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FältnamnIndikatorerMetadata
00007991naa a2200673 4500
001oai:DiVA.org:uu-533106
003SwePub
008240625s2024 | |||||||||||000 ||eng|
009oai:DiVA.org:umu-223032
009oai:lup.lub.lu.se:ae76ad2e-73c8-401a-adae-ee145996bc66
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5331062 URI
0247 a https://doi.org/10.1016/j.euo.2023.12.0072 DOI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-2230322 URI
0247 a https://lup.lub.lu.se/record/ae76ad2e-73c8-401a-adae-ee145996bc662 URI
040 a (SwePub)uud (SwePub)umud (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Corsini, Christianu Uppsala University,Uppsala universitet,Institutionen för kirurgiska vetenskaper,IRCCS San Raffaele Hosp, Urol Res Inst, Div Expt Oncol, Unit Urol, Milan, Italy.,Department of Surgical Sciences, Uppsala University, Uppsala, Sweden; Division of Experimental Oncology/Unit of Urology, Urological Research Institute, IRCCS San Raffaele Hospital, Milan, Italy4 aut
2451 0a Patient-reported Side Effects 1 Year After Radical Prostatectomy or Radiotherapy for Prostate Cancer :b A Register-based Nationwide Study
264 1b Elsevier,c 2024
338 a print2 rdacarrier
520 a Background: Data on functional and psychological side effects following curative treatment for prostate cancer are lacking from large, contemporary, unselected, populationbased cohorts. Objective: To assess urinary symptoms, bowel disturbances, erectile dysfunction (ED), and quality of life (QoL) 12 mo after robot -assisted radical prostatectomy (RARP) and radiotherapy (RT) using patient -reported outcome measures in the Swedish prostate cancer database. Design, setting, and participants: This was a nationwide, population -based, cohort study in Sweden of men who underwent primary RARP or RT between January 1, 2018 and December 31, 2020. Outcome measurements and statistical analysis: Absolute proportions and odds ratios (ORs) were calculated using multivariable logistic regression, with adjustment for clinical characteristics. Results and limitations: A total of 2557 men underwent RARP and 1741 received RT. Men who underwent RT were older (69 vs 65 yr) and had more comorbidities at baseline. After RARP, 13% of men experienced incontinence, compared to 6% after RT. The frequency of urinary bother was similar, at 18% after RARP and 18% after RT. Urgency to defecate was reported by 14% of men after RARP and 34% after RT. At 1 yr, 73% of men had ED after RARP, and 77% after RT. High QoL was reported by 85% of men after RARP and 78% of men after RT. On multivariable regression analysis, RT was associated with lower risks of urinary incontinence (OR 0.25, 95% confidence interval [CI] 0.19- 0.33), urinary bother (OR 0.79, 95% CI 0.66-0.95), and ED (OR 0.54, 95% CI 0.46-0.65), but higher risk of bowel symptoms (OR 2.86, 95% CI 2.42-3.39). QoL was higher after RARP than after RT (OR 1.34, 95% CI 1.12-1.61). Conclusions: Short-term specific side effects after curative treatment for prostate cancer significantly differed between RARP and RT in this large and unselected cohort. Nevertheless, the risk of urinary bother was lower after RT, while higher QoL was common after RARP. Patient summary: In our study of patients treated for prostate cancer, urinary bother and overall quality of life are comparable at 1 year after surgical removal of the prostate in comparison to radiotherapy, despite substantial differences in other side effects. (c) 2024 The Authors. Published by Elsevier B.V. on behalf of European Association of Urology. This is an open access article under the CC BY -NC -ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Urologi och njurmedicin0 (SwePub)302142 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Urology and Nephrology0 (SwePub)302142 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Omvårdnad0 (SwePub)303052 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Nursing0 (SwePub)303052 hsv//eng
653 a Prostate cancer
653 a Radical prostatectomy
653 a Radiotherapy
653 a Patient-reported outcomes
653 a Population-based study
653 a Patient-reported outcomes
653 a Population-based study
653 a Prostate cancer
653 a Radical prostatectomy
653 a Radiotherapy
7001 a Bergengren, Oskaru Uppsala University,Uppsala universitet,Urologkirurgi,Department of Surgical Sciences, Uppsala University, Uppsala, Sweden4 aut0 (Swepub:uu)oskka588
7001 a Carlsson, Stefanu Karolinska Univ Hosp, Dept Urol, Solna, Sweden.,Department of Urology, Karolinska University Hospital, Solna, Sweden4 aut
7001 a Garmo, Hansu Uppsala University,Uppsala universitet,Urologkirurgi,Department of Surgical Sciences, Uppsala University, Uppsala, Sweden4 aut0 (Swepub:uu)hga27600
7001 a Hjelm-Eriksson, Marieu St Goran Hosp, Dept Oncol, Stockholm, Sweden.,Department of Oncology, St. Göran Hospital, Stockholm, Sweden,Capio St. Görans Sjukhus4 aut
7001 a Fransson, Peru Umeå University,Umeå universitet,Institutionen för omvårdnad,Cancercentrum, Norrlands University Hospital, Umeå, Sweden,Umeå Univ, Dept Nursing, Umeå, Sweden.;Norrlands Univ Hosp, Canc Ctr, Umeå, Sweden.4 aut0 (Swepub:umu)perfrn96
7001 a Kindblom, Jonu Univ Gothenburg, Sahlgrenska Acad, Dept Oncol, Gothenburg, Sweden.,Department of Oncology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden4 aut
7001 a Robinson, Davidu Ryhov Hosp, Dept Urol, Jönköping, Sweden.,Department of Urology, Ryhov Hospital, Jönköping, Sweden,Ryhov County Hospital, Jönköping4 aut
7001 a Westerberg, Marcus,d 1990-u Uppsala University,Uppsala universitet,Urologkirurgi,Department of Surgical Sciences, Uppsala University, Uppsala, Sweden4 aut0 (Swepub:uu)marwe776
7001 a Stattin, Päru Uppsala University,Uppsala universitet,Urologkirurgi,Department of Surgical Sciences, Uppsala University, Uppsala, Sweden4 aut0 (Swepub:uu)parst892
7001 a Carlsson, Sigrid V.u University of Gothenburg,Lund University,Lunds universitet,Urologisk cancerforskning, Malmö,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Urological cancer, Malmö,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Memorial Sloan-Kettering Cancer Center,Mem Sloan Kettering Canc Ctr, Dept Surg Urol Serv, 1133 York Ave, New York, NY 10065 USA.;Mem Sloan Kettering Canc Ctr, Dept Epidemiol & Biostat, New York, NY USA.;Gothenburg Univ, Sahlgrenska Acad, Dept Urol, Gothenburg, Sweden.;Lund Univ, Med Fac, Dept Translat Med, Div Urol Canc, Lund, Sweden.4 aut0 (Swepub:lu)si5270ca
7102 a Uppsala universitetb Institutionen för kirurgiska vetenskaper4 org
7730 t European Urology Oncologyd : Elsevierg 7:3, s. 605-613q 7:3<605-613x 2588-9311
8564 u https://doi.org/10.1016/j.euo.2023.12.007y Fulltext
8564 u https://umu.diva-portal.org/smash/get/diva2:1849699/FULLTEXT02.pdfx primaryx Raw objecty fulltext:print
8564 u http://dx.doi.org/10.1016/j.euo.2023.12.007x freey FULLTEXT
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-533106
8564 8u https://doi.org/10.1016/j.euo.2023.12.007
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-223032
8564 8u https://lup.lub.lu.se/record/ae76ad2e-73c8-401a-adae-ee145996bc66

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