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FältnamnIndikatorerMetadata
00005669naa a2200469 4500
001oai:lup.lub.lu.se:df14757e-60f6-483a-92db-1f5805aaefab
003SwePub
008171021s2018 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:137789008
0247 a https://lup.lub.lu.se/record/df14757e-60f6-483a-92db-1f5805aaefab2 URI
0247 a https://doi.org/10.1093/europace/eux0322 DOI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1377890082 URI
040 a (SwePub)lud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a Johnson, Linda S Bu Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)med-laj
2451 0a ST segment depression on 24-hour electrocardiography predicts incident atrial fibrillation in two population-based cohorts
264 c 2017-04-10
264 1b Oxford University Press (OUP),c 2018
520 a Aims: ST-depression at 24hECG has not been studied in relation to atrial fibrillation (AF) risk. We aimed to determine whether ST-depression at 24hECG was associated with incident AF in two Swedish population-based cohorts - a sub-cohort of the Malmö Diet and Cancer study (MDCS), and the cohort 'Men born in 1914', and to determine whether 24hECG could be used to predict AF development.Methods and results: There were 378 acceptable 24hECG recordings in the MDCS (mean age 64.5 years, 43% men) and 394 acceptable recordings in 'Men born in 1914' (mean age 68.8 years). Incidence of AF was monitored using national registers of hospitalizations and outpatient visits in Sweden. Mean follow-up ± SD (cumulative incidence) was 10.4 ± 2 years (11.3%) in MDCS, and 10.9 ± 4 years (7.3%) in 'Men born in 1914'. ST-depressions were independently associated with incident AF; hazard ratio (HR) (95% CI) 2.41 (1.29-4.50, P = 0.006) and 2.28 (1.05-4.95, P = 0.038) after adjustment [age, sex, height, weight, systolic blood pressure, smoking, anti-hypertensive drugs, LDL/total cholesterol, and HOMA-IR (in MDCS)]. AF incidence was substantially lower in individuals who had neither ST-depressions or high supraventricular activity (SVA, negative predictive value 0.97 and 0.94, in MDCS and 'Men born in 1914', respectively), and similar in men and women.Conclusion: ST-depression at 24h-ECG is independently associated with incident AF, and incidence is substantially lower in individuals with neither ST-depression or high SVA. 24hECG can be used not only to diagnose AF but also to identify individuals at high and low AF risk.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
653 a Journal Article
7001 a Berntsson, Johnu Lund University,Lunds universitet,Kardiovaskulär forskning - epidemiologi,Forskargrupper vid Lunds universitet,Molecular Epidemiology and Cardiology,Cardiovascular Research - Epidemiology,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)med-jhb
7001 a Juhlin, Tordu Lund University,Lunds universitet,Kardiologiska klinikens forskargrupp,Forskargrupper vid Lunds universitet,Cardiology Research Group,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)medf-tju
7001 a Healey, Jeff Su McMaster University4 aut
7001 a Juul-Möller, Steenu Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)medf-sju
7001 a Wollmer, Peru Lund University,Lunds universitet,Klinisk fysiologi och nuklearmedicin, Malmö,Forskargrupper vid Lunds universitet,Clinical Physiology and Nuclear Medicine, Malmö,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)klin-pwo
7001 a Nilsson, Peter Mu Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)medf-pni
7001 a Hedblad, Bou Lund University,Lunds universitet,Kardiovaskulär forskning - epidemiologi,Forskargrupper vid Lunds universitet,Cardiovascular Research - Epidemiology,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)medf-bhe
7001 a Rosenqvist, Mårtenu Karolinska Institutet,Karolinska Institute4 aut
7001 a Engström, Gunnaru Lund University,Lunds universitet,Kardiovaskulär forskning - epidemiologi,Forskargrupper vid Lunds universitet,Cardiovascular Research - Epidemiology,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)smi-gen
7102 a Internmedicin - epidemiologib Forskargrupper vid Lunds universitet4 org
7730 t Europaced : Oxford University Press (OUP)g 20:3, s. 429-434q 20:3<429-434x 1532-2092
7730 t EP Europaced : Oxford University Press (OUP)g 20:3, s. 429-434q 20:3<429-434x 1099-5129
8564 u http://dx.doi.org/10.1093/europace/eux032y FULLTEXT
8564 u https://academic.oup.com/europace/article-pdf/20/3/429/24186265/eux032.pdf
8564 8u https://lup.lub.lu.se/record/df14757e-60f6-483a-92db-1f5805aaefab
8564 8u https://doi.org/10.1093/europace/eux032
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:137789008

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