Sökning: (WFRF:(Raposo G)) > A brief history of ...
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 03199naa a2200625 4500 | |
001 | oai:gup.ub.gu.se/312742 | |
003 | SwePub | |
008 | 240528s2021 | |||||||||||000 ||eng| | |
024 | 7 | a https://gup.ub.gu.se/publication/3127422 URI |
024 | 7 | a https://doi.org/10.1002/jev2.121442 DOI |
040 | a (SwePub)gu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Couch, Y.4 aut |
245 | 1 0 | a A brief history of nearly EV-erything - The rise and rise of extracellular vesicles |
264 | c 2021-12-17 | |
264 | 1 | b Wiley,c 2021 |
520 | a Extracellular vesicles (EVs) are small cargo-bearing vesicles released by cells into the extracellular space. The field of EVs has grown exponentially over the past two decades; this growth follows the realisation that EVs are not simply a waste disposal system as had originally been suggested by some, but also a complex cell-to-cell communication mechanism. Indeed, EVs have been shown to transfer functional cargo between cells and can influence several biological processes. These small biological particles are also deregulated in disease. As we approach the 75th anniversary of the first experiments in which EVs were unknowingly isolated, it seems right to take stock and look back on how the field started, and has since exploded into its current state. Here we review the early experiments, summarise key findings that have propelled the field, describe the growth of an organised EV community, discuss the current state of the field, and identify key challenges that need to be addressed. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicin0 (SwePub)3022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicine0 (SwePub)3022 hsv//eng |
653 | a ectosome | |
653 | a exosome | |
653 | a extracellular vesicle | |
653 | a microparticle | |
653 | a microvesicle | |
653 | a cell-derived exosomes | |
653 | a virus-like particles | |
653 | a trypsin-like-enzyme | |
653 | a transferrin receptor | |
653 | a membrane-vesicles | |
653 | a platelet microparticles | |
653 | a reticulocyte maturation | |
653 | a multivesicular body | |
653 | a proteomic analysis | |
653 | a human | |
653 | a neutrophils | |
653 | a Cell Biology | |
700 | 1 | a Buzas, E. I.4 aut |
700 | 1 | a Vizio, D. D.4 aut |
700 | 1 | a Gho, Y. S.4 aut |
700 | 1 | a Harrison, P.4 aut |
700 | 1 | a Hill, A. F.4 aut |
700 | 1 | a Lötvall, Jan,d 1956u Gothenburg University,Göteborgs universitet,Institutionen för medicin,Krefting Research Centre,Institute of Medicine4 aut0 (Swepub:gu)xlotja |
700 | 1 | a Raposo, G.4 aut |
700 | 1 | a Stahl, P. D.4 aut |
700 | 1 | a Thery, C.4 aut |
700 | 1 | a Witwer, K. W.4 aut |
700 | 1 | a Carter, D. R. F.4 aut |
710 | 2 | a Göteborgs universitetb Institutionen för medicin4 org |
773 | 0 | t Journal of Extracellular Vesiclesd : Wileyg 10:14q 10:14x 2001-3078 |
856 | 4 | u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jev2.12144 |
856 | 4 8 | u https://gup.ub.gu.se/publication/312742 |
856 | 4 8 | u https://doi.org/10.1002/jev2.12144 |
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