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Effects of divalent metal ions on the uptake of glutamate and GABA from synaptosomal fractions
- Gabrielsson, Britt, 1957 (author)
- Robson, T (author)
- Norris, D (author)
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- Chung, Shin-Ho (author)
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- 1986
- 1986
- English.
- In: Brain Research. - 0006-8993. ; 384:2, s. 218-23
- Journal article (peer-reviewed)
Abstract
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- The effects of divalent metal ions on high affinity uptake glutamate and GABA were examined, using crude and purified synaptosomal fractions prepared from brains of DBA/2CBI. The uptake velocities of both amino acids are severely reduced in the presence of Cu2+, Fe2+ and Zn2+ but remain unaffected by Co2+.
Subject headings
- NATURVETENSKAP -- Biologi -- Biokemi och molekylärbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Biochemistry and Molecular Biology (hsv//eng)
- NATURVETENSKAP -- Kemi -- Analytisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Analytical Chemistry (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
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- Chalmers University of Technology
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