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Sökning: WFRF:(Lindkvist Björn) > (2015-2019) > Helicobacter pylori...

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FältnamnIndikatorerMetadata
00007989naa a2200949 4500
001oai:lup.lub.lu.se:bafd527b-45e1-47c0-a249-ba540613416f
003SwePub
008170313s2017 | |||||||||||000 ||eng|
009oai:DiVA.org:umu-133732
009oai:prod.swepub.kib.ki.se:135414701
0247 a https://lup.lub.lu.se/record/bafd527b-45e1-47c0-a249-ba540613416f2 URI
0247 a https://doi.org/10.1002/ijc.305902 DOI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1337322 URI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1354147012 URI
040 a (SwePub)lud (SwePub)umud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a Huang, Jiaqiu Karolinska Institute4 aut
2451 0a Helicobacter pylori infection, chronic corpus atrophic gastritis and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort : A nested case-control study
264 c 2017-02-23
264 1b Wiley,c 2017
300 a 9 s.
520 a The association between H. pylori infection and pancreatic cancer risk remains controversial. We conducted a nested case-control study with 448 pancreatic cancer cases and their individually matched control subjects, based on the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort, to determine whether there was an altered pancreatic cancer risk associated with H. pylori infection and chronic corpus atrophic gastritis. Conditional logistic regression models were applied to calculate odds ratios (ORs) and corresponding 95% confidence intervals (CIs), adjusted for matching factors and other potential confounders. Our results showed that pancreatic cancer risk was neither associated with H. pylori seropositivity (OR = 0.96; 95% CI: 0.70, 1.31) nor CagA seropositivity (OR = 1.07; 95% CI: 0.77, 1.48). We also did not find any excess risk among individuals seropositive for H. pylori but seronegative for CagA, compared with the group seronegative for both antibodies (OR = 0.94; 95% CI: 0.63, 1.38). However, we found that chronic corpus atrophic gastritis was non-significantly associated with an increased pancreatic cancer risk (OR = 1.35; 95% CI: 0.77, 2.37), and although based on small numbers, the excess risk was particularly marked among individuals seronegative for both H. pylori and CagA (OR = 5.66; 95% CI: 1.59, 20.19, p value for interaction < 0.01). Our findings provided evidence supporting the null association between H. pylori infection and pancreatic cancer risk in western European populations. However, the suggested association between chronic corpus atrophic gastritis and pancreatic cancer risk warrants independent verification in future studies, and, if confirmed, further studies on the underlying mechanisms.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
653 a chronic corpus atrophic gastritis
653 a EPIC cohort
653 a H. pylori infection
653 a nested case-control study
653 a pancreatic cancer risk
653 a H. pylori infection
7001 a Zagai, Ulrikau Karolinska Institutet,Karolinska Institute4 aut
7001 a Hallmans, Göranu Umeå universitet,Umeå University,Institutionen för kostvetenskap4 aut0 (Swepub:umu)goha0001
7001 a Nyrén, Olofu Karolinska Institute4 aut
7001 a Engstrand, Larsu Karolinska Institutet,Karolinska Institute4 aut
7001 a Stolzenberg-Solomon, Rachaelu National Cancer Institute, USA4 aut
7001 a Duell, Eric Ju Catalan Institute of Oncology4 aut
7001 a Overvad, Kimu Aarhus University4 aut
7001 a Katzke, Verena Au German Cancer Research Centre,Bellvitge University Hospital-IDIBELL4 aut
7001 a Kaaks, Rudolfu German Cancer Research Centre4 aut
7001 a Jenab, Mazdau International Agency for Research on Cancer, World Health Organization4 aut
7001 a Park, Jin Youngu International Agency for Research on Cancer, World Health Organization4 aut
7001 a Murillo, Raulu International Agency for Research on Cancer, World Health Organization4 aut
7001 a Trichopoulou, Antoniau National and Kapodistrian University of Athens,Hellenic Health Foundation, Athens4 aut
7001 a Lagiou, Pagonau Harvard University,National and Kapodistrian University of Athens,Hellenic Health Foundation, Athens4 aut
7001 a Bamia, Christinau Hellenic Health Foundation, Athens,National and Kapodistrian University of Athens4 aut
7001 a Bradbury, Kathryn Eu University of Oxford4 aut
7001 a Riboli, Eliou Imperial College London4 aut
7001 a Aune, Dagfinnu Imperial College London4 aut
7001 a Tsilidis, Konstantinos K.u University of Ioannina,Imperial College London4 aut
7001 a Capellá, Gabrielu Catalan Institute of Oncology4 aut
7001 a Agudo, Antoniou Bellvitge University Hospital-IDIBELL4 aut
7001 a Krogh, Vittoriou Istituto Nazionale dei Tumori4 aut
7001 a Palli, Domenicou Cancer Research and Prevention Institute (ISPO)4 aut
7001 a Panico, Salvatoreu University of Naples Federico II4 aut
7001 a Weiderpass, Elisabeteu Karolinska Institutet,Karolinska Institute,Folkhälsan Research Center,Cancer Registry of Norway, Institute of Population-Based Cancer Research,UiT The Arctic University of Norway, Tromsø4 aut
7001 a Tjønneland, Anneu Danish Cancer Society4 aut
7001 a Olsen, Anjau Danish Cancer Society4 aut
7001 a Martínez, Begoñau Andalusian School Of Public Health (EASP)4 aut
7001 a Redondo-Sanchez, Danielu Andalusian School Of Public Health (EASP),CIBER Epidemiology and Public Health (CIBERESP),University of Granada4 aut
7001 a Chirlaque, Maria Doloresu CIBER Epidemiology and Public Health (CIBERESP),Murcia Regional Health Council,University of Murcia4 aut
7001 a HM Peeters, Petrau University Medical Center Utrecht4 aut
7001 a Regnér, Sarau Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups4 aut0 (Swepub:lu)kir-sre
7001 a Lindkvist, Björnu Sahlgrenska University Hospital4 aut0 (Swepub:lu)kir-bl0
7001 a Naccarati, Alessiou Human Genetics Foundation (HuGeF)4 aut
7001 a Ardanaz, Evau CIBER Epidemiology and Public Health (CIBERESP),Health Research Institute of Navarra (IDISNA)4 aut0 (Swepub:lu)extLU-05
7001 a Larrañaga, Nereau CIBER Epidemiology and Public Health (CIBERESP)4 aut
7001 a Boutron-Ruault, Marie-Christineu University of Paris-Saclay,Institut Gustave Roussy,Centre for Research in Epidemiology and Population Health (CESP)4 aut
7001 a Rebours, Vincianeu Paris Diderot University4 aut
7001 a Barré, Amélieu University of Paris-Saclay4 aut
7001 a Bueno-De-Mesquita, Bas H.u University Medical Center Utrecht,Imperial College London,National Institute for Public Health and the Environment (RIVM),University of Malaya4 aut
7001 a Ye, Weiminu Karolinska Institutet,Umeå University,Karolinska Institute4 aut
7102 a Karolinska Institutetb Karolinska Institute4 org
7730 t International Journal of Cancerd : Wileyg 140:8, s. 1727-1735q 140:8<1727-1735x 0020-7136x 1097-0215
8564 u http://dx.doi.org/10.1002/ijc.30590y FULLTEXT
8564 u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijc.30590
8564 8u https://lup.lub.lu.se/record/bafd527b-45e1-47c0-a249-ba540613416f
8564 8u https://doi.org/10.1002/ijc.30590
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-133732
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:135414701

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