WFRF:(Mallone R)
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 02677naa a2200397 4500 | |
| 001 | oai:lup.lub.lu.se:bab634ab-27c0-40be-a5e7-d972fb55936a | |
| 003 | SwePub | |
| 008 | 160404s2010 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://lup.lub.lu.se/record/16881662 URI |
| 024 | 7 | a https://doi.org/10.1111/j.1365-2249.2010.04237.x2 DOI |
| 040 | a (SwePub)lu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a art2 swepub-publicationtype |
| 072 | 7 | a ref2 swepub-contenttype |
| 100 | 1 | a Mannering, S I4 aut |
| 245 | 1 0 | a Current approaches to measuring human islet-antigen specific T cell function in type 1 diabetes. |
| 264 | c 2010-09-15 | |
| 264 | 1 | b Oxford University Press (OUP),c 2010 |
| 520 | a Type 1 diabetes (T1D) is an autoimmune disease caused by the T cell-mediated destruction of the pancreatic insulin-producing beta cells. Currently there are no widely accepted and standardized assays available to analyse the function of autoreactive T cells involved in T1D. The development of such an assay would greatly aid efforts to understand the pathogenesis of T1D and is also urgently required to guide the development of antigen-based therapies intended to prevent, or cure, T1D. Here we describe some of the assays used currently to detect autoreactive T cells in human blood and review critically their strengths and weaknesses. The challenges and future prospects for the T cell assays are discussed. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Immunologi inom det medicinska området0 (SwePub)301102 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Immunology in the medical area0 (SwePub)301102 hsv//eng |
| 700 | 1 | a Wong, F S4 aut |
| 700 | 1 | a Durinovic-Belló, I4 aut |
| 700 | 1 | a Brooks-Worrell, B4 aut |
| 700 | 1 | a Tree, T I4 aut |
| 700 | 1 | a Cilio, Corradou Lund University,Lunds universitet,Diabetes - immunovirologi,Forskargrupper vid Lunds universitet,Diabetes - Immunovirology,Lund University Research Groups4 aut0 (Swepub:lu)endo-cci |
| 700 | 1 | a Schloot, N C4 aut |
| 700 | 1 | a Mallone, R4 aut |
| 710 | 2 | a Diabetes - immunovirologib Forskargrupper vid Lunds universitet4 org |
| 773 | 0 | t Clinical and Experimental Immunologyd : Oxford University Press (OUP)g okt, s. 197-209q okt<197-209x 0009-9104x 1365-2249 |
| 856 | 4 | u http://www.ncbi.nlm.nih.gov/pubmed/20846160?dopt=Abstracty FULLTEXT |
| 856 | 4 | u http://dx.doi.org/10.1111/j.1365-2249.2010.04237.xy FULLTEXT |
| 856 | 4 | u https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996587 |
| 856 | 4 8 | u https://lup.lub.lu.se/record/1688166 |
| 856 | 4 8 | u https://doi.org/10.1111/j.1365-2249.2010.04237.x |
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