Sökning: WFRF:(Östman S.) > Beta-blockers and t...
Fältnamn | Indikatorer | Metadata |
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000 | 03880naa a2200397 4500 | |
001 | oai:DiVA.org:umu-100619 | |
003 | SwePub | |
008 | 150305s1982 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1006192 URI |
040 | a (SwePub)umu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Reiz, S.u Umeå universitet,Anestesiologi och intensivvård4 aut |
245 | 1 0 | a Beta-blockers and thoracic epidural analgesia. Cardioprotective and synergistic effects |
264 | 1 | c 1982 |
338 | a print2 rdacarrier | |
500 | a Reiz, S Haggmark, S Rydvall, A Ostman, M Denmark Acta anaesthesiologica Scandinavica. Supplementum Acta Anaesthesiol Scand Suppl. 1982;76:54-61. | |
520 | a Seven groups of patients with and without hypertension or with ischaemic heart disease, treated with different beta blockers were investigated to study the circulatory effects of neurolept anaesthesia alone or combined with thoracic epidural analgesia from T4 to T12/L2 during abdominal surgery. The combination of thoracic epidural analgesia and neurolept anaesthesia in hypertensive subjects treated with non-cardioselective beta blockers induced slightly lower blood pressure than measured in similar patients on cardioselective beta blockers with neurolept anaesthesia only. Patients on non-selective beta blockers with intrinsic stimulatory activity (ISA) had higher blood pressure and heart rate after neurolept anaesthesia induction than patients on cardioselective blockers. During surgery, heart rate remained at a higher level in the patients treated with ISA blockers, whereas blood pressure increased to the same level as in patients with cardioselective blockers. Cardiovascular stability was, however, best maintained in the epidural group, where myocardial energy expenditure during maximal surgical stress was comparable to that in a group of healthy subjects with the same format of anaesthesia and significantly lower than in healthy subjects with neurolept anaesthesia alone. No circulatory side effects of the combination of thoracic epidural analgesia and beta blockade were seen. In patients with ischaemic heart disease, with or without non-selective beta blockade, similar haemodynamic changes were recorded following neurolept anaesthesia. During maximal surgical stress, unmasking of alpha adrenergic activity with marked rise in blood pressure was seen in the beta-blocked patients. Despite the more accelerated haemodynamic changes in the blocked patients, a lower increase in myocardial oxygen consumption was recorded compared with the non-blocked patients.(ABSTRACT TRUNCATED AT 250 WORDS) | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Anestesi och intensivvård0 (SwePub)302012 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Anesthesiology and Intensive Care0 (SwePub)302012 hsv//eng |
653 | a Adrenergic beta-Antagonists/*therapeutic use | |
653 | a *Analgesia | |
653 | a Epidural | |
653 | a Coronary Disease/drug therapy/physiopathology/*surgery | |
653 | a Hemodynamics | |
653 | a Humans | |
653 | a Hypertension/drug therapy/physiopathology/*surgery | |
700 | 1 | a Häggmark, S.u Umeå universitet,Anestesiologi och intensivvård4 aut0 (Swepub:umu)kaso0008 |
700 | 1 | a Rydvall, A.u Umeå universitet,Anestesiologi och intensivvård4 aut0 (Swepub:umu)anry0024 |
700 | 1 | a Östman, M.u Umeå universitet,Anestesiologi och intensivvård4 aut |
710 | 2 | a Umeå universitetb Anestesiologi och intensivvård4 org |
773 | 0 | t Acta Anaesthesiol Scand Supplg 76, s. 54-61q 76<54-61 |
856 | 4 | u http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6152883 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-100619 |
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