Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

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024	7	a https://lup.lub.lu.se/record/916bdc2c-1aae-4d2e-ae43-b0b6f891545c2 URI
024	7	a https://doi.org/10.1038/ng.36542 DOI
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1279532 URI
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3062512 URI
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100	1	a Surendran, Praveenu University of Cambridge,Univ Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge, England.4 aut
245	1 0	a Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension
264		c 2016-09-12
264	1	b Springer Science and Business Media LLC,c 2016
300		a 11 s.
520		a High blood pressure is a major risk factor for cardiovascular disease and premature death. However, there is limited knowledge on specific causal genes and pathways. To better understand the genetics of blood pressure, we genotyped 242,296 rare, low-frequency and common genetic variants in up to 192,763 individuals and used -1/4155,063 samples for independent replication. We identified 30 new blood pressure- or hypertension-associated genetic regions in the general population, including 3 rare missense variants in RBM47, COL21A1 and RRAS with larger effects (>1.5 mm Hg/allele) than common variants. Multiple rare nonsense and missense variant associations were found in A2ML1, and a low-frequency nonsense variant in ENPEP was identified. Our data extend the spectrum of allelic variation underlying blood pressure traits and hypertension, provide new insights into the pathophysiology of hypertension and indicate new targets for clinical intervention.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Medicinsk genetik0 (SwePub)301072 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Medical Genetics0 (SwePub)301072 hsv//eng
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
700	1	a Drenos, Fotiosu University College London,University of Bristol,Univ Bristol, Sch Social & Community Med, Med Res Council Integrat Epidemiol Unit, Oakfield House, Bristol, Avon, England.;UCL, Inst Cardiovasc Sci, Ctr Cardiovasc Genet, London, England.4 aut
700	1	a Young, Robinu University of Cambridge,Univ Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge, England.4 aut
700	1	a Warren, Helenu Queen Mary University,Queen Mary Univ London, William Harvey Res Inst, Clin Pharmacol, London, England.;Queen Mary Univ London, Natl Inst Hlth Res, Barts Cardiovasc Biomed Res Unit, London, England.4 aut
700	1	a Cook, James P.u University of Leicester,University of Liverpool,Univ Leicester, Dept Hlth Sci, Leicester, Leics, England.;Univ Liverpool, Dept Biostat, Liverpool, Merseyside, England.4 aut
700	1	a Manning, Alisa K.u Broad Institute,Harvard University,Massachusetts General Hospital,Harvard Med Sch, Dept Genet, Boston, MA USA.;Broad Inst, Program Med & Populat Genet, Cambridge, MA USA.;Massachusetts Gen Hosp, Dept Mol Biol, Boston, MA 02114 USA.,Natl Inst Hlth & Welf, Dept Hlth, Helsinki, Finland.,Finnish National Institute for Health and Welfare4 aut
700	1	a Grarup, Nielsu University of Copenhagen,Univ Copenhagen, Fac Hlth & Med Sci, Novo Nordisk Fdn Ctr Basic Metab Res, Copenhagen, Denmark.4 aut
700	1	a Sim, Xuelingu National University of Singapore,University of Michigan,Univ Michigan, Ctr Stat Genet, Ann Arbor, MI 48109 USA.;Univ Michigan, Dept Biostat, Ann Arbor, MI USA.;Natl Univ Singapore, Natl Univ Hlth Syst, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore.4 aut
700	1	a Barnes, Daniel R.u University of Cambridge,Univ Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge, England.,Kuopio Res Inst Exercise Med, Kuopio, Finland.;Kuopio Univ Hosp, Dept Clin Physiol & Nucl Med, Kuopio, Finland.,Kuopio University Hospital4 aut
700	1	a Witkowska, Kateu Queen Mary University,Queen Mary Univ London, William Harvey Res Inst, Clin Pharmacol, London, England.;Queen Mary Univ London, Natl Inst Hlth Res, Barts Cardiovasc Biomed Res Unit, London, England.4 aut
700	1	a Staley, James R.u University of Cambridge,Univ Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge, England.4 aut
700	1	a Tragante, Viniciusu University Medical Center Utrecht,Univ Med Ctr Utrecht, Dept Cardiol, Utrecht, Netherlands.4 aut
700	1	a Tukiainen, Taruu Broad Institute,Harvard University,Massachusetts General Hospital,Harvard Med Sch, Dept Genet, Boston, MA USA.;Broad Inst, Program Med & Populat Genet, Cambridge, MA USA.;Massachusetts Gen Hosp, Dept Med, Analyt & Translat Genet Unit, Boston, MA 02114 USA.,Washington Univ, Ctr Genome Sci & Syst Biol, Div Stat Genom, Sch Med, St Louis, MO USA.;Washington Univ, Dept Genet, Sch Med, St Louis, MO USA.,Washington University in St. Louis4 aut
700	1	a Yaghootkar, Haniehu University of Exeter,Univ Exeter, Inst Biomed & Clin Sci, Genet Complex Traits, Sch Med, Exeter, Devon, England.4 aut
700	1	a Masca, Nicholasu National Institute for Health Research, United Kingdom,University of Leicester,Univ Leicester, Dept Cardiovasc Sci, Leicester, Leics, England.;Natl Inst Hlth, Res Leicester Biomed Res Unit Cardiovasc Dis, Leicester, Leics, England.4 aut
