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SARS-CoV-2 emerging...
SARS-CoV-2 emerging Omicron subvariants with a special focus on BF.7 and XBB.1.5 recently posing fears of rising cases amid ongoing COVID-19 pandemic
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- Dhama, Kuldeep (författare)
- Division of Pathology, ICAR-Indian Veterinary Research Institute, Bareilly, Uttar Pradesh-, 243122, India, Uttar Pradesh
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- Chandran, Deepak (författare)
- Department of Veterinary Sciences and Animal Husbandry, Amrita School of Agricultural Sciences, Amrita Vishwa Vidyapeetham University, Coimbatore, Tamil Nadu, India, 642109, Tamil Nadu
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- Chopra, Hitesh (författare)
- Chitkara College of Pharmacy, Chitkara University, Punjab, India-, 140401, Punjab
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- Aminul Islam, Md (författare)
- COVID-19 Diagnostic Lab, Department of Microbiology, Noakhali Science and Technology University, Noakhali-, 3814, Bangladesh, Noakhali; Advanced Molecular Lab, Department of Microbiology, President Abdul Hamid Medical College, Karimganj, Kishoreganj-, 834001, Bangladesh, Karimganj
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- Emran, Talha Bin (författare)
- Department of Pharmacy, BGC Trust University Bangladesh, Chittagong, 4381, Bangladesh; Department of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, Dhaka, 1207, Bangladesh
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- Rehman, Mohammad Ebad Ur (författare)
- Department of Medicine, Rawalpindi Medical University, Rawalpindi-, 46000, Pakistan
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- Dey, Abhijit (författare)
- Department of Life Sciences, Presidency University, 86/1 College Street, Kolkata-, 700073, West Bengal, India, 86/1 College Street, West Bengal
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- Mohapatra, Ranjan K. (författare)
- Department of Chemistry, Government College of Engineering, Keonjhar, 758 002, Odisha, India, Odisha
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- Praveen, S. V. (författare)
- National Institute of Technology, Tiruchirappalli, 620015, Tamil Nadu, India, Tamil Nadu
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- Mohankumar, Pran (författare)
- School of Agricultural Sciences, Karunya Institute of Technology and Sciences, Coimbatore, Tamil Nadu, India-, 641114, Tamil Nadu
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- Sharma, Anil Kumar (författare)
- Department of Biotechnology, Maharishi Markandeshwar University (Deemed to be University) Mullana-Ambala-, 133207, Haryana, India, Haryana
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- Bhattacharya, Prosun, 1962- (författare)
- KTH,Hållbar utveckling, miljövetenskap och teknik
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(creator_code:org_t)
- 2022-12-31
- 2022
- Engelska.
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Ingår i: Journal of Experimental Biology and Agricultural Sciences. - : JEBAS. - 2320-8694. ; 10:6, s. 1215-1221
- Relaterad länk:
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron versions have been the sole one circulating for quite some time. Subvariants BA.1, BA.2, BA.3, BA.4, and BA.5 of the Omicron emerged over time and through mutation, with BA.1 responsible for the most severe global pandemic between December 2021 and January 2022. Other Omicron subvariants such as BQ.1, BQ.1.1, BA.4.6, BF.7, BA.2.75.2, XBB.1 appeared recently and could cause a new wave of increased cases amid the ongoing COVID-19 pandemic. There is evidence that certain Omicron subvariants have increased transmissibility, extra spike mutations, and ability to overcome protective effects of COVID-19 neutralizing antibodies through immunological evasion. In recent months, the Omicron BF.7 subvariant has been in the news due to its spread in China and a small number of other countries, raising concerns about a possible rebound in COVID-19 cases. More recently, the Omicron XBB.1.5 subvariant has captured international attention due to an increase in cases in the United States. As a highly transmissible sublineage of Omicron BA.5, as well as having a shorter incubation time and the potential to reinfect or infect immune population, BF.7 has stronger infection ability. It appears that the regional immunological landscape is affected by the amount and timing of previous Omicron waves, as well as the COVID-19 vaccination coverage, which in turn determines whether the increased immune escape of BF.7 and XBB.1.5 subvariants is sufficient to drive new infection waves. Expanding our understanding of the transmission and efficacy of vaccines, immunotherapeutics, and antiviral drugs against newly emerging Omicron subvariants and lineages, as well as bolstering genomic facilities for tracking their spread and maintaining a constant vigilance, and shedding more light on their evolution and mutational events, would help in the development of effective mitigation strategies. Importantly, reducing the occurrence of mutations and recombination in the virus can be aided by bolstering One health approach and emphasizing its significance in combating zoonosis and reversal zoonosis linked with COVID-19. This article provides a brief overview on Omicron variant, its recently emerging lineages and subvairants with a special focus on BF.7 and XBB.1.5 as much more infectious and highly transmissible variations that may once again threaten a sharp increase in COVID-19 cases globally amid the currently ongoing pandemic, along with presenting salient mitigation measures.
Ämnesord
- NATURVETENSKAP -- Biologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Andra medicinska och farmaceutiska grundvetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Other Basic Medicine (hsv//eng)
Nyckelord
- COVID-19
- Mitigation strategies
- Omicron subvariants
- Pandemic
- Rising cases
- SARS-CoV-2
- Variants
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- ref (ämneskategori)
- art (ämneskategori)
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Dhama, Kuldeep
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Chandran, Deepak
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Chopra, Hitesh
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Aminul Islam, Md
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Emran, Talha Bin
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Rehman, Mohammad ...
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Dey, Abhijit
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Mohapatra, Ranja ...
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Praveen, S. V.
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Mohankumar, Pran
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Sharma, Anil Kum ...
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Bhattacharya, Pr ...
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