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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00002540naa a2200373 4500
001oai:DiVA.org:uu-202979
003SwePub
008130701s2013 | |||||||||||000 ||eng|
024a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2029792 URI
024a https://doi.org/10.1016/j.ijmm.2013.01.0052 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Ellström, Patriku Uppsala universitet,Klinisk bakteriologi4 aut0 (Swepub:uu)patel687
2451 0a Characterization of clinical Campylobacter jejuni isolates with special emphasis on lipooligosaccharide locus class, putative virulence factors and host response
264 1b Elsevier BV,c 2013
338 a print2 rdacarrier
520 a Recent studies have indicated a role of the lipooligosaccharide (LOS) of Campylobacter jejuni in the severe neurological Guillain Barre syndrome, as well as in development of more severe symptoms of acute enteritis. We evaluated the role of the LOS locus class in C jejuni infection among 163 enteritis patients. The prevalence of LOS locus classes differed according to the origin of the isolates. Furthermore, LOS locus classes A and B were significantly associated with susceptibility or resistance to ciprofloxacin and doxycycline. However, our results do not corroborate earlier findings that isolates with potential to sialylate LOS might be associated with more severe symptoms of enteritis. Instead, in an infection model, such isolates gave weaker epithelial IL-8 responses than nonsialylated isolates. Absence of the iron transport protein encoded by the gene ceuE as well as the putative fucose permease gene cj0486 was associated with increased in vitro IL-8 secretion. 
653 a Campylobacter
653 a Clinical isolates
653 a Patient data
653 a Lipooligosaccharide
653 a Sialic acid
653 a Host response
700a Feodoroff, Benjamin4 aut
700a Hanninen, Marja-Liisa4 aut
700a Rautelin, Hilpiu Uppsala universitet,Klinisk bakteriologi4 aut0 (Swepub:uu)hilra999
710a Uppsala universitetb Klinisk bakteriologi4 org
773t International Journal of Medical Microbiologyd : Elsevier BVg 303:3, s. 134-139q 303:3<134-139x 1438-4221x 1618-0607
856u https://doi.org/10.1016/j.ijmm.2013.01.005
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-202979
8564 8u https://doi.org/10.1016/j.ijmm.2013.01.005

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