700	1	a Freitag, Daniel F.u University of Cambridge,Univ Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge, England.4 aut
700	1	a Ferreira, Teresau University of Oxford,Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, Oxford, England.4 aut
700	1	a Giannakopoulou, Olgau Queen Mary University,Queen Mary Univ London, William Harvey Res Inst, Bads & London Sch Med & Dent, Ctr Heart, London, England.4 aut
700	1	a Tinker, Andrewu Queen Mary University,Queen Mary Univ London, Natl Inst Hlth Res, Barts Cardiovasc Biomed Res Unit, London, England.;Queen Mary Univ London, William Harvey Res Inst, Bads & London Sch Med & Dent, Ctr Heart, London, England.4 aut
700	1	a Harakalova, Magdalenau University Medical Center Utrecht,Univ Med Ctr Utrecht, Dept Cardiol, Utrecht, Netherlands.4 aut
700	1	a Mihailov, Evelinu University of Tartu,Univ Tartu, Estonian Genome Ctr, Tartu, Estonia.4 aut
700	1	a Liu, Chunyuu National Heart Lung and Blood Institute,Boston University,NHLBI, Framingham, MA USA.;Boston Univ, Framingham Heart Study, Framingham, MA USA.4 aut
700	1	a Tuomi, Tiinamaijau Washington University in St. Louis,Folkhalsan Res Ctr, Helsinki, Finland.;Univ Helsinki, Dept Endocrinol, Cent Hosp, Helsinki, Finland.;Univ Helsinki, Inst Mol Med Finland, Helsinki, Finland.,Helsinki University Central Hospital,University of Helsinki,Folkhälsan Research Center4 aut0 (Swepub:lu)ti8736tu
700	1	a Nielsen, Sune Fallgaardu Copenhagen University Hospital,Copenhagen Univ Hosp, Dept Clin Biochem, Herlev Hosp, Herlev, Denmark.4 aut
700	1	a Rasheed, Asifu Centre for Non-Communicable Diseases,Ctr Noncommunicable Dis, Karachi, Pakistan.4 aut
700	1	a Samuel, Mariau Centre for Non-Communicable Diseases,Ctr Noncommunicable Dis, Karachi, Pakistan.4 aut
700	1	a Zhao, Weiu University of Pennsylvania,Univ Penn, Dept Biostat & Epidemiol, Perelman Sch Med, Philadelphia, PA 19104 USA.4 aut
700	1	a Lannfelt, Larsu Uppsala University,Uppsala universitet,Geriatrik,Capital Reg Denmark, Res Ctr Prevent & Hlth, Copenhagen, Denmark.,Univ N Carolina, Dept Genet, Chapel Hill, NC USA.,National Human Genome Research Institute,Research Centre for Prevention and Health,University of North Carolina4 aut0 (Swepub:uu)lalan021
700	1	a Jackson, Anne U.u University of Michigan,Univ Michigan, Ctr Stat Genet, Ann Arbor, MI 48109 USA.;Univ Michigan, Dept Biostat, Ann Arbor, MI USA.4 aut
700	1	a Narisu, Narisuu National Human Genome Research Institute,NHGRI, Med Genom & Metab Genet Branch, US Natl Inst Hlth, Bethesda, MD 20892 USA.,Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, Oxford, England.;Wellcome Trust Sanger Inst, Genome Campus, Hinxton, England.;Univ Oxford, Radcliffe Dept Med, Ctr Diabet, Endocrinol & Metab, Oxford, England.,Univ Dundee, Med Res Inst, Ninewells Hosp & Med Sch, Dundee, Scotland.,University of Oxford,University of Dundee4 aut
700	1	a Swift, Amy J.u National Human Genome Research Institute,NHGRI, Med Genom & Metab Genet Branch, US Natl Inst Hlth, Bethesda, MD 20892 USA.4 aut
700	1	a Southam, Lorraineu Wellcome Trust Sanger Institute,Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, Oxford, England.;Wellcome Trust Sanger Inst, Genome Campus, Hinxton, England.4 aut
700	1	a Marten, Jonathanu University of Edinburgh,Univ Edinburgh, Med Res Council Human Genet Unit, Med Res Council Inst Genet & Mol Med, Edinburgh, Midlothian, Scotland.,Leiden Univ, Dept Gerontol & Geriatr, Med Ctr, Leiden, Netherlands.,Leiden University Medical Centre4 aut
700	1	a Huyghe, Jeroen R.u University of Michigan,Univ Michigan, Ctr Stat Genet, Ann Arbor, MI 48109 USA.;Univ Michigan, Dept Biostat, Ann Arbor, MI USA.4 aut
700	1	a Stančáková, Alenau University of Eastern Finland,Univ Eastern Finland, Dept Med, Kuopio, Finland.;Kuopio Univ Hosp, Kuopio, Finland.4 aut
700	1	a Fava, Cristianou Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups,University of Verona,Lund Univ, Dept Clin Sci, Malmo, Sweden.;Univ Verona, Dept Med, Verona, Italy.4 aut0 (Swepub:lu)endo-cfa
700	1	a Ohlsson, Thereseu Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups,Lund Univ, Dept Clin Sci, Malmo, Sweden.4 aut0 (Swepub:lu)med-ton
700	1	a Matchan, Angelau Wellcome Trust Sanger Institute,Wellcome Trust Sanger Inst, Genome Campus, Hinxton, England.4 aut
700	1	a Stirrups, Kathleen E.u University of Cambridge,Queen Mary Univ London, William Harvey Res Inst, Bads & London Sch Med & Dent, Ctr Heart, London, England.;Univ Cambridge, Dept Haematol, Cambridge, England.,Imperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, London, England.;Univ Ioannina, Dept Hyg & Epidemiol, Sch Med, Ioannina, Greece.,University of Ioannina4 aut
700	1	a Bork-Jensen, Jetteu University of Copenhagen,Univ Copenhagen, Fac Hlth & Med Sci, Novo Nordisk Fdn Ctr Basic Metab Res, Copenhagen, Denmark.4 aut
700	1	a Gjesing, Anette P.u University of Copenhagen,Univ Copenhagen, Fac Hlth & Med Sci, Novo Nordisk Fdn Ctr Basic Metab Res, Copenhagen, Denmark.4 aut
700	1	a Kontto, Jukkau Finnish National Institute for Health and Welfare,Natl Inst Hlth & Welf, Dept Hlth, Helsinki, Finland.4 aut
