Sökning: WFRF:(Viallon J.) >
Diet and BMI Correl...
Diet and BMI Correlate with Metabolite Patterns Associated with Aggressive Prostate Cancer
-
- Grenville, Z. S. (författare)
- Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom
-
- Noor, U. (författare)
- Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom
-
- His, M. (författare)
- Nutrition and Metabolism Branch, International Agency for Research on Cancer, World Health Organization, Lyon, France
-
visa fler...
-
- Viallon, V. (författare)
- Nutrition and Metabolism Branch, International Agency for Research on Cancer, World Health Organization, Lyon, France
-
- Rinaldi, S. (författare)
- Nutrition and Metabolism Branch, International Agency for Research on Cancer, World Health Organization, Lyon, France
-
- Aglago, E. K. (författare)
- Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom
-
- Amiano, P. (författare)
- Ministry of Health of the Basque Government, Sub Directorate for Public Health and Addictions of Gipuzkoa, San Sebastian, Spain; Biodonostia Health Research Institute, Epidemiology of Chronic and Communicable Diseases Group, 20014 San Sebastián, Spain; Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain,CIBER Epidemiology and Public Health (CIBERESP)
-
- Brunkwall, Louise (författare)
- Lund University,Lunds universitet,Diabetes - kardiovaskulär sjukdom,Forskargrupper vid Lunds universitet,Diabetes - Cardiovascular Disease,Lund University Research Groups
-
- Chirlaque, M. D. (författare)
- CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain; Department of Epidemiology, Regional Health Council, IMIB-Arrixaca, Murcia University, Murcia, Spain
-
- Drake, Isabel (författare)
- Lund University,Lunds universitet,Diabetes - kardiovaskulär sjukdom,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Diabetes - Cardiovascular Disease,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Skåne University Hospital
-
- Eichelmann, F. (författare)
- Department of Molecular Epidemiology, German Institute of Human Nutrition, Nuthetal, Germany
-
- Freisling, H. (författare)
- Nutrition and Metabolism Branch, International Agency for Research on Cancer, World Health Organization, Lyon, France
-
- Grioni, S. (författare)
- Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
-
- Heath, A. K. (författare)
- Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom
-
- Kaaks, R. (författare)
- Department of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany
-
- Katzke, V. (författare)
- Department of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany
-
- Mayen-Chacon, A. L. (författare)
- Nutrition and Metabolism Branch, International Agency for Research on Cancer, World Health Organization, Lyon, France
-
- Milani, L. (författare)
- Cancer Epidemiology Unit, Department of Medical Sciences, University of Turin, Turin, Italy
-
- Moreno-Iribas, C. (författare)
- CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain; Navarra Public Health Institute, Pamplona, Spain; Navarra Institute for Health Research (IdiSNA), Pamplona, Spain
-
- Pala, V. (författare)
- Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
-
- Olsen, A. (författare)
- Danish Cancer Society Research Center, Copenhagen, Denmark; Department of Public Health, Aarhus University, Denmark
-
- Sanchez, M. J. (författare)
- Escuela Andaluza de Salud Pública (EASP), Granada, Spain; Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain; Department of Preventive Medicine and Public Health, University of Granada, Granada, Spain,CIBER Epidemiology and Public Health (CIBERESP),Andalusian School Of Public Health (EASP)
-
- Schulze, M. B. (författare)
- Department of Molecular Epidemiology, German Institute of Human Nutrition, Nuthetal, Germany
-
- Tjonneland, A. (författare)
- Danish Cancer Society Research Center, Copenhagen, Denmark; Department of Public Health, University of Copenhagen, Copenhagen, Denmark
-
- Tsilidis, K. K. (författare)
- Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom; Department of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, Greece
-
- Weiderpass, E. (författare)
- International Agency for Research on Cancer, World Health Organization, Lyon, France
-
- Winkvist, Anna, 1962 (författare)
- Umeå University,Umeå universitet,Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition,Avdelningen för hållbar hälsa,Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
-
- Zamora-Ros, R. (författare)
- Unit of Nutrition and Cancer, Cancer Epidemiology Research Programme, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain
-
- Key, T. J. (författare)
- Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom
-
- Smith-Byrne, K. (författare)
- Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom
-
- Travis, R. C. (författare)
- Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom
-
- Schmidt, J. A. (författare)
- Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom; Department of Clinical Epidemiology, Department of Clinical Medicine, University Hospital, Aarhus University and Aarhus, DK-8200 Aarhus N, Denmark
-
visa färre...
