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Changes in inflamma...
Changes in inflammatory bowel disease subtype during follow-up and over time in 44,302 patients
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- Everhov, Åsa H. (författare)
- Karolinska Institutet,Karolinska Inst, Sweden; Karolinska Inst, Sweden
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- Sachs, Michael C (författare)
- Karolinska Institutet,Karolinska Inst, Sweden
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- Malmborg, Petter (författare)
- Karolinska Institutet,Karolinska Inst, Sweden; Karolinska Inst, Sweden
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- Nordenvall, Caroline (författare)
- Karolinska Institutet,Karolinska Inst, Sweden; Karolinska Univ Hosp, Sweden
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- Myrelid, Pär (författare)
- Linköpings universitet,Avdelningen för Kirurgi, Ortopedi och Onkologi,Medicinska fakulteten,Region Östergötland, Kirurgiska kliniken US
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- Khalili, Hamed (författare)
- Clinical Epidemiology Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Gastroenterology Unit, Crohn's and Colitis Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA,Karolinska Inst, Sweden; Harvard Med Sch, MA 02115 USA
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- Elmberg, Maria (författare)
- Clinical Epidemiology Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden
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- Ekbom, Anders (författare)
- Karolinska Institutet,Karolinska Inst, Sweden
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- Askling, Johan (författare)
- Karolinska Institutet,Karolinska Inst, Sweden
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- Jakobsson, Gustav (författare)
- Department Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden,Karolinska Inst, Sweden
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- Halfvarson, Jonas, 1970- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Department of Gastroenterology,Orebro Univ, Sweden
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- Ludvigsson, Jonas F., 1969- (författare)
- Karolinska Institutet,Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Department of Gastroenterology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden; Department of Pediatrics, Örebro University Hospital, Örebro University, Örebro, Sweden; Division of Epidemiology and Public Health, School of Medicine, University of Nottingham, Nottingham, UK; Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA,Karolinska Inst, Sweden; Orebro Univ, Sweden; Orebro Univ, Sweden; Univ Nottingham, England; Columbia Univ Coll Phys and Surg, NY USA
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- Olén, Ola (författare)
- Karolinska Institutet,Karolinska Inst, Sweden; Sachs Children and Youth Hosp, Sweden
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(creator_code:org_t)
- 2019-01-31
- 2019
- Engelska.
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Ingår i: Scandinavian Journal of Gastroenterology. - : Taylor & Francis. - 0036-5521 .- 1502-7708. ; 54:1, s. 55-63
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https://doi.org/10.1...
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https://liu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- AIM: To investigate inflammatory bowel disease (IBD) register-based subtype classifications over a patient's disease course and over time.METHODS: We examined International Classification of Diseases coding in patients with ≥2 IBD diagnostic listings in the National Patient Register 2002-2014 (n = 44,302).RESULTS: 18% of the patients changed diagnosis (17% of adults, 29% of children) during a median follow-up of 3.8 years. Of visits with diagnoses of Crohn's disease (CD) or ulcerative colitis (UC), 97% were followed by the same diagnosis, whereas 67% of visits with diagnosis IBD-unclassified (IBD-U) were followed by another IBD-U diagnosis. Patients with any diagnostic change changed mostly once (47%) or twice (31%), 39% from UC to CD, 33% from CD to UC and 30% to or from IBD-U. Using a classification algorithm based on the first two diagnoses ('incident classification'), suited for prospective cohort studies, the proportion adult patients with CD, UC, and IBD-U 2002-2014 were 29%, 62%, and 10% (43%, 45%, and 12% in children). A classification model incorporating additional information from surgeries and giving weight to the last 5 years of visits ('prevalent classification'), suited for description of a study population at end of follow-up, classified 31% of adult cases as CD, 58% as UC and 11% as IBD-U (44%, 38%, and 18% in children).CONCLUSIONS: IBD subtype changed in 18% during follow-up. The proportion with CD increased and UC decreased from definition at start to end of follow-up. IBD-U was more common in children.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Gastroenterologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)
Nyckelord
- Crohn’s disease
- IBD-U
- Inflammatory bowel disease
- indeterminate colitis
- inflammatory bowel disease unclassified
- register-based definition
- ulcerative colitis
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Till lärosätets databas
- Av författaren/redakt...
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Everhov, Åsa H.
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Sachs, Michael C
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Malmborg, Petter
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Nordenvall, Caro ...
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Myrelid, Pär
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Khalili, Hamed
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Elmberg, Maria
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Ekbom, Anders
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Askling, Johan
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Jakobsson, Gusta ...
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Halfvarson, Jona ...
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Ludvigsson, Jona ...
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Olén, Ola
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Gastroenterologi
- Artiklar i publikationen
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Scandinavian Jou ...
- Av lärosätet
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Örebro universitet
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Karolinska Institutet
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Linköpings universitet