700	1	a Perola, Markusu Finnish National Institute for Health and Welfare,University of Helsinki,University of Tartu,Univ Tartu, Estonian Genome Ctr, Tartu, Estonia.;Natl Inst Hlth & Welf, Dept Hlth, Helsinki, Finland.;Univ Helsinki, Inst Mol Med FIMM, Helsinki, Finland.4 aut0 (Swepub:lu)med-mkp
700	1	a Shaw-Hawkins, Susanu Queen Mary University,Queen Mary Univ London, William Harvey Res Inst, Clin Pharmacol, London, England.4 aut
700	1	a Havulinna, Aki S.u Finnish National Institute for Health and Welfare,Natl Inst Hlth & Welf, Dept Hlth, Helsinki, Finland.4 aut
700	1	a Zhang, Heu University of Michigan,Univ Michigan, Dept Internal Med, Div Cardiovasc Med, Ann Arbor, MI 48109 USA.4 aut
700	1	a Donnelly, Louise A.u University of Dundee,Univ Dundee, Med Res Inst, Ninewells Hosp & Med Sch, Dundee, Scotland.4 aut
700	1	a Groves, Christopher J.u University of Oxford,Univ Oxford, Radcliffe Dept Med, Ctr Diabet, Endocrinol & Metab, Oxford, England.4 aut
700	1	a Rayner, N. Williamu University of Oxford4 aut
700	1	a Neville, Matt J.u University of Oxford,Univ Oxford, Radcliffe Dept Med, Ctr Diabet, Endocrinol & Metab, Oxford, England.;Oxford Univ Hosp Trusts, Natl Inst Hlth, Res Oxford Biomed Res Ctr, Oxford, England.4 aut
700	1	a Robertson, Neil R.u University of Oxford,Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, Oxford, England.;Univ Oxford, Radcliffe Dept Med, Ctr Diabet, Endocrinol & Metab, Oxford, England.4 aut
700	1	a Yiorkas, Andrianos M.u Brunel University London,Imperial Coll London, Sect Invest Med, London, England.;Brunel Univ London, Dept Life Sci, London, England.4 aut
700	1	a Herzig, Karl Heinzu Poznan University of Medical Sciences,Univ Oulu, Inst Biomed, Bioctr Oulu, Oulu, Finland.;Poznan Univ Med Sci, Dept Gastroenterol & Metab, Poznan, Poland.4 aut
700	1	a Kajantie, Eerou Finnish National Institute for Health and Welfare,University of Helsinki,University of Oulu,Natl Inst Hlth & Welf, Dept Hlth, Helsinki, Finland.;Univ Helsinki, Cent Hosp, Hosp Children & Adolescents, Helsinki, Finland.;Univ Helsinki, Helsinki, Finland.;Oulu Univ Hosp, Dept Obstet & Gynaecol, Oulu, Finland.;Univ Oulu, Oulu, Finland.4 aut
700	1	a Zhang, Weihuau Imperial College London,Ealing Hospital,Imperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, London, England.;Ealing Gen Hosp, Dept Cardiol, Middlesex, Middx, England.4 aut
700	1	a Willems, Sara M.u University of Cambridge,Univ Cambridge, Sch Clin Med, Med Res Council Epidemiol Unit, Inst Metab Sci, Cambridge Biomed Campus, Cambridge, England.4 aut
700	1	a Lannfelt, Larsu Uppsala University4 aut
700	1	a Malerba, Giovanniu University of Verona,Univ Verona, Dept Neurosci Biomed & Movement Sci, Sect Biol & Genet, Verona, Italy.4 aut
700	1	a Soranzo, Nicoleu University of Cambridge,Univ Cambridge, Dept Haematol, Cambridge, England.;Wellcome Trust Sanger Inst, Human Genet, Hinxton, England.;Univ Cambridge, NIHR Blbod & Transplant Res Unit Donor Hlth & Gen, Cambridge, England.4 aut
700	1	a Trabetti, Elisabettau University of Verona,Univ Verona, Dept Neurosci Biomed & Movement Sci, Sect Biol & Genet, Verona, Italy.4 aut
700	1	a Verweij, Nieku Massachusetts General Hospital,Broad Inst, Program Med & Populat Genet, Cambridge, MA USA.;Univ Groningen, Univ Med Ctr Groningen, Dept Cardiol, Groningen, Netherlands.;Massachusetts Gen Hosp, Ctr Human Genet Res, Boston, MA 02114 USA.4 aut
700	1	a Evangelou, Evangelosu University of Ioannina,Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Edinburgh, Midlothian, Scotland.;Univ Edinburgh, Med Res Council Inst Genet & Mol Med, Ctr Genom & Expt Med, Edinburgh, Midlothian, Scotland.,NHLBI, Framingham, MA USA.;Boston Univ, Framingham Heart Study, Framingham, MA USA.;Univ Edinburgh, Med Res Council Human Genet Unit, Med Res Council Inst Genet & Mol Med, Edinburgh, Midlothian, Scotland.,Univ N Carolina, Dept Epidemiol, Chapel Hill, NC USA.,Univ Med Ctr Utrecht, Dept Epidemiol, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands.;Leiden Univ, Dept Publ Hlth & Primary Care, Med Ctr, Leiden, Netherlands.;Imperial Coll Healthcare NHS Trust, London, England.,University of Edinburgh,University of North Carolina,Leiden University Medical Centre4 aut
700	1	a Moayyeri, Alirezau Imperial College London,University College London,Imperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, London, England.;UCL, Farr Inst Hlth Informat Res, Inst Hlth Informat, London, England.4 aut
700	1	a Vergnaud, Anne Claireu Imperial College London,Imperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, London, England.4 aut
700	1	a Nelson, Christopher P.u National Institute for Health Research, United Kingdom,Univ Leicester, Dept Cardiovasc Sci, Leicester, Leics, England.;Natl Inst Hlth, Res Leicester Biomed Res Unit Cardiovasc Dis, Leicester, Leics, England.4 aut
700	1	a Poveda, Alaitzu Lund University,Lunds universitet,Translationell muskelforskning,Forskargrupper vid Lunds universitet,Translational Muscle Research,Lund University Research Groups,University of the Basque Country,Lund Univ, Genet & Mol Epidemiol Unit, Dept Clin Sci, Malmo, Sweden.;Univ Basque Country UPV EHU, Fac Sci & Technol, Dept Genet Phys Anthropol & Anim Physiol, Bilbao, Spain.4 aut0 (Swepub:lu)med-azp
