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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003452naa a2200397 4500
001oai:gup.ub.gu.se/330380
003SwePub
008240626s2024 | |||||||||||000 ||eng|
0247 a https://gup.ub.gu.se/publication/3303802 URI
0247 a https://doi.org/10.1016/j.jacc.2023.11.0022 DOI
040 a (SwePub)gu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Redfors, Björnu Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine4 aut0 (Swepub:gu)xredbj
2451 0a Outcomes According to Coronary Revascularization Modality in the ISCHEMIA Trial.
264 1c 2024
520 a In the ISCHEMIA trial, the risk of ischemic events was similar in patients with stable coronary artery disease treated with an invasive (INV) strategy of angiography and percutaneous (PCI) or surgical (CABG) coronary revascularization and a conservative (CON) strategy of initial medical therapy.To analyze separately the outcomes of INV patients treated with PCI or CABG.Patients without preceding primary outcome events were categorized as INV-PCI or INV-CABG from the time of revascularization. The ISCHEMIA primary outcome (composite of cardiovascular death, protocol-defined myocardial infarction (MI) or hospitalization for unstable angina, heart failure or resuscitated cardiac arrest) was used.Among INV-CABG patients, primary outcome events occurred in 84/512 (16.4%) at median follow-up of 2.85 years; 48 events (57.1%) occurred within 30 days after CABG, including 40 procedural MIs; among INV-PCI patients, primary outcome events occurred in 147/1500 (9.8%) at median follow-up of 2.94 years; 31 of which (21.1%) within 30 days after PCI, including 23 procedural MIs. In comparison, 352/2591 (13.6%) CON patients had primary outcome events at median follow-up 3.2 years, 22 of which (6.3%) within 30 days of randomization. The adjusted primary outcome risks (HR [95%CI]) were higher after both CABG and PCI within 30 days (16.25 (11.44-23.07) and 2.99 (1.97-4.53)) and lower thereafter (0.63 (0.44-0.89) and 0.66(0.53-0.82)).In ISCHEMIA, early revascularization by PCI and CABG was associated with higher early risks and lower long-term risks of cardiovascular events compared with CON. The early risk was greatest after CABG, due to protocol-defined procedural MIs.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
7001 a Stone, Gregg W4 aut
7001 a Alexander, John H4 aut
7001 a Bates, Eric R4 aut
7001 a Bhatt, Deepak L4 aut
7001 a Biondi-Zoccai, Giuseppe4 aut
7001 a Caldonazo, Tulio4 aut
7001 a Farkouh, Michael4 aut
7001 a Rahouma, Mohamed4 aut
7001 a Puskas, John4 aut
7001 a Sandner, Sigrid4 aut
7001 a Gaudino, Mario Fl4 aut
7102 a Göteborgs universitetb Institutionen för medicin, avdelningen för molekylär och klinisk medicin4 org
7730 t Journal of the American College of Cardiologyg 83:5, s. 549-558q 83:5<549-558x 1558-3597
8564 8u https://gup.ub.gu.se/publication/330380
8564 8u https://doi.org/10.1016/j.jacc.2023.11.002

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