Search: hsv:(NATURVETENSKAP) hsv:(Biologi) hsv:(Biokemi och molekylärbiologi) >
A key malaria metab...
A key malaria metabolite modulates vector blood seeking, feeding, and susceptibility to infection
-
- Emami, S. Noushin (author)
- Stockholms universitet,Institutionen för molekylär biovetenskap, Wenner-Grens institut,Swedish University of Agricultural Sciences, Sweden
-
- Lindberg, Bo G. (author)
- Stockholms universitet,Institutionen för molekylär biovetenskap, Wenner-Grens institut
-
- Hua, Susanna (author)
- Stockholms universitet,Institutionen för molekylär biovetenskap, Wenner-Grens institut
-
show more...
-
- Hill, Sharon (author)
- Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Växtskyddsbiologi,Department of Plant Protection Biology
-
- Mozuraitis, Raimondas (author)
- KTH,Organisk kemi
-
- Lehmann, Philipp (author)
- Stockholms universitet,Zoologiska institutionen
-
- Birgersson, Göran (author)
- Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Växtskyddsbiologi,Department of Plant Protection Biology
-
- Borg Karlsson, Anna Karin (author)
- KTH,Organisk kemi
-
- Ignell, Rickard (author)
- Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Växtskyddsbiologi,Department of Plant Protection Biology
-
- Faye, Ingrid (author)
- Stockholms universitet,Institutionen för molekylär biovetenskap, Wenner-Grens institut
-
show less...
-
(creator_code:org_t)
-
- American Association for the Advancement of Science (AAAS), 2017
- 2017
- English.
-
In: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 355:6329
- Related links:
-
https://urn.kb.se/re...
-
show more...
-
https://doi.org/10.1...
-
https://res.slu.se/i...
-
https://urn.kb.se/re...
-
show less...
Abstract
Subject headings
Close
- Malaria infection renders humans more attractive to Anopheles gambiae sensu lato mosquitoes than uninfected people. The mechanisms remain unknown. We found that an isoprenoid precursor produced by Plasmodium falciparum, (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate (HMBPP), affects A. gambiae s. l. blood meal seeking and feeding behaviors as well as susceptibility to infection. HMBPP acts indirectly by triggering human red blood cells to increase the release of CO2, aldehydes, and monoterpenes, which together enhance vector attraction and stimulate vector feeding. When offered in a blood meal, HMBPP modulates neural, antimalarial, and oogenic gene transcription without affecting mosquito survival or fecundity; in a P. falciparum-infected blood meal, sporogony is increased.
Subject headings
- NATURVETENSKAP -- Biologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Mikrobiologi inom det medicinska området (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Microbiology in the medical area (hsv//eng)
- NATURVETENSKAP -- Biologi -- Ekologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Ecology (hsv//eng)
- NATURVETENSKAP -- Biologi -- Biokemi och molekylärbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Biochemistry and Molecular Biology (hsv//eng)
- NATURVETENSKAP -- Biologi -- Etologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Behavioural Sciences Biology (hsv//eng)
- NATURVETENSKAP -- Kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
-
Science
(Search for host publication in LIBRIS)
To the university's database
- By the author/editor
-
Emami, S. Noushi ...
-
Lindberg, Bo G.
-
Hua, Susanna
-
Hill, Sharon
-
Mozuraitis, Raim ...
-
Lehmann, Philipp
-
show more...
-
Birgersson, Göra ...
-
Borg Karlsson, A ...
-
Ignell, Rickard
-
Faye, Ingrid
-
show less...
- About the subject
-
- NATURAL SCIENCES
-
NATURAL SCIENCES
-
and Biological Scien ...
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Basic Medicine
-
and Microbiology in ...
-
- NATURAL SCIENCES
-
NATURAL SCIENCES
-
and Biological Scien ...
-
and Ecology
-
- NATURAL SCIENCES
-
NATURAL SCIENCES
-
and Biological Scien ...
-
and Biochemistry and ...
-
- NATURAL SCIENCES
-
NATURAL SCIENCES
-
and Biological Scien ...
-
and Behavioural Scie ...
-
- NATURAL SCIENCES
-
NATURAL SCIENCES
-
and Chemical Science ...
- Articles in the publication
-
Science
- By the university
-
Stockholm University
-
Swedish University of Agricultural Sciences
-
Royal Institute of Technology