700	1	a Varga, Tibor V.u Lund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups,Lund Univ, Genet & Mol Epidemiol Unit, Dept Clin Sci, Malmo, Sweden.4 aut0 (Swepub:lu)med-tv_
700	1	a Caslake, Murielu University of Glasgow,Univ Glasgow, Cardiovasc & Med Sci, Glasgow, Lanark, Scotland.,Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Edinburgh, Midlothian, Scotland.;Univ Edinburgh, Dept Psychol, Edinburgh, Midlothian, Scotland.,University of Edinburgh4 aut
700	1	a De Craen, Anton J Mu Leiden University Medical Centre4 aut
700	1	a Trompet, Stellau Leiden University Medical Centre,Leiden Univ, Dept Gerontol & Geriatr, Med Ctr, Leiden, Netherlands.;Leiden Univ, Med Ctr, Dept Cardiol, Leiden, Netherlands.4 aut
700	1	a Luan, Jian'Anu University of Cambridge,Univ Cambridge, Sch Clin Med, Med Res Council Epidemiol Unit, Inst Metab Sci, Cambridge Biomed Campus, Cambridge, England.4 aut
700	1	a Scott, Robert A.u University of Cambridge,Univ Cambridge, Sch Clin Med, Med Res Council Epidemiol Unit, Inst Metab Sci, Cambridge Biomed Campus, Cambridge, England.4 aut
700	1	a Harris, Sarah E.u University of Edinburgh4 aut
700	1	a Liewald, David C Mu University of Edinburgh,Kings Coll London, Dept Twin Res & Genet Epidemiol, London, England.,Lillebaelt Hosp, Dept Med, Vejle, Denmark.,King's College London,Lillebaelt Hospital4 aut
700	1	a Marioni, Riccardou University of Queensland,Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Edinburgh, Midlothian, Scotland.;Univ Edinburgh, Med Res Council Inst Genet & Mol Med, Ctr Genom & Expt Med, Edinburgh, Midlothian, Scotland.;Univ Queensland, Queensland Brain Inst, Brisbane, Qld, Australia.4 aut
700	1	a Menni, Cristinau King's College London4 aut
700	1	a Farmaki, Aliki Eleniu Harokopio University,Harokopio Univ, Sch Hlth Sci & Educ, Dept Nutr & Dietet, Athens, Greece.4 aut
700	1	a Hallmans, Göranu Umeå universitet,Umeå University,Enheten för biobanksforskning,Umea Univ, Dept Biobank Res, Umea, Sweden.4 aut0 (Swepub:umu)goha0001
700	1	a Renström, Fridau Umeå universitet,Umeå University,Lund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups,Enheten för biobanksforskning,Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmö, Sweden,Lund Univ, Genet & Mol Epidemiol Unit, Dept Clin Sci, Malmo, Sweden.;Umea Univ, Dept Biobank Res, Umea, Sweden.4 aut0 (Swepub:umu)frre0001
700	1	a Huffman, Jennifer E.u University of Edinburgh4 aut
700	1	a Hassinen, Maijau University of Eastern Finland,Kuopio Res Inst Exercise Med, Kuopio, Finland.4 aut
700	1	a Burgess, Stephenu University of Cambridge,Univ Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge, England.4 aut
700	1	a Vasan, Ramachandran S.u Boston University,NHLBI, Framingham, MA USA.;Boston Univ, Framingham Heart Study, Framingham, MA USA.;Boston Univ, Dept Med, Sect Cardiol, Sch Med, Boston, MA USA.;Boston Univ, Sch Publ Hlth, Boston, MA USA.;Boston Univ, Dept Med, Sect Prevent Med, Sch Med, Boston, MA USA.;Boston Univ, Dept Med, Sect Epidemiol, Sch Med, Boston, MA USA.;Boston Univ, Sch Publ Hlth, Boston, MA USA.4 aut
700	1	a Felix, Janine F.u Erasmus University Medical Center,Erasmus MC, Univ Med Ctr Rotterdam, Dept Epidemiol, Rotterdam, Netherlands.4 aut
700	1	a Uria-Nickelsen, Mariau Pfizer Inc. US,Pfizer Worldwide Res & Dev, Dev Management & Planning, Cambridge, MA USA.4 aut
700	1	a Malarstig, Andersu Pfizer Inc. US,Pfizer Worldwide Res & Dev, Stockholm, Sweden.4 aut
700	1	a Reilly, Dermot F.u Merck Research Laboratories,Merck Res Labs, Genet & Pharmacogen, Boston, MA USA.4 aut
700	1	a Hoek, Maartenu Merck Research Laboratories,Merck Res Labs, Cardiometab Dis, Kenilworth, NJ USA.4 aut
700	1	a Vogt, Thomas F.u Merck Research Laboratories,Merck Res Labs, Cardiometab Dis, Kenilworth, NJ USA.;CHDI Management CHDI Fdn, Princeton, NJ USA.4 aut
700	1	a Lin, Honghuangu Boston University,NHLBI, Framingham, MA USA.;Boston Univ, Framingham Heart Study, Framingham, MA USA.;Boston Univ, Sch Med, Dept Med, Sect Computat Biomed, Boston, MA 02215 USA.4 aut
700	1	a Lieb, Wolfgangu University of Kiel,Univ Kiel, Inst Epidemiol & Biobank Popgen, Kiel, Germany.4 aut
700	1	a Traylor, Matthewu University of Cambridge,Univ Cambridge, Neurol Unit, Cambridge Biomed Campus, Cambridge, England.4 aut
700	1	a Markus, Hugh S.u University of Cambridge,Univ Cambridge, Neurol Unit, Cambridge Biomed Campus, Cambridge, England.4 aut
700	1	a Highland, Heather M.u University of North Carolina,Univ N Carolina, Dept Epidemiol, Chapel Hill, NC USA.4 aut
700	1	a Justice, Anne E.u University of North Carolina4 aut
700	1	a Marouli, Eiriniu Queen Mary University,Queen Mary Univ London, William Harvey Res Inst, Bads & London Sch Med & Dent, Ctr Heart, London, England.4 aut
700	1	a Lindström, Jaanau Finnish National Institute for Health and Welfare,Natl Inst Hlth & Welf, Dept Hlth, Helsinki, Finland.4 aut
700	1	a Uusitupa, Mattiu Kuopio University Hospital,Univ Eastern Finland, Dept Publ Hlth & Clin Nutr, Kuopio, Finland.;Kuopio Univ Hosp, Res Unit, Kuopio, Finland.4 aut
700	1	a Komulainen, Pirjou University of Eastern Finland,Kuopio Res Inst Exercise Med, Kuopio, Finland.4 aut
700	1	a Lakka, Timo A.u Kuopio University Hospital,Kuopio Res Inst Exercise Med, Kuopio, Finland.;Univ Eastern Finland, Inst Biomed Physiol, Kuopio Campus, Kuopio, Finland.;Kuopio Univ Hosp, Dept Clin Physiol & Nucl Med, Kuopio, Finland.4 aut