-
(creator_code:org_t)
- 2022-08-12
- 2022
- Engelska.
-
Ingår i: Nutrients. - : MDPI AG. - 2072-6643. ; 14:16
- Relaterad länk:
-
https://doi.org/10.3...
-
visa fler...
-
https://umu.diva-por... (primary) (Raw object)
-
http://dx.doi.org/10... (free)
-
https://gup.ub.gu.se...
-
https://doi.org/10.3...
-
https://urn.kb.se/re...
-
https://lup.lub.lu.s...
-
visa färre...
Abstract
Ämnesord
Stäng
- Three metabolite patterns have previously shown prospective inverse associations with the risk of aggressive prostate cancer within the European Prospective Investigation into Cancer and Nutrition (EPIC). Here, we investigated dietary and lifestyle correlates of these three prostate cancer-related metabolite patterns, which included: 64 phosphatidylcholines and three hydroxysphingomyelins (Pattern 1), acylcarnitines C18:1 and C18:2, glutamate, ornithine, and taurine (Pattern 2), and 8 lysophosphatidylcholines (Pattern 3). In a two-stage cross-sectional discovery (n = 2524) and validation (n = 518) design containing 3042 men free of cancer in EPIC, we estimated the associations of 24 dietary and lifestyle variables with each pattern and the contributing individual metabolites. Associations statistically significant after both correction for multiple testing (False Discovery Rate = 0.05) in the discovery set and at p < 0.05 in the validation set were considered robust. Intakes of alcohol, total fish products, and its subsets total fish and lean fish were positively associated with Pattern 1. Body mass index (BMI) was positively associated with Pattern 2, which appeared to be driven by a strong positive BMI-glutamate association. Finally, both BMI and fatty fish were inversely associated with Pattern 3. In conclusion, these results indicate associations of fish and its subtypes, alcohol, and BMI with metabolite patterns that are inversely associated with risk of aggressive prostate cancer.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Näringslära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- metabolites
- diet
- prostate cancer
- cross-sectional
- body-mass index
- differentiated thyroid-carcinoma
- alcohol-consumption
- targeted metabolomics
- fatty-acids
- fish-oil
- risk
- products
- validity
- cohort
- Nutrition & Dietetics
- cross-sectional
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Grenville, Z. S.
-
Noor, U.
-
His, M.
-
Viallon, V.
-
Rinaldi, S.
-
Aglago, E. K.
-
visa fler...
-
Amiano, P.
-
Brunkwall, Louis ...
-
Chirlaque, M. D.
-
Drake, Isabel
-
Eichelmann, F.
-
Freisling, H.
-
Grioni, S.
-
Heath, A. K.
-
Kaaks, R.
-
Katzke, V.
-
Mayen-Chacon, A. ...
-
Milani, L.
-
Moreno-Iribas, C ...
-
Pala, V.
-
Olsen, A.
-
Sanchez, M. J.
-
Schulze, M. B.
-
Tjonneland, A.
-
Tsilidis, K. K.
-
Weiderpass, E.
-
Winkvist, Anna, ...
-
Zamora-Ros, R.
-
Key, T. J.
-
Smith-Byrne, K.
-
Travis, R. C.
-
Schmidt, J. A.
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Hälsovetenskap
-
och Näringslära
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Cancer och onkol ...
- Artiklar i publikationen
-
Nutrients
- Av lärosätet
-
Göteborgs universitet
-
Umeå universitet
-
Lunds universitet