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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004896naa a2200517 4500
001oai:DiVA.org:uu-491759
003SwePub
008221222s2023 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4917592 URI
0247 a https://doi.org/10.1021/acs.jproteome.2c004982 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Omenn, Gilbert S.u University of Michigan, Ann Arbor, Michigan 48109, United States;Institute for Systems Biology, Seattle, Washington 98109, United States4 aut
2451 0a The 2022 Report on the Human Proteome from the HUPO Human Proteome Project
264 c 2022-11-01
264 1b American Chemical Society (ACS),c 2023
338 a print2 rdacarrier
520 a The 2022 Metrics of the Human Proteome from the HUPO Human Proteome Project (HPP) show that protein expression has now been credibly detected (neXtProt PE1 level) for 18 407 (93.2%) of the 19 750 predicted proteins coded in the human genome, a net gain of 50 since 2021 from data sets generated around the world and reanalyzed by the HPP. Conversely, the number of neXtProt PE2, PE3, and PE4 missing proteins has been reduced by 78 from 1421 to 1343. This represents continuing experimental progress on the human proteome parts list across all the chromosomes, as well as significant reclassifications. Meanwhile, applying proteomics in a vast array of biological and clinical studies continues to yield significant findings and growing integration with other omics platforms. We present highlights from the Chromosome-Centric HPP, Biology and Disease-driven HPP, and HPP Resource Pillars, compare features of mass spectrometry and Olink and Somalogic platforms, note the emergence of translation products from ribosome profiling of small open reading frames, and discuss the launch of the initial HPP Grand Challenge Project, “A Function for Each Protein”.
650 7a NATURVETENSKAPx Biologix Bioinformatik och systembiologi0 (SwePub)106102 hsv//swe
650 7a NATURAL SCIENCESx Biological Sciencesx Bioinformatics and Systems Biology0 (SwePub)106102 hsv//eng
653 a Biologi
653 a Biology
7001 a Lane, Lydieu CALIPHO Group, SIB Swiss Institute of Bioinformatics and University of Geneva, 1015 Lausanne, Switzerland4 aut
7001 a Overall, Christopher M.u University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada4 aut
7001 a Pineau, Charlesu French Institute of Health and Medical Research, 35042 RENNES Cedex France4 aut
7001 a Packer, Nicolle H.u Macquarie University, Sydney, New South Wales 2109, Australia,;Griffith University’s Institute for Glycomics, Sydney, New South Wales 2109, Australia4 aut
7001 a Cristea, Ileana M.u Princeton University, Princeton, New Jersey 08544, United States4 aut
7001 a Lindskog, Ceciliau Uppsala universitet,Science for Life Laboratory, SciLifeLab,Cancerprecisionsmedicin,Uppsala University, 752 36 Uppsala, Sweden4 aut0 (Swepub:uu)cecli129
7001 a Weintraub, Susan T.u University of Texas Health Science Center-San Antonio, San Antonio, Texas 78229-3900, United States4 aut
7001 a Orchard, Sandrau EMBL-EBI, Hinxton, Cambridgeshire CB10 1SD, United Kingdom4 aut
7001 a Roehrl, Michael H. A.u Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States4 aut
7001 a Nice, Edouardu Monash University, Clayton Victoria 3800, Australia4 aut
7001 a Liu, Siqiu BGI Group, Shenzhen 518083, P. R. China4 aut
7001 a Bandeira, Nunou University of California, San Diego, La Jolla, California 92093, United States4 aut
7001 a Chen, Yu-Juu National Taiwan University, Academia Sinica, Nankang, Taipei 11529, Taiwan4 aut
7001 a Guo, Tiannanu Westlake University Guomics Laboratory of Big Proteomic Data, Hangzhou 310024, Zhejiang Province P. R. China4 aut
7001 a Aebersold, Ruediu Institute of Molecular Systems Biology in ETH Zurich, 8092 Zurich, Switzerland4 aut
7001 a Moritz, Robert L.u Institute for Systems Biology, Seattle, Washington 98109, United States4 aut
7001 a Deutsch, Eric W.u Institute for Systems Biology, Seattle, Washington 98109, United States4 aut
7102 a University of Michigan, Ann Arbor, Michigan 48109, United States;Institute for Systems Biology, Seattle, Washington 98109, United Statesb CALIPHO Group, SIB Swiss Institute of Bioinformatics and University of Geneva, 1015 Lausanne, Switzerland4 org
7730 t Journal of Proteome Researchd : American Chemical Society (ACS)g 22:4, s. 1024-1042q 22:4<1024-1042x 1535-3893x 1535-3907
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-491759
8564 8u https://doi.org/10.1021/acs.jproteome.2c00498

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