700	1	a Rauramaa, Raineru Kuopio University Hospital,Lillebaelt Hosp, Dept Clin Immunol & Biochem, Vejle, Denmark.,Lillebaelt Hospital4 aut
700	1	a Polasek, Ozrenu University of Split,Univ Edinburgh, Usher Inst Populat Hlth Sci & Informat, Ctr Global Hlth Res, Edinburgh, Midlothian, Scotland.;Univ Split, Fac Med, Split, Croatia.4 aut
700	1	a Rudan, Igoru University of Edinburgh,Univ Edinburgh, Usher Inst Populat Hlth Sci & Informat, Ctr Global Hlth Res, Edinburgh, Midlothian, Scotland.4 aut
700	1	a Rolandsson, Olovu Umeå universitet,Umeå University,Allmänmedicin,Umea Univ, Dept Publ Hlth & Clin Med, Umea, Sweden.4 aut0 (Swepub:umu)olro0005
700	1	a Franks, Paul W.u Umeå universitet,Umeå University,Lund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups,Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmö, Sweden; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA,Medicin,Lund Univ, Genet & Mol Epidemiol Unit, Dept Clin Sci, Malmo, Sweden.;Umea Univ, Dept Publ Hlth & Clin Med, Umea, Sweden.;Harvard Sch Publ Hlth, Dept Nutr, Boston, MA USA.4 aut0 (Swepub:umu)pafr0003
700	1	a Dedoussis, Georgeu Harokopio University,Harokopio Univ, Sch Hlth Sci & Educ, Dept Nutr & Dietet, Athens, Greece.4 aut
700	1	a Spector, Timothy D.u King's College London,Kings Coll London, Dept Twin Res & Genet Epidemiol, London, England.4 aut
700	1	a Jousilahti, Pekkau Finnish National Institute for Health and Welfare,Natl Inst Hlth & Welf, Dept Hlth, Helsinki, Finland.4 aut
700	1	a Männistö, Satuu Finnish National Institute for Health and Welfare,Natl Inst Hlth & Welf, Dept Hlth, Helsinki, Finland.4 aut
700	1	a Deary, Ian J.u University of Edinburgh,Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Edinburgh, Midlothian, Scotland.;Univ Edinburgh, Dept Psychol, Edinburgh, Midlothian, Scotland.4 aut
700	1	a Starr, John M.u University of Edinburgh,Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Edinburgh, Midlothian, Scotland.;Univ Edinburgh, Alzheimer Scotland Dementia Res Ctr, Edinburgh, Midlothian, Scotland.4 aut
700	1	a Langenberg, Claudiau University of Cambridge,Univ Cambridge, Sch Clin Med, Med Res Council Epidemiol Unit, Inst Metab Sci, Cambridge Biomed Campus, Cambridge, England.4 aut
700	1	a Wareham, Nick J.u University of Cambridge,Univ Cambridge, Sch Clin Med, Med Res Council Epidemiol Unit, Inst Metab Sci, Cambridge Biomed Campus, Cambridge, England.4 aut
700	1	a Brown, Morris J.u Queen Mary University,Queen Mary Univ London, William Harvey Res Inst, Clin Pharmacol, London, England.4 aut
700	1	a Dominiczak, Anna F.u University of Glasgow,Univ Glasgow, Coll Med Vet & Life Sci, Inst Cardiovasc & Med Sci, Glasgow, Lanark, Scotland.4 aut
700	1	a Connell, John M.u Ninewells Hospital and Medical School,Univ Dundee, Med Res Inst, Ninewells Hosp & Med Sch, Dundee, Scotland.4 aut
700	1	a Jukema, J. Wouteru Interuniversity Cardiology Institute of the Netherlands,Leiden Univ, Med Ctr, Dept Cardiol, Leiden, Netherlands.;Interuniv Cardiol Inst Netherlands, Utrecht, Netherlands.4 aut
700	1	a Sattar, Naveedu University of Glasgow,Univ Glasgow, Coll Med Vet & Life Sci, Inst Cardiovasc & Med Sci, Glasgow, Lanark, Scotland.4 aut
700	1	a Ford, Ianu University of Glasgow,Univ Glasgow, Cardiovasc & Med Sci, Glasgow, Lanark, Scotland.,Imperial Coll London, Sect Invest Med, London, England.;Brunel Univ London, Dept Life Sci, London, England.,Brunel University London4 aut
700	1	a Packard, Chris J.u University of Glasgow,Univ Glasgow, Cardiovasc & Med Sci, Glasgow, Lanark, Scotland.4 aut
700	1	a Esko, Tõnuu Boston Children's Hospital,Harvard Med Sch, Dept Genet, Boston, MA USA.;Broad Inst, Program Med & Populat Genet, Cambridge, MA USA.;Univ Tartu, Estonian Genome Ctr, Tartu, Estonia.;Boston Childrens Hosp, Div Endocrinol, Boston, MA USA.4 aut
700	1	a Mägi, Reediku University of Tartu,Univ Tartu, Estonian Genome Ctr, Tartu, Estonia.4 aut
700	1	a Metspalu, Andresu University of Tartu,Univ Tartu, Estonian Genome Ctr, Tartu, Estonia.;Inst Mol & Cell Biol, Tartu, Estonia.4 aut
700	1	a De Boer, Rudolf A.u University of Groningen,Univ Groningen, Univ Med Ctr Groningen, Dept Cardiol, Groningen, Netherlands.4 aut
700	1	a Van Der Meer, Peteru University of Groningen,Univ Groningen, Univ Med Ctr Groningen, Dept Cardiol, Groningen, Netherlands.,Imperial Coll London, Natl Heart & Lung Inst, London, England.,Imperial College London4 aut
700	1	a Van Der Harst, Pimu Interuniversity Cardiology Institute of the Netherlands,Univ Groningen, Univ Med Ctr Groningen, Dept Cardiol, Groningen, Netherlands.;Univ Groningen, Univ Med Ctr Groningen, Dept Genet, Groningen, Netherlands.;ICIN Netherlands Heart Inst, Durrer Ctr Cardiogenet Res, Utrecht, Netherlands.4 aut
700	1	a Gambaro, Giovanniu Catholic University of the Sacred Heart, Rome,Catholic Univ, Columbus Gemelli Univ Hosp, Dept Internal Med & Med Speciales, Div Nephrol, Rome, Italy.4 aut
700	1	a Ingelsson, Eriku Uppsala universitet,Molekylär epidemiologi,Science for Life Laboratory, SciLifeLab,Stanford Univ, Dept Med, Div Cardiovasc Med, Sch Med, Stanford, CA 94305 USA.,Stanford University4 aut0 (Swepub:uu)ering425
