)hkr | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Kröger, Au Tyskland & England4 aut |
245 | 1 0 | a The severity of human peri-implantitis lesions correlates with the level of submucosal microbial sysbiosis |
264 | 1 | c 2018 |
338 | a print2 rdacarrier | |
520 | a AIM: To cross-sectionally analyze the submucosal microbiome of peri-implantitis (PI) lesions at different severity levels.MATERIALS AND METHODS: Microbial signatures of 45 submucosal plaque samples from untreated peri-implantitis lesions obtained from 30 non-smoking, systemically healthy subjects were assessed by 16s sequencing. Linear mixed models were used to identify taxa with differential abundance by probing depth, after correction for age, gender, and multiple samples per subject. Network analyses were performed to identify groups of taxa with mutual occurrence or exclusion. Subsequently, the effects of peri-implant probing depth on submucosal microbial dysbiosis was calculated using the microbial dysbiosis index.RESULTS: In total, we identified 337 different taxa in the submucosal microbiome of peri-implantitis. Total abundance of 12 taxa correlated significantly with increasing probing depth; a significant relationship with lower probing depth was found for 16 taxa. Network analysis identified two mutually exclusive complexes associated with shallow pockets and deeper pockets, respectively. Deeper peri-implant pockets were associated with significantly increased dysbiosis.CONCLUSION: Increases in peri-implant pocket depth are associated with substantial changes in the submucosal microbiome and increasing levels of dysbiosis. This article is protected by copyright. All rights reserved. | |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Dentistry0 (SwePub)302162 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Odontologi0 (SwePub)302162 hsv//swe |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicin0 (SwePub)3022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicine0 (SwePub)3022 hsv//eng |
653 | a NGS | |
653 | a 16s | |
653 | a dysbiosis | |
653 | a microbiome | |
653 | a next generation sequencing | |
653 | a peri-implant disease | |
653 | a peri-implantitis | |
700 | 1 | a Hülsmann, Cu Tyskland4 aut |
700 | 1 | a Fickl, Su Tyskland4 aut |
700 | 1 | a Spinell, Tu Tyskland & Italien4 aut |
700 | 1 | a Hüttig, Fu Tyskland4 aut |
700 | 1 | a Kaufmann, Fu Tyskland4 aut |
700 | 1 | a Heimbach, Au Tyskland4 aut |
700 | 1 | a Hoffmann, Pu Tyskland4 aut |
700 | 1 | a Enkling, Nu Tyskland4 aut |
700 | 1 | a Renvert, Stefanu Högskolan Kristianstad,Forskningsmiljön Oral Hälsa - Allmänhälsa - Livskvalitet (OHAL),Avdelningen för oral hälsa4 aut0 (Swepub:hkr)res |
700 | 1 | a Schwarz, Fu Tyskland4 aut |
700 | 1 | a Demmer, Ryan Tu USA4 aut |
700 | 1 | a Papapanou, P Nu USA4 aut |
700 | 1 | a Jepsen, Su Tyskland4 aut |
700 | 1 | a Kebschull, Mu USA & Tyskland4 aut |
710 | 2 | a Tyskland & Englandb Tyskland4 org |
773 | 0 | t Journal of Clinical Periodontologyg 45:12, s. 1498-1509q 45:12<1498-1509x 0303-6979x 1600-051X |
856 | 4 | u http://pure-oai.bham.ac.uk/ws/files/55827295/Kroeger_et_al_The_severity_of_human_Journal_of_Clinical_Periodontology_2018.pdf |
856 | 4 8 | u http://urn.kb.se/resolve?urn=urn:nbn:se:hkr:diva-18790x lärosäteslänky Till lärosätets (hkr) databas |
856 | 4 8 | u https://doi.org/10.1111/jcpe.13023 |
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