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Femtosecond dark-field imaging with an X-ray free electron laser

Martin, A. V. (author)
Loh, N. D. (author)
Hampton, C. Y. (author)
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Sierra, R. G. (author)
Wang, F. (author)
Aquila, A. (author)
Bajt, S. (author)
Barthelmess, M. (author)
Bostedt, C. (author)
Bozek, J. D. (author)
Coppola, N. (author)
Epp, S. W. (author)
Erk, B. (author)
Fleckenstein, H. (author)
Foucar, L. (author)
Frank, M. (author)
Graafsma, H. (author)
Gumprecht, L. (author)
Hartmann, A. (author)
Hartmann, R. (author)
Hauser, G. (author)
Hirsemann, H. (author)
Holl, P. (author)
Kassemeyer, S. (author)
Kimmel, N. (author)
Liang, M. (author)
Lomb, L. (author)
Maia, F. R. N. C. (author)
NERSC, Lawrence Berkeley National Laboratory, Berkeley,California 94720, USA
Marchesini, S. (author)
Nass, K. (author)
Pedersoli, E. (author)
Reich, C. (author)
Rolles, D. (author)
Rudek, B. (author)
Rudenko, A. (author)
Schulz, J. (author)
Shoeman, R. L. (author)
Soltau, H. (author)
Starodub, D. (author)
Steinbrener, J. (author)
Stellato, F. (author)
Strüder, L. (author)
Ullrich, J. (author)
Weidenspointner, G. (author)
White, T. A. (author)
Wunderer, C. B. (author)
Barty, A. (author)
Schlichting, I. (author)
Bogan, M. J. (author)
Chapman, H. N. (author)
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 (creator_code:org_t)
2012
2012
English.
In: Optics Express. - 1094-4087. ; 20:12, s. 13501-13512
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • The emergence of femtosecond diffractive imaging with X-ray lasers has enabled pioneering structural studies of isolated particles, such as viruses, at nanometer length scales. However, the issue of missing low frequency data significantly limits the potential of X-ray lasers to reveal sub-nanometer details of micrometer-sized samples. We have developed a new technique of dark-field coherent diffractive imaging to simultaneously overcome the missing data issue and enable us to harness the unique contrast mechanisms available in dark-field microscopy. Images of airborne particulate matter (soot) up to two microns in length were obtained using single-shot diffraction patterns obtained at the Linac Coherent Light Source, four times the size of objects previously imaged in similar experiments. This technique opens the door to femtosecond diffractive imaging of a wide range of micrometer-sized materials that exhibit irreproducible complexity down to the nanoscale, including airborne particulate matter, small cells, bacteria and gold-labeled biological samples.

Subject headings

NATURVETENSKAP  -- Fysik -- Atom- och molekylfysik och optik (hsv//swe)
NATURAL SCIENCES  -- Physical Sciences -- Atom and Molecular Physics and Optics (hsv//eng)

Keyword

X-ray imaging
Image reconstruction techniques

Publication and Content Type

ref (subject category)
art (subject category)

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