700	1	a Lind, Larsu Uppsala universitet,Uppsala University,Molekylär epidemiologi,Science for Life Laboratory, SciLifeLab4 aut0 (Swepub:uu)larslind
700	1	a De Bakker, Paul I Wu University Medical Center Utrecht,Univ Med Ctr Utrecht, Ctr Mol Med, Dept Med Genet, Utrecht, Netherlands.;Univ Med Ctr Utrecht, Dept Epidemiol, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands.4 aut
700	1	a Numans, Mattijs E.u Leiden University Medical Centre4 aut
700	1	a Brandslund, Ivanu University of Southern Denmark,Lillebaelt Hosp, Dept Clin Biochem, Vejle, Denmark.;Univ Southern Denmark, Inst Reg Hlth Res, Odense, Denmark.4 aut
700	1	a Christensen, Crameru Lillebaelt Hospital,Imperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, London, England.;Ealing Gen Hosp, Dept Cardiol, Middlesex, Middx, England.;Imperial Coll Healthcare NHS Trust, London, England.,National Health Service Trust, NHS England4 aut
700	1	a Petersen, Eva R Bu Lillebaelt Hospital4 aut
700	1	a Korpi-Hyövälti, Eevau South Ostrobothnia Central Hospital,South Ostrobothnia Cent Hosp, Dept Internal Med, Seinajoki, Finland.4 aut
700	1	a Oksa, Heikkiu Tampere University Hospital,Tampere Univ Hosp, Dept Internal Med, Tampere, Finland.4 aut
700	1	a Chambers, John C.u National Health Service Trust, NHS England4 aut
700	1	a Kooner, Jaspal S.u Imperial College London,Ealing Gen Hosp, Dept Cardiol, Middlesex, Middx, England.;Imperial Coll London, Natl Heart & Lung Inst, London, England.4 aut
700	1	a Blakemore, Alexandra I Fu Brunel University London4 aut
700	1	a Franks, Steveu Imperial College London,Imperial Coll London, Inst Reprod & Dev Biol, London, England.,Univ Dundee, Med Res Inst, Ninewells Hosp & Med Sch, Dundee, Scotland.,NHGRI, Med Genom & Metab Genet Branch, US Natl Inst Hlth, Bethesda, MD 20892 USA.,University of Dundee,National Human Genome Research Institute4 aut
700	1	a Jarvelin, Marjo Riittau Oulu University Hospital,Imperial Coll London, Dept Epidemiol & Biostat, Med Res Council Publ Hlth England Ctr Environm &, Sch Publ Hlth,Fac Med, St Marys Campus, London, England.;Univ Oulu, Ctr Life Course Hlth Res, Fac Med, Oulu, Finland.;Univ Oulu, Bioctr Oulu, Oulu, Finland.;Oulu Univ Hosp, Unit Primary Care, Oulu, Finland.4 aut
700	1	a Husemoen, Lise L.u Research Centre for Prevention and Health4 aut
700	1	a Linneberg, Allanu University of Copenhagen,Capital Reg Denmark, Res Ctr Prevent & Hlth, Copenhagen, Denmark.;Glostrup Univ Hosp, Dept Clin Expt Res, Glostrup, Denmark.;Univ Copenhagen, Fac Hlth & Med Sci, Dept Clin Med, Copenhagen, Denmark.4 aut
700	1	a Skaaby, Teau Research Centre for Prevention and Health,Capital Reg Denmark, Res Ctr Prevent & Hlth, Copenhagen, Denmark.4 aut
700	1	a Thuesen, Betinau Research Centre for Prevention and Health,Capital Reg Denmark, Res Ctr Prevent & Hlth, Copenhagen, Denmark.4 aut
700	1	a Karpe, Fredriku University of Oxford,Univ Oxford, Radcliffe Dept Med, Ctr Diabet, Endocrinol & Metab, Oxford, England.;Oxford Univ Hosp Trusts, Natl Inst Hlth, Res Oxford Biomed Res Ctr, Oxford, England.4 aut
700	1	a Tuomilehto, Jaakkou King Abdulaziz University,Natl Inst Hlth & Welf, Dept Hlth, Helsinki, Finland.;Dasman Diabet Inst, Kuwait, Kuwait.;Danube Univ Krems, Ctr Vasc Prevent, Krems, Austria.;King Abdulaziz Univ, Diabet Res Grp, Jeddah, Saudi Arabia.4 aut
700	1	a Doney, Alex S Fu University of Dundee4 aut
700	1	a Morris, Andrew D.u University of Edinburgh,Univ Edinburgh, Sch Med, Sch Mol Genet & Populat Hlth Sci, Teviot Pl, Edinburgh, Midlothian, Scotland.4 aut
700	1	a Palmer, Colin N Au University of Dundee4 aut
700	1	a Holmen, Oddgeir Lingaasu St. Olav’s University Hospital,Norwegian Univ Sci & Technol, Dept Publ Hlth & Gen Practice, HUNT Res Ctr, Levanger, Norway.;Univ Trondheim Hosp, St Olav Hosp, Trondheim, Norway.4 aut
700	1	a Hveem, Kristianu Norwegian Univ Sci & Technol, Dept Publ Hlth & Gen Practice, HUNT Res Ctr, Levanger, Norway.;Nord Trondelag Hlth Trust, Levanger Hosp, Dept Med, Levanger, Norway.4 aut
700	1	a Willer, Cristen J.u University of Michigan,Univ Michigan, Dept Internal Med, Div Cardiovasc Med, Ann Arbor, MI 48109 USA.;Univ Michigan, Dept Computat Med & Bioinformat, Ann Arbor, MI 48109 USA.;Univ Michigan, Dept Human Genet, Ann Arbor, MI 48109 USA.4 aut
700	1	a Tuomi, Tiinamaijau Helsinki University Central Hospital,University of Helsinki,Folkhälsan Research Center4 aut0 (Swepub:lu)ti8736tu
700	1	a Groop, Leifu Lund University,Lunds universitet,Translationell muskelforskning,Forskargrupper vid Lunds universitet,Translational Muscle Research,Lund University Research Groups,University of Helsinki,Univ Helsinki, Inst Mol Med Finland, Helsinki, Finland.;Lund Univ, Dept Clin Sci Diabet & Endocrinol, Ctr Diabet, Malmo, Sweden.4 aut0 (Swepub:lu)endo-lgr
700	1	a Käräjämäki, Annemariu Vaasa Central Hospital,Vaasa Cent Hosp, Dept Primary Hlth Care, Vaasa, Finland.;Vaasa Hlth Care Ctr, Ctr Diabet, Vaasa, Finland.4 aut
700	1	a Palotie, Aarnou Helsinki University Central Hospital,University of Helsinki,Broad Institute,Massachusetts General Hospital,Broad Inst, Program Med & Populat Genet, Cambridge, MA USA.;Massachusetts Gen Hosp, Dept Med, Analyt & Translat Genet Unit, Boston, MA 02114 USA.;Univ Helsinki, Inst Mol Med Finland, Helsinki, Finland.;Massachusetts Gen Hosp, Dept Psychiat, Psychiat & Neurodev Genet Unit, Boston, MA 02114 USA.4 aut0 (Swepub:lu)med-aop
700	1	a Ripatti, Samuliu University of Helsinki,Wellcome Trust Sanger Institute,Wellcome Trust Sanger Inst, Genome Campus, Hinxton, England.;Univ Helsinki, Inst Mol Med Finland, Helsinki, Finland.;Univ Helsinki, Dept Publ Hlth, Helsinki, Finland.4 aut0 (Swepub:lu)med-sur
700	1	a Salomaa, Veikkou Finnish National Institute for Health and Welfare,Natl Inst Hlth & Welf, Dept Hlth, Helsinki, Finland.4 aut
700	1	a Alam, Dewan S.u International Centre for Diarrhoeal Disease Research, Bangladesh,ICDDR, Dhaka, Bangladesh.4 aut
700	1	a Majumder, Abdulla Al Shafiu National Institute of Cardiovascular Diseases,Natl Inst Cardiovasc Dis, Dhaka, Bangladesh.4 aut
700	1	a Di Angelantonio, Emanueleu University of Cambridge,Univ Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge, England.;Univ Cambridge, NIHR Blbod & Transplant Res Unit Donor Hlth & Gen, Cambridge, England.4 aut
700	1	a Chowdhury, Rajivu University of Cambridge,Univ Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge, England.4 aut
700	1	a McCarthy, Mark I.u University of Oxford,Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, Oxford, England.;Univ Oxford, Radcliffe Dept Med, Ctr Diabet, Endocrinol & Metab, Oxford, England.;Oxford Univ Hosp Trusts, Natl Inst Hlth, Res Oxford Biomed Res Ctr, Oxford, England.4 aut
700	1	a Poulter, Neilu Imperial College London,Imperial Coll London, Sch Publ Hlth, London, England.4 aut
700	1	a Stanton, Alice V.u Royal College of Surgeons in Ireland,Royal Coll Surgeons Ireland, Mol & Cellular Therapeut, Dublin, Ireland.4 aut
700	1	a Sever, Peteru Imperial College London4 aut
700	1	a Amouyel, Philippeu Pasteur Institute of Lille,Univ Lille, UMR 1167, Risk Factors & Mol Determinants Aging Related Dis, Lille, France.;INSERM, Lille, France.;CHU Lille, Publ Hlth, Lille, France.;Inst Pasteur, Lille, France.4 aut
700	1	a Arveiler, Dominiqueu University of Strasbourg,Univ Strasbourg, Dept Epidemiol & Publ Hlth, EA 3430, Strasbourg, France.4 aut
700	1	a Blankenberg, Stefanu University Medical Center Hamburg-Eppendorf,Univ Heart Ctr Hamburg, Dept Gen & Intervent Cardiol, Hamburg, Germany.;Univ Med Ctr Hamburg Eppendorf, Hamburg, Germany.4 aut
700	1	a Ferrières, Jeanu University of Toulouse,Toulouse Univ, Dept Epidemiol, UMR 1027, INSERM,CHU Toulouse, Toulouse, France.4 aut
700	1	a Kee, Franku Queen's University Belfast,Queens Univ, UKCRC Ctr Excellence Publ Hlth, Belfast, Antrim, North Ireland.4 aut
700	1	a Kuulasmaa, Kariu Finnish National Institute for Health and Welfare4 aut
700	1	a Müller-Nurasyid, Martinau German Centre for Cardiovascular Research,Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Inst Genet Epidemiol, Neuherberg, Germany.;Univ Munich, Dept Med 1, Univ Hosp Grosshadern, Munich, Germany.;DZHK German Ctr Cardiovasc Res, Partner Site Munich Heart Alliance, Munich, Germany.4 aut
700	1	a Veronesi, Giovanniu University of Insubria,Univ Insubria, Dept Clin & Expt Med, Res Ctr Epidemiol & Prevent Med, Varese, Italy.4 aut
700	1	a Virtamo, Jarmou Finnish National Institute for Health and Welfare,Natl Inst Hlth & Welf, Dept Hlth, Helsinki, Finland.4 aut
700	1	a Deloukas, Panosu King Abdulaziz University,Queen Mary Univ London, William Harvey Res Inst, Bads & London Sch Med & Dent, Ctr Heart, London, England.;King Abdulaziz Univ, Princess Al Jawhara Al Brahim Ctr Excellence Res, Jeddah, Saudi Arabia.4 aut
700	1	a Elliott, Paulu Imperial College London,Imperial Coll London, Dept Epidemiol & Biostat, Med Res Council Publ Hlth England Ctr Environm &, Sch Publ Hlth,Fac Med, St Marys Campus, London, England.4 aut
700	1	a Zeggini, Eleftheriau Wellcome Trust Sanger Institute,Wellcome Trust Sanger Inst, Genome Campus, Hinxton, England.4 aut
700	1	a Kathiresan, Sekaru Boston University,Broad Inst, Program Med & Populat Genet, Cambridge, MA USA.;Massachusetts Gen Hosp, Ctr Human Genet Res, Boston, MA 02114 USA.;Massachusetts Gen Hosp, Boston, MA 02114 USA.;Harvard Med Sch, Dept Med, Boston, MA USA.4 aut
700	1	a Melander, Olleu Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups,Lund Univ, Dept Clin Sci, Malmo, Sweden.4 aut0 (Swepub:lu)endo-ome
700	1	a Kuusisto, Johannau University of Eastern Finland,Univ Eastern Finland, Dept Med, Kuopio, Finland.;Kuopio Univ Hosp, Kuopio, Finland.4 aut
700	1	a Laakso, Markkuu University of Eastern Finland,Univ Eastern Finland, Dept Med, Kuopio, Finland.;Kuopio Univ Hosp, Kuopio, Finland.4 aut
700	1	a Padmanabhan, Sandoshu University of Glasgow,Univ Glasgow, Coll Med Vet & Life Sci, Inst Cardiovasc & Med Sci, Glasgow, Lanark, Scotland.4 aut
700	1	a Porteous, David J.u University of Edinburgh,Univ Edinburgh, Med Res Council Inst Genet & Mol Med, Ctr Genom & Expt Med, Edinburgh, Midlothian, Scotland.4 aut
700	1	a Hayward, Carolineu University of Edinburgh,Univ Edinburgh, Med Res Council Human Genet Unit, Med Res Council Inst Genet & Mol Med, Edinburgh, Midlothian, Scotland.4 aut
700	1	a Scotland, Generationu National Health Service Trust, NHS England,Collaborat Univ Med Sch & NHS, Aberdeen, Scotland.;Collaborat Univ Med Sch & NHS, Dundee, Scotland.;Collaborat Univ Med Sch & NHS, Edinburgh, Midlothian, Scotland.;Collaborat Univ Med Sch & NHS, Glasgow, Lanark, Scotland.4 aut
700	1	a Collins, Francis S.u National Human Genome Research Institute4 aut
700	1	a Mohlke, Karen L.u University of North Carolina4 aut
700	1	a Hansen, Torbenu University of Copenhagen,Univ Copenhagen, Fac Hlth & Med Sci, Novo Nordisk Fdn Ctr Basic Metab Res, Copenhagen, Denmark.4 aut
700	1	a Pedersen, Olufu University of Copenhagen,Univ Copenhagen, Fac Hlth & Med Sci, Novo Nordisk Fdn Ctr Basic Metab Res, Copenhagen, Denmark.4 aut
700	1	a Boehnke, Michaelu University of Michigan,Univ Michigan, Ctr Stat Genet, Ann Arbor, MI 48109 USA.;Univ Michigan, Dept Biostat, Ann Arbor, MI USA.4 aut
700	1	a Stringham, Heather M.u University of Michigan,Univ Michigan, Ctr Stat Genet, Ann Arbor, MI 48109 USA.;Univ Michigan, Dept Biostat, Ann Arbor, MI USA.4 aut
700	1	a Frossard, Philippeu Centre for Non-Communicable Diseases,Ctr Noncommunicable Dis, Karachi, Pakistan.4 aut
700	1	a Newton-Cheh, Christopheru Massachusetts General Hospital,Broad Inst, Program Med & Populat Genet, Cambridge, MA USA.;Massachusetts Gen Hosp, Ctr Human Genet Res, Boston, MA 02114 USA.;Massachusetts Gen Hosp, Boston, MA 02114 USA.4 aut
700	1	a Tobin, Martin D.u University of Leicester,Univ Leicester, Dept Hlth Sci, Leicester, Leics, England.4 aut
700	1	a Nordestgaard, Børge Grønneu Copenhagen University Hospital,Copenhagen Univ Hosp, Dept Clin Biochem, Herlev Hosp, Herlev, Denmark.4 aut
700	1	a Caulfield, Mark J.u Queen Mary University,Queen Mary Univ London, William Harvey Res Inst, Clin Pharmacol, London, England.;Queen Mary Univ London, Natl Inst Hlth Res, Barts Cardiovasc Biomed Res Unit, London, England.4 aut
700	1	a Mahajan, Anubhau University of Oxford,Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, Oxford, England.4 aut
700	1	a Morris, Andrew P.u University of Oxford,Univ Liverpool, Dept Biostat, Liverpool, Merseyside, England.;Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, Oxford, England.4 aut
700	1	a Tomaszewski, Macieju University of Manchester,Univ Leicester, Dept Cardiovasc Sci, Leicester, Leics, England.;Natl Inst Hlth, Res Leicester Biomed Res Unit Cardiovasc Dis, Leicester, Leics, England.;Univ Manchester, Div Cardiovasc Sci, Manchester, Lancs, England.4 aut
700	1	a Samani, Nilesh J.u National Institute for Health Research, United Kingdom,Univ Leicester, Dept Cardiovasc Sci, Leicester, Leics, England.;Natl Inst Hlth, Res Leicester Biomed Res Unit Cardiovasc Dis, Leicester, Leics, England.4 aut
700	1	a Saleheen, Danishu University of Pennsylvania,Univ Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge, England.;Ctr Noncommunicable Dis, Karachi, Pakistan.;Univ Penn, Dept Biostat & Epidemiol, Perelman Sch Med, Philadelphia, PA 19104 USA.4 aut
700	1	a Asselbergs, Folkert W.u University College London,Univ Med Ctr Utrecht, Dept Cardiol, Utrecht, Netherlands.;ICIN Netherlands Heart Inst, Durrer Ctr Cardiogenet Res, Utrecht, Netherlands.;UCL, Inst Cardiovasc Sci, Fac Populat Hlth Sci, London, England.4 aut
700	1	a Lindgren, Cecilia M.u University of Oxford,Broad Institute,Broad Inst, Program Med & Populat Genet, Cambridge, MA USA.;Univ Oxford, Nuffield Dept Med, Wellcome Trust Ctr Human Genet, Oxford, England.;Univ Oxford, Big Data Inst, Li Ka Shing Ctr Hlth Informat & Discovery, Oxford, England.4 aut0 (Swepub:lu)endo-cli
700	1	a Danesh, Johnu Wellcome Trust Sanger Institute,Univ Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge, England.;Univ Cambridge, NIHR Blbod & Transplant Res Unit Donor Hlth & Gen, Cambridge, England.;Wellcome Trust Sanger Inst, Hinxton, England.4 aut
700	1	a Wain, Louise V.u University of Leicester,Univ Leicester, Dept Hlth Sci, Leicester, Leics, England.4 aut
700	1	a Butterworth, Adam S.u University of Cambridge,Univ Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge, England.;Univ Cambridge, NIHR Blbod & Transplant Res Unit Donor Hlth & Gen, Cambridge, England.4 aut
700	1	a Howson, Joanna M Mu University of Cambridge,Univ Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge, England.4 aut
700	1	a Munroe, Patricia B.u Queen Mary University,Queen Mary Univ London, William Harvey Res Inst, Clin Pharmacol, London, England.;Queen Mary Univ London, Natl Inst Hlth Res, Barts Cardiovasc Biomed Res Unit, London, England.;Wellcome Trust Sanger Inst, Hinxton, England.4 aut
710	2	a University of Cambridgeb Univ Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge, England.4 org
773	0	t Nature Geneticsd : Springer Science and Business Media LLCg 48:10, s. 1151-1161q 48:10<1151-1161x 1061-4036x 1546-1718
856	4	u http://dx.doi.org/10.1038/ng.3654y FULLTEXT
856	4	u https://europepmc.org/articles/pmc5056636?pdf=render
856	4 8	u https://lup.lub.lu.se/record/916bdc2c-1aae-4d2e-ae43-b0b6f891545c
856	4 8	u https://doi.org/10.1038/ng.3654
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-127953
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-306251

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